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Chlorpromazine

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Identification
Molecular formula
C17H19ClN2S
CAS number
50-53-3
IUPAC name
3-(2-chlorothioxanthen-9-ylidene)-N,N-dimethyl-propan-1-amine
State
State

At room temperature, chlorpromazine appears as a solid in its pure form. It is more commonly encountered as a crystalline powder when prepared as a hydrochloride salt.

Melting point (Celsius)
190.00
Melting point (Kelvin)
463.15
Boiling point (Celsius)
240.00
Boiling point (Kelvin)
513.15
General information
Molecular weight
318.87g/mol
Molar mass
318.8650g/mol
Density
1.3200g/cm3
Appearence

Chlorpromazine is a white or off-white crystalline powder. It is often shipped and stored in its hydrochloride salt form due to better stability.

Comment on solubility

Solubility of 3-(2-chlorothioxanthen-9-ylidene)-N,N-dimethyl-propan-1-amine

The solubility of the compound 3-(2-chlorothioxanthen-9-ylidene)-N,N-dimethyl-propan-1-amine (C17H19ClN2S) is influenced by its unique molecular structure. Here are some key points to consider:

  • Polarity: The presence of the chlorine atom and the amine group suggests that the compound has polar characteristics, which may enhance its solubility in polar solvents.
  • Solvent Compatibility: It may exhibit better solubility in common polar solvents such as water and alcohols. However, the overall solubility will also depend on the intermolecular interactions.
  • Hydrophobic Regions: The thioxanthene moiety contributes to a hydrophobic region that could limit solubility in aqueous environments, indicating that it might be less soluble in water.
  • Influence of Temperature: Temperature variations may play a significant role. Generally, an increase in temperature can lead to increased solubility, particularly for solid compounds.

In summary, the solubility of 3-(2-chlorothioxanthen-9-ylidene)-N,N-dimethyl-propan-1-amine is a balance between its polar amine group and non-polar thioxanthene structure. This dual nature suggests the compound can be effectively solubilized in some polar solvents but may face challenges in more hydrophilic environments.

Interesting facts

Explore the Fascinating Compound: 3-(2-Chlorothioxanthen-9-ylidene)-N,N-dimethyl-propan-1-amine

This compound, with its intricate structure, is a member of a class of organic molecules that showcases the versatility of nitrogen-containing compounds in medicinal chemistry. Here are some interesting aspects about it:

  • Dual Functionality: This compound incorporates both a thioxanthene core and an amine functionality, allowing for a wide range of potential applications, particularly in pharmaceuticals.
  • Chlorine's Role: The presence of the chlorine atom in its structure plays a crucial role in enhancing lipophilicity and bioavailability, which can significantly affect its biological activity.
  • Chemical Versatility: The structure allows for various substitutions, making this compound a vital starting point for syntheses in developing new therapeutic agents.
  • Research Potential: Preliminary studies suggest that compounds with similar structures may exhibit anti-cancer or anti-inflammatory properties, highlighting its potential in drug development.
  • Spectroscopic Features: The complex structure allows scientists to utilize sophisticated techniques such as NMR and mass spectrometry to elucidate and confirm the compound's identity.

As a chemist or student delving into organic synthesis, exploring such compounds opens avenues for innovation in medicinal chemistry. Each component of the structure serves its unique purpose, contributing to the compound's overall functionality. The interplay of different atoms and functional groups makes it a captivating subject of study!

In the words of chemist Linus Pauling, “The best way to have a good idea is to have a lot of ideas.” So, let this intricate molecule be the inspiration for your next exploration in chemical research!

Synonyms
4695-61-8
3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-1-propanamine
Spectrum_001436
Chlorprothixene free base
Prestwick0_000348
Prestwick1_000348
Spectrum2_000857
Spectrum3_001564
Spectrum4_000729
NCIStruc1_001079
NCIStruc2_001491
NCIOpen2_008054
NCIOpen2_008709
NCIOpen2_008749
Oprea1_572513
KBioGR_000998
KBioSS_001916
(Z)-3-(2-Chlorothioxanthen-9-ylidene)-NN-dimethylpropylamine
DivK1c_000143
SPBio_000873
SPBio_002336
113-59-7 (free base)
1-Propanamine, 3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-, (Z)-
KBio1_000143
KBio2_001916
KBio2_004484
KBio2_007052
KBio3_002568
DTXSID30859205
NINDS_000143
WSPOMRSOLSGNFJ-UHFFFAOYSA-N
3-(2-chlorothioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine
HMS3651C19
AB07571
s12368
NCI60_004376
SW196895-3
2-chloro-9-(3-dimethylaminopropylidene)-thioxanthene