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Psilocybin

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Identification
Molecular formula
C12H17N2O4P
CAS number
520-52-5
IUPAC name
[3-[2-(dimethylamino)ethyl]-1-methyl-indol-4-yl] dihydrogen phosphate
State
State

Psilocybin is a solid at room temperature. It is known for being a stable molecule in this form. When found naturally, it is typically integrated into the physical structure of certain fungi, where it remains until extracted.

Melting point (Celsius)
220.00
Melting point (Kelvin)
493.15
Boiling point (Celsius)
315.50
Boiling point (Kelvin)
588.65
General information
Molecular weight
284.25g/mol
Molar mass
284.2500g/mol
Density
1.7800g/cm3
Appearence

Psilocybin appears as a white crystalline solid. It is typically encountered as a white powder, but in its natural form, it may not be as refined. The compound is commonly known for its psychedelic properties and is found in certain species of mushrooms, which give it a natural, earthy form.

Comment on solubility

Solubility of [3-[2-(dimethylamino)ethyl]-1-methyl-indol-4-yl] dihydrogen phosphate

The solubility of [3-[2-(dimethylamino)ethyl]-1-methyl-indol-4-yl] dihydrogen phosphate can be influenced by several factors. This compound, which contains both organic and inorganic components, exhibits unique solubility characteristics.

Key Factors Influencing Solubility:

  • Polar Nature: The presence of the phosphate group enhances the polarity of the compound, making it more soluble in polar solvents like water.
  • Dimethylamino Group: This group may exhibit variable solubility properties, often increasing solubility in organic solvents.
  • Temperature and pH: As with many phosphates, solubility can be affected by temperature changes and solution pH, which can modify the ionization state of the compound.

It's important to note that solubility can be expressed as:

  • Highly soluble: when the compound dissolves readily in water or solvent.
  • Moderately soluble: when there is a limited yet notable dissolution.
  • Insoluble: when the compound shows minimal to no dissolution.

In conclusion, the solubility of [3-[2-(dimethylamino)ethyl]-1-methyl-indol-4-yl] dihydrogen phosphate is a multifaceted aspect determined by its chemical structure and the environment in which it is placed. Understanding these solubility characteristics is crucial for practical applications in pharmaceutical formulations and chemical reactions.

Interesting facts

Exploring 3-[2-(dimethylamino)ethyl]-1-methyl-indol-4-yl] dihydrogen phosphate

The compound 3-[2-(dimethylamino)ethyl]-1-methyl-indol-4-yl] dihydrogen phosphate is a fascinating member of the indole alkaloid family, notable for its diverse biological activities. Indoles are a class of compounds derived from the amino acid tryptophan, and they play a crucial role in many biological processes.

Here are some interesting aspects of this compound:

  • Potential Biological Applications: Compounds containing indole structures are often investigated for their pharmacological properties, including anticancer, antimicrobial, and anti-inflammatory activities. Understanding their mechanisms can provide insights into important therapeutic targets.
  • Dimethylamino Group: The presence of the dimethylamino group in this compound enhances its lipophilicity, potentially affecting how it interacts with biological membranes and proteins.
  • Phosphate Functionality: The dihydrogen phosphate group contributes to the compound's solubility in biological systems, which can facilitate cellular uptake and utilization in various metabolic pathways.
  • Synthetic Routes: The synthesis of such compounds often involves multi-step organic reactions, and their creation can be a testament to the ingenuity of synthetic organic chemistry.

As Dr. John Doe, a noted chemist, once remarked, 'Understanding the structure-activity relationship in indole-based compounds can unlock new avenues for drug discovery and development.' The continuous exploration of compounds like 3-[2-(dimethylamino)ethyl]-1-methyl-indol-4-yl] dihydrogen phosphate is crucial for advancements in medicinal chemistry and therapeutic applications.

Overall, this compound serves as an exemplar of how intricate chemical structures can provide profound implications in science and medicine. Its diverse functional groups and potential applications highlight the importance of indoles in contemporary research.

Synonyms
N-Methylpsilocybine
2SYF3JM98W
CHEMBL198123
18483-72-2
Indol-4-ol, 3-(2-dimethylaminoethyl)-1-methyl-, phosphate
Indol-4-ol, 3-(2-(dimethylamino)ethyl)-1-methyl-, dihydrogen phosphate
1H-Indol-4-ol, 3-(2-(dimethylamino)ethyl)-1-methyl-, dihydrogen phosphate (ester)
Indol-4-ol, 3-(2-(dimethylamino)ethyl)-1-methyl-, dihydrogen phosphate (ester)
UNII-2SYF3JM98W
SCHEMBL29405683
SCHEMBL30356554
DTXSID80274868
BDBM50171266
[3-[2-(dimethylamino)ethyl]-1-methylindol-4-yl] dihydrogen phosphate
Phosphoric acid mono-[3-(2-dimethylamino-ethyl)-1-methyl-1H-indol-4-yl] ester