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2-(2-chlorobenzoyl)benzoxazole

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Identification
Molecular formula
C14H8ClNO2
CAS number
1477-50-5
IUPAC name
3-(2-chlorobenzoyl)-1,3-benzoxazol-2-one
State
State

This compound is a solid at room temperature and typically forms white to off-white crystals.

Melting point (Celsius)
133.00
Melting point (Kelvin)
406.15
Boiling point (Celsius)
421.00
Boiling point (Kelvin)
694.15
General information
Molecular weight
243.67g/mol
Molar mass
243.6600g/mol
Density
1.3959g/cm3
Appearence

2-(2-chlorobenzoyl)benzoxazole appears as a white to off-white crystalline powder. It is typically solid at room temperature.

Comment on solubility

Solubility of 3-(2-chlorobenzoyl)-1,3-benzoxazol-2-one

The solubility of the compound 3-(2-chlorobenzoyl)-1,3-benzoxazol-2-one can be influenced by several factors, primarily its chemical structure and the presence of specific functional groups. Here are some key points to consider:

  • Polarity: The presence of the benzoxazole ring typically indicates moderate polarity, which can lead to variable solubility in different solvents.
  • Solvent Compatibility: This compound is likely soluble in organic solvents such as dimethyl sulfoxide (DMSO) or dimethylformamide (DMF) but may show limited solubility in water due to its hydrophobic character.
  • Functional Group Influence: The chlorobenzoyl moiety may further affect solubility, making the compound more lipophilic. This can enhance solubility in non-polar solvents.

It is important to note that the solubility of such organic compounds can vary significantly based on conditions and the specific solvent used. For scientists studying this compound, performing solubility tests in various solvents is highly suggested to obtain empirical data. As a general rule, like dissolves like—so understanding the nature of the solvent in relation to the compound's structure is key to predicting solubility outcomes.

Interesting facts

Interesting Facts about 3-(2-chlorobenzoyl)-1,3-benzoxazol-2-one

The compound 3-(2-chlorobenzoyl)-1,3-benzoxazol-2-one belongs to a fascinating class of organic compounds known for their unique applications in various fields of science and technology. Here are some intriguing insights:

  • Structural Beauty: This compound showcases an intricate heterocyclic structure that features a benzoxazole ring fused with a chlorobenzoyl moiety, enhancing its chemical complexity and potential reactivity.
  • Role in Drug Development: Compounds of this nature often serve as key intermediates in the synthesis of pharmaceutical agents, particularly in developing anti-cancer and anti-inflammatory drugs. Researchers are particularly interested in their biological properties.
  • Photochemical Properties: This compound exhibits distinct photophysical behavior, making it an attractive candidate for use in optical materials. Scientists are investigating its ability to absorb and emit light, which could lead to applications in sensors and organic light-emitting diodes (OLEDs).
  • Environmental Considerations: Many chlorinated compounds, including this one, are studied for their environmental impact. Investigating their degradation pathways helps in developing greener chemical processes and reducing hazardous waste.
  • Versatility in Synthesis: The synthesis of this compound can involve various methodologies, including palladium-catalyzed coupling reactions and other organic transformations, showcasing the versatility of synthetic organic chemistry.

As we delve deeper into the research surrounding 3-(2-chlorobenzoyl)-1,3-benzoxazol-2-one, it becomes evident that the combination of its chemical properties and potential applications makes it a compound of significant interest in both academic and industrial settings. The exploration of such compounds highlights the way chemistry intersects with technology, health, and environmental science.

Synonyms
2(3H)-BENZOXAZOLONE, 3-(2-CHLOROBENZOYL)-
13787-55-8
3-(2-Chlorobenzoyl)-2(3H)-benzoxazolone
NSC 355369
BRN 0998482
3-(2-Chlorobenzoilo)benzoksazolon-2 [Polish]
3-(2-Chlorobenzoilo)benzoksazolon-2
DTXSID30160348
DTXCID3082839
NSC-355369
3-(2-chlorobenzoyl)-1,3-benzoxazol-2-one
NSC355369
BAS 00394342
2CWZ5B92HH
Oprea1_256604
Oprea1_424500
STK048544
AKOS000511072
CCG-189278
2-Benzoxazolinone, 3-(o-chlorobenzoyl)-
ST51034501
SR-01000316526
SR-01000316526-1
3-[(2-chlorophenyl)carbonyl]-3-hydrobenzoxazol-2-one
3-[(2-chlorophenyl)carbonyl]-1,3-benzoxazol-2(3H)-one