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Trimeprazine iodide

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Identification
Molecular formula
C21H27ClIN2S
CAS number
7493-73-4
IUPAC name
3-(2-chlorophenothiazin-10-yl)propyl-trimethyl-ammonium;iodide
State
State

At room temperature, Trimeprazine iodide is in a solid state. It is typically stable under normal storage conditions and is sensitive to light and moisture, so it should be stored in a tightly closed container in a dry, cool, and well-ventilated place.

Melting point (Celsius)
235.00
Melting point (Kelvin)
508.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
478.84g/mol
Molar mass
478.8410g/mol
Density
1.3400g/cm3
Appearence

Trimeprazine iodide appears as white to slightly yellow crystalline powder. It is generally odorless and has a bitter taste.

Comment on solubility

Solubility of 3-(2-chlorophenothiazin-10-yl)propyl-trimethyl-ammonium;iodide

The compound 3-(2-chlorophenothiazin-10-yl)propyl-trimethyl-ammonium;iodide exhibits interesting solubility characteristics that are important to consider in various applications. Here are some key points regarding its solubility:

  • Solvent Polarity: This compound is likely to be more soluble in polar solvents due to the presence of the quaternary ammonium group, which tends to ionize and interact favorably with polar media.
  • Ionization: As an iodide salt, it is expected to dissolve well in aqueous solutions, breaking apart into its constituent ions: 3-(2-chlorophenothiazin-10-yl)propyl-trimethyl-ammonium cations and iodide anions.
  • Influence of Temperature: Solubility may increase with temperature, a common trend for many salts. This means heating the solution could enhance the dissolution rate.
  • pH Sensitivity: The solubility may also be influenced by the pH of the solution; for example, highly acidic or basic conditions can affect the ionization state of the compound.

Understanding these facets of solubility is crucial for effectively managing the usage of 3-(2-chlorophenothiazin-10-yl)propyl-trimethyl-ammonium;iodide in various chemical processes and formulations.

Interesting facts

Interesting Facts about 3-(2-chlorophenothiazin-10-yl)propyl-trimethyl-ammonium;iodide

The compound 3-(2-chlorophenothiazin-10-yl)propyl-trimethyl-ammonium;iodide is a fascinating chemical with a rich scientific background. It primarily belongs to the class of quaternary ammonium compounds and carries significant implications in various fields, notably in pharmacology.

Key Characteristics

  • Pharmacological Relevance: This compound exhibits properties that make it a subject of interest in pharmaceutical research, especially in the development of antipsychotic medications.
  • Structural Significance: The presence of a chlorinated phenothiazine moiety enhances its effectiveness in biological systems, promoting interactions with neurotransmitter receptors.
  • Ionicity: As a quaternary ammonium salt, it possesses a positive charge, which enhances its solubility in biological environments, facilitating its function inside the human body.

Moreover, the unique structure contributes to its bioactivity, making it a synthetic analog of traditional phenothiazine derivatives, which can affect various neurotransmitter pathways. The compound may also serve as a prototype for further modifications, leading to the discovery of even more potent derivatives.

In terms of applications, this compound can be of utmost importance in:

  1. Design of novel antidepressant and antipsychotic drugs.
  2. Research in neuropharmacology to study drug-receptor interactions.
  3. Development of therapeutic agents targeting specific neural pathways.

As a compound rich in potential, 3-(2-chlorophenothiazin-10-yl)propyl-trimethyl-ammonium;iodide stands at the intersection of chemistry and medicine, making it a captivating subject for further scientific exploration.

Synonyms
Chloropromazine methoiodide
362-02-7
SKF 2680J
M2G9PCA480
NSC-46047
10H-Phenothiazine-10-propanaminium, 2-chloro-N,N,N-trimethyl-, iodide
Chlorpromazine methiodide
AMMONIUM, (3-(2-CHLOROPHENOTHIAZIN-10-YL)PROPYL)TRIMETHYL-, IODIDE
3-(2-chlorophenothiazin-10-yl)propyl-trimethylazanium;iodide
Methochlorpromazine iodide
CHEMBL279905
N-Methylchlorpromazine iodide
NSC 46047
UNII-M2G9PCA480
(3-(2-Chlorophenothiazin-10-yl)propyl)trimethylammonium iodide
SCHEMBL22588152
SKF-2680J
DTXSID60189764
NSC46047
Q27283394