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Bromperidol

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Identification
Molecular formula
C21H23BrClNO2
CAS number
10457-90-6
IUPAC name
3-(2-bromo-6,11-dihydrobenzo[c][1]benzothiepin-11-yl)-N,N-dimethyl-propan-1-amine
State
State

At room temperature, Bromperidol is in a solid state.

Melting point (Celsius)
102.00
Melting point (Kelvin)
375.15
Boiling point (Celsius)
430.62
Boiling point (Kelvin)
703.77
General information
Molecular weight
426.42g/mol
Molar mass
426.4150g/mol
Density
1.5500g/cm3
Appearence

Bromperidol appears as a white crystalline powder. It is typically odorless and stable under normal temperatures and pressures.

Comment on solubility

Solubility of 3-(2-bromo-6,11-dihydrobenzo[c][1]benzothiepin-11-yl)-N,N-dimethyl-propan-1-amine

The solubility of 3-(2-bromo-6,11-dihydrobenzo[c][1]benzothiepin-11-yl)-N,N-dimethyl-propan-1-amine can be an intriguing topic given its complex structure. This compound features a unique arrangement of heteroatoms and bulky groups, which can significantly influence its solubility characteristics.

In terms of solubility, here are several important points to consider:

  • Polar vs. Non-Polar: The presence of the amine group generally enhances solubility in polar solvents such as water, whereas the larger aromatic system may favor non-polar solvents.
  • Hydrogen Bonding: The amine moiety can participate in hydrogen bonding, potentially increasing solubility in polar solvents, but steric hindrance from the bulky groups may impede this effect.
  • Solvent Interactions: This compound may show better solubility in dimethyl sulfoxide (DMSO) or ethanol due to favorable interactions between the solvent and the amine group.
  • Effect of Substituents: The bromo substituent can affect the polarity and solubility profile, often resulting in enhanced lipophilicity, complicating solubility in aqueous environments.

In conclusion, the solubility of this compound is likely moderate, with solubility profiles that are highly dependent on the solvent's polarity and the specific conditions of temperature and concentration. Understanding these nuances is crucial for applications in pharmacology and synthesis.

Interesting facts

Interesting Facts about 3-(2-bromo-6,11-dihydrobenzo[c][1]benzothiepin-11-yl)-N,N-dimethyl-propan-1-amine

The compound 3-(2-bromo-6,11-dihydrobenzo[c][1]benzothiepin-11-yl)-N,N-dimethyl-propan-1-amine is a fascinating molecule with several notable attributes:

  • Pharmacological Potential: This compound features a complex structure that may lend itself to a variety of pharmacological applications. Many compounds in the benzothiepin class are considered for their potential therapeutic benefits, ranging from antipsychotic to antidepressant effects.
  • Structural Intricacy: The presence of both thiepin and bromo substituents adds layers of complexity to its molecular geometry, potentially influencing its biological activity and interaction with various enzymes and receptors.
  • Drug Design Insights: The structural attributes of this compound serve as a prime example of how medicinal chemistry leverages specific substitutions to fine-tune biological activity. For instance, introducing a bromine atom can significantly alter the reactivity and binding characteristics of the molecule.
  • Stereochemistry Considerations: The stereochemistry in this molecule could influence how it interacts with biological systems, creating a space for research into its chiral properties and how they affect efficacy.
  • Applications in Research: As a potential lead compound, it may inspire the development of new drugs and experimental therapies, urging researchers to explore its implications in mental health treatment.

In summary, 3-(2-bromo-6,11-dihydrobenzo[c][1]benzothiepin-11-yl)-N,N-dimethyl-propan-1-amine showcases the intersection of organic synthesis and pharmaceutical innovation. Its unique structural elements and potential applications exemplify the richness of contemporary chemical research.