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3-(2-chlorophenyl)isothiourea

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Identification
Molecular formula
C7H7ClN2S
CAS number
1089-71-0
IUPAC name
3-(2-chlorophenyl)isothiourea
State
State

At room temperature, 3-(2-chlorophenyl)isothiourea is typically found in a solid state, reflecting its crystalline structure.

Melting point (Celsius)
155.00
Melting point (Kelvin)
428.15
Boiling point (Celsius)
302.00
Boiling point (Kelvin)
575.15
General information
Molecular weight
188.65g/mol
Molar mass
188.6400g/mol
Density
1.3000g/cm3
Appearence

The compound appears as a crystalline solid, typically white to off-white in color. Its exact appearance can vary slightly based on purity and specific conditions of synthesis.

Comment on solubility

Solubility of 3-(2-chlorophenyl)isothiourea

3-(2-chlorophenyl)isothiourea, bearing the chemical formula C7H7ClN2S, exhibits unique solubility characteristics that are notable in various solvents. Understanding its solubility can aid in applications ranging from chemical synthesis to pharmaceutical formulations. Here are key points regarding its solubility:

  • Polar Solvents: 3-(2-chlorophenyl)isothiourea is generally soluble in polar solvents such as water and alcohols due to its functional groups which engage in hydrogen bonding.
  • Non-Polar Solvents: Conversely, its solubility in non-polar solvents is significantly limited, which is typical for many compounds containing polar functional groups.
  • Temperature Influence: Solubility may increase with temperature, making warm solutions more favorable for dissolving this compound.
  • pH Sensitivity: Changes in pH can affect the ionization of the thiol group, thereby altering solubility patterns; acidic conditions may enhance solubility.

As with many chemical compounds, factors such as molecular structure, presence of electronegative atoms, and intermolecular interactions play a critical role in determining the solubility of 3-(2-chlorophenyl)isothiourea. Exploring these aspects allows chemists to manipulate conditions for optimal use.

Interesting facts

Interesting Facts About 3-(2-chlorophenyl)isothiourea

3-(2-chlorophenyl)isothiourea is a fascinating compound belonging to the class of isothioureas, which are often studied for their diverse biological activities. Here are some noteworthy aspects of this compound:

  • Biological Applications: This compound is known for its potential in medicinal chemistry. Isothiourea derivatives have been researched for their antitumor and antiviral properties, making them intriguing candidates for pharmaceutical development.

  • Mechanistic Studies: The chemical structure of 3-(2-chlorophenyl)isothiourea allows for unique interactions within biological systems. Its 2-chlorophenyl moiety can enhance its reactivity with cellular targets, paving the way for studies on how it can modulate enzyme activity.

  • Environmental Impact: Compounds like this one can be significant in the field of environmental chemistry. Researchers often investigate their stability and degradation pathways in various environments, which is crucial for assessing their ecological safety.

  • Synthesis Challenges: The synthesis of isothioureas can be quite challenging. It typically involves reactions that require careful control of reaction conditions and reagents, making it a delightful topic for chemists interested in synthetic methods.

  • Research Potential: The ongoing investigations into isothioureas like 3-(2-chlorophenyl)isothiourea open up new avenues for understanding the mechanisms of action at the molecular level, which can unveil new therapeutic targets in diseases.

In conclusion, 3-(2-chlorophenyl)isothiourea exemplifies the intersection of chemistry, biology, and environmental science. Its study not only contributes to our understanding of chemical behavior but also holds promise for practical applications that may benefit society.