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3-[2-(azepan-1-yl)ethyl]-2-phenyl-1H-indole

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Identification
Molecular formula
C23H26N2
CAS number
104386-41-8
IUPAC name
3-[2-(azepan-1-yl)ethyl]-2-phenyl-1H-indole
State
State

At room temperature, 3-[2-(azepan-1-yl)ethyl]-2-phenyl-1H-indole is typically a solid. It is stable under standard laboratory conditions and should be handled with care to avoid decomposition.

Melting point (Celsius)
110.00
Melting point (Kelvin)
383.15
Boiling point (Celsius)
380.00
Boiling point (Kelvin)
653.15
General information
Molecular weight
308.47g/mol
Molar mass
308.4450g/mol
Density
1.1812g/cm3
Appearence

This compound appears as a crystalline solid. It may vary in color, typically being white to off-white, depending on purity and specific processing techniques employed.

Comment on solubility

Solubility of 3-[2-(azepan-1-yl)ethyl]-2-phenyl-1H-indole

The solubility of 3-[2-(azepan-1-yl)ethyl]-2-phenyl-1H-indole is influenced by several key factors that determine how easily it can dissolve in various solvents. Understanding these factors can provide insights into its potential applications and behaviors in different environments.

Factors Affecting Solubility

  • Polarity: This compound exhibits a degree of non-polar characteristics due to the presence of aromatic rings, influencing its solubility in polar versus non-polar solvents.
  • Hydrogen Bonds: The azepan group may contribute to hydrogen bonding potential, enhancing solubility in polar protic solvents.
  • Molecular Weight: As the molecular weight of the compound increases, solubility can decrease, particularly in solvents that do not match its molecular characteristics.

Typical Solubility Behavior

In practical terms, one might consider the following:

  • This compound may be more soluble in organic solvents such as ethanol or DMSO compared to water.
  • It is advisable to conduct solubility tests in a range of solvents to assess its suitability for specific applications.

The phrase "like dissolves like" can be a guiding principle in predicting the solubility of 3-[2-(azepan-1-yl)ethyl]-2-phenyl-1H-indole. Understanding the interplay of these factors is essential for utilizing this compound effectively in research or industrial settings.

Interesting facts

Interesting Facts about 3-[2-(azepan-1-yl)ethyl]-2-phenyl-1H-indole

3-[2-(azepan-1-yl)ethyl]-2-phenyl-1H-indole is a fascinating compound that has captivated the attention of scientists and researchers alike due to its intriguing structure and potential applications. Here are some noteworthy points:

  • Diverse Pharmacological Activity: This compound falls within the realm of indole derivatives, which are known for their wide range of biological activities, including anti-inflammatory, analgesic, and antidepressant effects. It's interesting to explore how the azepan-1-yl moiety may enhance these activities.
  • Structural Complexity: The presence of an azepane ring in the structure adds significant complexity. This six-membered nitrogen-containing ring may influence the compound's interactions with biological receptors, making it a subject of research in medicinal chemistry.
  • Potential in Drug Development: Compounds like 3-[2-(azepan-1-yl)ethyl]-2-phenyl-1H-indole are often investigated for their potential as pharmaceutical agents. The indole core is a common scaffold for creating new drug candidates, particularly in the treatment of neurological disorders.
  • Research Perspectives: Scientists are continually expanding their understanding of how modifications to the indole structure can lead to greater efficacy or reduced side effects. This compound serves as an exciting model for studying structure-activity relationships in drug design.
  • Applications Beyond Medicine: Besides medicinal applications, compounds resembling 3-[2-(azepan-1-yl)ethyl]-2-phenyl-1H-indole may also find roles in materials science, specifically in the development of organic semiconductors and fluorescent materials.

In conclusion, 3-[2-(azepan-1-yl)ethyl]-2-phenyl-1H-indole poses an intriguing opportunity for exploration in various scientific fields. Its complex structure and potential uses highlight the importance of such compounds in ongoing research and development.

Synonyms
4509-85-7
BRN 0493116
INDOLE, 3-(2-(HEXAHYDRO-1H-AZEPIN-1-YL)ETHYL)-2-PHENYL-
3-(2-(Hexahydro-1H-azepin-1-yl)ethyl)-2-phenylindole
DTXSID80196379
5-22-11-00109 (Beilstein Handbook Reference)
DTXCID40118870
SCHEMBL8524422
L018748
INDOLE,3-(2-(HEXAHYDRO-1H-AZEPIN-1-YL)ETHYL)-2-PHENYL-