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Tibolone

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Identification
Molecular formula
C21H28O2
CAS number
5630-53-5
IUPAC name
3-[2-(dimethylamino)ethoxy]-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one
State
State

At room temperature, tibolone is a solid.

Melting point (Celsius)
169.00
Melting point (Kelvin)
442.15
Boiling point (Celsius)
267.00
Boiling point (Kelvin)
540.15
General information
Molecular weight
312.45g/mol
Molar mass
312.4480g/mol
Density
1.1000g/cm3
Appearence

Tibolone is a white or almost white crystalline powder. It is generally fine and has a consistent particle size.

Comment on solubility

Solubility of 3-[2-(dimethylamino)ethoxy]-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one

The solubility of 3-[2-(dimethylamino)ethoxy]-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one can be a complex topic due to its unique chemical structure and functional groups.

  • Solvent Compatibility: This compound's solubility is likely to be influenced by its functional groups. The presence of the dimethylamino group suggests that the compound may have solubility in polar organic solvents.
  • Hydrophobic Characteristics: The dodecahydrocyclopenta[a]phenanthrene core contributes significant hydrophobic character, which may decrease solubility in aqueous environments.
  • Possibility of Hydrogen Bonding: The ethoxy group could enable hydrogen bonding with certain solvents, enhancing solubility in specific polar solvents.

As a result, one could expect the solubility of this compound to be:

  1. High in solvents such as ethanol and DMSO.
  2. Moderate in acetone or other polar aprotic solvents.
  3. Poor in water due to the overarching hydrophobic properties.

In summary, the solubility of this compound is greatly influenced by its structural features, which dictate its interaction with various solvents. Exploring these properties can provide invaluable insights into its potential applications and behavior in different environments.

Interesting facts

Interesting Facts about 3-[2-(Dimethylamino)ethoxy]-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one

This fascinating compound blends unique structural characteristics with intriguing biological potential. As a synthetic derivative, it embodies elements often found in natural products and pharmaceutical compounds. Here are some noteworthy aspects:

  • Complex Structure: With its extensive fused ring system, this compound showcases a core structure typical of steroid-like frameworks, allowing for diverse interactions within biological systems.
  • Dimethylamino Functional Group: The presence of a dimethylamino group enhances its lipophilicity, potentially affecting its absorption and activity in biological environments.
  • Pharmacological Potential: Compounds structurally related to this one are often explored for their therapeutic uses, especially in the realms of anti-cancer and neuroprotective agents.
  • Research Applications: The unique properties make this compound an ideal candidate for studies involving receptors, enzyme inhibition, and cellular signaling pathways.

In the words of chemists, "Complexity often breeds activity," and this compound certainly illustrates that principle. Its structural intricacies highlight the important relationship between molecular architecture and biological function.

As you immerse yourself in the study of this compound, consider how its unique aspects may contribute to future advancements in medicinal chemistry and pharmacology. The world of chemistry is full of surprises, and each compound tells its own story!