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Diltiazem

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Identification
Molecular formula
C22H26ClN2O4
CAS number
42399-41-7
IUPAC name
3-[2-(diethylamino)ethyl]-1,3-benzoxazol-2-one
State
State

At room temperature, Diltiazem is typically in a solid state, specifically as a crystalline powder.

Melting point (Celsius)
208.00
Melting point (Kelvin)
481.15
Boiling point (Celsius)
340.00
Boiling point (Kelvin)
613.15
General information
Molecular weight
442.55g/mol
Molar mass
442.5470g/mol
Density
1.2800g/cm3
Appearence

Diltiazem appears as a white to off-white crystalline powder in its pure form. The powder is odorless and has a bitter taste.

Comment on solubility

Solubility of 3-[2-(diethylamino)ethyl]-1,3-benzoxazol-2-one

The solubility of 3-[2-(diethylamino)ethyl]-1,3-benzoxazol-2-one can be attributed to its unique structural characteristics. This compound contains both polar and nonpolar functional groups, which can affect how it interacts with solvents.

Some key points regarding its solubility include:

  • Polar Solvents: The presence of the benzoxazole ring and the amino group contributes to solubility in polar solvents, such as water and alcohols.
  • Nonpolar Solvents: However, the diethylamino side chain may confer some degree of lipophilicity, allowing it to dissolve in nonpolar organic solvents as well.
  • Temperature Dependency: Solubility may increase with temperature, as is commonly seen with many organic compounds.
  • pH Influence: The solubility can also be affected by the pH of the solution, particularly if the compound can ionize; this is especially relevant for compounds with amino groups.

In summary, the solubility of 3-[2-(diethylamino)ethyl]-1,3-benzoxazol-2-one is enhanced in polar solvents but may also be substantial in nonpolar environments, making it a versatile compound in various applications. Thus, understanding the solubility profile of this compound is crucial for its effective use in chemical formulations.

Interesting facts

Interesting Facts about 3-[2-(Diethylamino)ethyl]-1,3-benzoxazol-2-one

3-[2-(Diethylamino)ethyl]-1,3-benzoxazol-2-one is a fascinating compound that belongs to the class of benzoxazoles, which are known for their diverse biological activities. Here are some key highlights that make this compound noteworthy:

  • Pharmacological Potential: This compound has been observed to exhibit various pharmacological properties, including potential uses in neuropharmacology due to the presence of the diethylamino group, which can influence its interaction with neurotransmitter systems.
  • Fluorescent Properties: Benzoxazole derivatives often possess fluorescent properties, making them valuable as fluorescent probes in biochemical applications. Such characteristics allow scientists to track molecular processes in living cells.
  • Applications in Organic Synthesis: The synthetic versatility of this compound opens doors for its use as a building block in organic synthesis, especially in creating more complex molecules with therapeutic potential.
  • Bioactivity Research: Research studies have pointed towards its possible role in the development of new drugs, especially in tackling neurological disorders, making it a compound of interest in medicinal chemistry.

In summary, the unique structural features and promising biological activities of 3-[2-(Diethylamino)ethyl]-1,3-benzoxazol-2-one underscore its significance in chemical research and its potential contributions to medicinal science. As scientists continue to explore its properties, there may be even more intriguing discoveries in the pipeline!

Synonyms
3-[2-(diethylamino)ethyl]-1,3-benzoxazol-2(3H)-one
CHEMBL3547717
3-[2-(diethylamino)ethyl]-1,3-benzoxazol-2-one
AI-204/33262054