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Chalcone derivative

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Identification
Molecular formula
C15H9ClF2O
CAS number
51414-25-8
IUPAC name
3-(2-chloro-4-fluoro-phenyl)-1-(4-fluorophenyl)prop-2-en-1-one
State
State

At room temperature, this compound is in a solid state, typically existing as a crystalline powder.

Melting point (Celsius)
83.00
Melting point (Kelvin)
356.15
Boiling point (Celsius)
357.00
Boiling point (Kelvin)
630.15
General information
Molecular weight
290.68g/mol
Molar mass
290.6900g/mol
Density
1.2836g/cm3
Appearence

The compound typically appears as a pale yellow crystalline solid. It has a crystalline, powdery texture and may exhibit a slightly shiny surface due to its crystalline nature.

Comment on solubility

Solubility Insights for 3-(2-chloro-4-fluoro-phenyl)-1-(4-fluorophenyl)prop-2-en-1-one

The solubility of 3-(2-chloro-4-fluoro-phenyl)-1-(4-fluorophenyl)prop-2-en-1-one is a multifaceted topic due to its unique molecular structure. Understanding its solubility can be fundamental for various applications in pharmaceuticals and organic chemistry. Here are some key points to consider:

  • Polarity: The presence of several fluorine atoms and a chlorine atom in the structure may significantly influence its polarity, affecting solubility in polar vs. non-polar solvents.
  • Solvent Compatibility: This compound is likely to be more soluble in organic solvents such as ethanol and acetone, rather than in water, due to *expected low polarity* and potential hydrophobic characteristics.
  • Hydrogen Bonding: The ability to form hydrogen bonds plays a crucial role; however, the compound's structure may limit its capacity to engage in extensive hydrogen bonding with water.
  • Concentration and Temperature: Solubility can be influenced by **concentration** and **temperature**, so empirical testing is often necessary for precise solubility measurements.

In conclusion, the solubility of 3-(2-chloro-4-fluoro-phenyl)-1-(4-fluorophenyl)prop-2-en-1-one may be limited in aqueous environments while showing a preference for non-polar or low-polarity organic solvents. Evaluating these characteristics is essential for predicting behavior in various chemical and biological contexts.

Interesting facts

Exploring 3-(2-chloro-4-fluoro-phenyl)-1-(4-fluorophenyl)prop-2-en-1-one

This intriguing compound belongs to the class of chalcones, a group of compounds known for their unique structural properties and applications in various fields, including medicinal chemistry and materials science. Here are some fascinating aspects of this compound:

  • Structural Complexity: The compound showcases a complex arrangement of substituents, featuring both chloro and fluoro groups that significantly influence its chemical behavior.
  • Biological Activity: Chalcones, in general, have been studied for their potential pharmacological benefits. This specific compound may exhibit antioxidant, anti-inflammatory, and anticancer properties, making it a candidate for further research.
  • Versatile Building Blocks: In organic synthesis, chalcones serve as valuable intermediates for producing diverse compounds, including flavonoids and natural products. The unique reactivity of the double bond in its structure allows for a wide range of modifications.
  • Development of Green Chemistry: The synthesis of compounds like this one is often explored in the context of green chemistry to develop sustainable methods that minimize environmental impact.

As a chemistry student or a scientist, understanding the nuances of such compounds is crucial. Their multifaceted roles in both research and practical applications underline the importance of chalcones in modern chemistry. The exploration of compounds like 3-(2-chloro-4-fluoro-phenyl)-1-(4-fluorophenyl)prop-2-en-1-one opens avenues for innovative therapeutic agents and increases our grasp of their role in biological systems. In the words of a prominent chemist, “Every compound tells a story; it's our job to uncover it.”