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Etodolac

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Identification
Molecular formula
C17H21NO3
CAS number
41340-25-4
IUPAC name
3-[2-(diethylamino)ethyl]-1,3-benzoxazine-2,4-dione
State
State

At room temperature, Etodolac is a solid.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.15
Boiling point (Celsius)
524.90
Boiling point (Kelvin)
798.10
General information
Molecular weight
287.36g/mol
Molar mass
287.3580g/mol
Density
1.4134g/cm3
Appearence

Etodolac is typically found as a white or off-white crystalline powder.

Comment on solubility

Solubility of 3-[2-(diethylamino)ethyl]-1,3-benzoxazine-2,4-dione

The solubility of 3-[2-(diethylamino)ethyl]-1,3-benzoxazine-2,4-dione can be explored through several key factors that influence its behavior in various solvents. This compound exhibits some intriguing solubility characteristics that can be summarized as follows:

  • Polar Solvents: The presence of the diethylamino group suggests that the compound may display moderate to good solubility in polar solvents due to its ability to engage in hydrogen bonding.
  • Non-Polar Solvents: It is likely that 3-[2-(diethylamino)ethyl]-1,3-benzoxazine-2,4-dione has limited solubility in non-polar solvents, owing to its structure which contains polar functional groups.
  • pH Dependence: The solubility may also be affected by the pH of the solution, as ionization of the amine group can result in increased solubility in basic conditions.
  • Temperature Influence: As with many organic compounds, increased temperature could lead to better solubility due to enhanced molecular movement.

In summary, the solubility profile of this compound is likely to be characterized by a complex interplay of factors, making it a suitable candidate for experiments that require the manipulation of solubility in varying conditions. Understanding these solubility dynamics can provide insights into its behavioral characteristics in different environments.

Interesting facts

Interesting Facts about 3-[2-(diethylamino)ethyl]-1,3-benzoxazine-2,4-dione

The compound 3-[2-(diethylamino)ethyl]-1,3-benzoxazine-2,4-dione, commonly referred to in chemical literature by its systematic name, is an intriguing member of the benzoxazine family. This class of compounds is notable for its unique structure and versatile properties. Here are some interesting aspects:

  • Structural Diversity: The compound features a benzoxazine ring system, which contributes to its unique chemical reactivity and application potential. The incorporation of a diethylamino group enhances its nitrogen content and can affect its electrophilic behavior.
  • Biological Significance: Compounds like this have been studied for their pharmacological properties. The presence of an amino group often correlates with biological activity, making them targets for drug development.
  • Polymer Potential: Benzoxazines are known for their ability to form thermosetting resins upon polymerization. This feature opens up avenues for their use in advanced materials and coatings, taking advantage of their thermal and chemical stability.
  • Research Interest: Researchers are continually exploring the synthesis of modified benzoxazines to create derivatives with enhanced properties for specific applications in fields like medicine and materials science.

As stated well in literature, “the journey of discovery in organic compounds is a never-ending quest for new applications and innovations.”
This compound exemplifies how structural modifications can lead to novel compounds with significant industrial and therapeutic implications.

In summary, 3-[2-(diethylamino)ethyl]-1,3-benzoxazine-2,4-dione is a fascinating compound that not only serves as a subject for academic research but also shows great promise in real-world applications.

Synonyms
LETIMIDE
Letimida
26513-90-6
S48955N1AL
DTXSID70181097
3-(2-(Diethylamino)ethyl)-2H-1,3-benzoxazine-2,4(3H)-dione
2H-1,3-Benzoxazine-2,4(3H)-dione, 3-(2-(diethylamino)ethyl)-
RefChem:152954
DTXCID80103588
Letimidum
Letimide [INN]
3-[2-(diethylamino)ethyl]-1,3-benzoxazine-2,4-dione
Letimidum [INN-Latin]
Letimida [INN-Spanish]
UNII-S48955N1AL
3-(2-diethylaminoethyl)-1,3-benzoxazine-2,4-dione
SCHEMBL489396
orb2815071
CHEMBL2110855
NS00121717
Q27288572
3-(2-DIETHYLAMINOETHYL)-2H-1,3-BENZOXAZINE-2-4(H)-DIONE