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Chlorphenamine

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Identification
Molecular formula
C16H19ClN2O
CAS number
113-92-8
IUPAC name
3-[(2-chloro-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yl)oxy]-N,N-dimethyl-propan-1-amine
State
State

At room temperature, Chlorphenamine is a solid compound. It is stable under normal conditions and is usually handled as a solid in its salt form to enhance its pharmaceutical properties.

Melting point (Celsius)
63.00
Melting point (Kelvin)
336.20
Boiling point (Celsius)
324.50
Boiling point (Kelvin)
597.70
General information
Molecular weight
274.80g/mol
Molar mass
274.7980g/mol
Density
1.0970g/cm3
Appearence

Chlorphenamine is typically encountered as a white to off-white crystalline solid. It may have a characteristic odor and is often found in its salt form, such as the maleate, which improves solubility for pharmaceutical applications.

Comment on solubility

Solubility of 3-[(2-chloro-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yl)oxy]-N,N-dimethyl-propan-1-amine

The solubility of 3-[(2-chloro-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yl)oxy]-N,N-dimethyl-propan-1-amine is a complex subject due to the presence of multiple functional groups and structural characteristics. Generally, the solubility of a compound can be influenced by various factors including:

  • Polarity: The interplay between polar and nonpolar regions within the molecule significantly affects how well it dissolves in solvents.
  • Hydrogen Bonding: The ability of the compound to form hydrogen bonds will influence its solubility in polar solvents such as water.
  • Molecular Weight: Higher molecular weight compounds often experience decreased solubility in organic solvents.
  • Functional Groups: The presence of amine groups can enhance solubility in polar solvents, while the hydrophobic regions may deter solubility in such media.

As a rule of thumb, **like dissolves like**, meaning polar substances tend to dissolve well in polar solvents, and nonpolar substances in nonpolar solvents. If 3-[(2-chloro-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yl)oxy]-N,N-dimethyl-propan-1-amine exhibits a balance between these properties, we can expect variable solubility. For accurate solubility data, conducting specific testing under controlled conditions would yield the most reliable results. Ultimately, understanding the solubility characteristics can guide further applications and uses of this intriguing compound.

Interesting facts

Interesting Facts about 3-[(2-chloro-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yl)oxy]-N,N-dimethyl-propan-1-amine

This compound belongs to the class of drugs known as psychotropic agents, making it of particular interest in the fields of medicinal chemistry and pharmacology. Its unique structure, characterized by the presence of a cycloheptaquinoline moiety, offers intriguing possibilities for its interaction with various neurotransmitter systems.

Key Aspects

  • Structure-Activity Relationship (SAR): The compound's distinctive features contribute to its effectiveness and selectivity, showcasing how slight alterations in structure can lead to significant changes in biological activity.
  • Potential Applications: Research indicates that molecules similar to this one may exhibit activity against depression and anxiety disorders, highlighting the importance of developing new therapeutic agents.
  • Synthetic Pathways: The synthesis of this compound involves sophisticated methods that demonstrate the ingenuity of organic synthesis techniques, including cyclization reactions and functional group transformations.
  • Research & Development: Continuous studies are essential as researchers explore its pharmacodynamics and pharmacokinetics, paving the way for innovative drug design.

As a chemistry student, examining this compound not only enhances your grasp of organic synthesis and drug design but also serves as a gateway into the complexities of molecular interactions in biological systems. It underlines the ongoing effort in the scientific community to understand and develop compounds that can effectively target specific pathways in the human body.

In the words of famed chemist Linus Pauling, "Chemistry is the science of substances, their properties, and the changes they undergo." This compound exemplifies that sentiment as it represents a potential substance that could bring about significant changes in therapeutic approaches to mental health.