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Psilocybin

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Identification
Molecular formula
C12H17N2O4P
CAS number
520-52-5
IUPAC name
[3-[2-(dimethylamino)ethyl]-1H-indol-4-yl] dihydrogen phosphate
State
State

At room temperature, psilocybin is typically a solid. It is commonly encountered in a powdered form when isolated, but it is more often found naturally within the context of psilocybin mushrooms.

Melting point (Celsius)
220.00
Melting point (Kelvin)
493.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
284.25g/mol
Molar mass
284.2500g/mol
Density
1.7800g/cm3
Appearence

Psilocybin is typically described as a white, crystalline powder. It is often found as the active ingredient in certain mushrooms, giving them a characteristic appearance when dried or processed. The pure compound itself is usually not seen outside of scientific research settings.

Comment on solubility

Solubility of [3-[2-(dimethylamino)ethyl]-1H-indol-4-yl] dihydrogen phosphate

The solubility of [3-[2-(dimethylamino)ethyl]-1H-indol-4-yl] dihydrogen phosphate is an intriguing aspect of its chemical behavior. Understanding this compound's solubility can be crucial for its application in various fields, such as pharmaceuticals and biochemistry. Here are several key points to consider:

  • Polar Nature: Due to the presence of the dihydrogen phosphate group, this compound tends to exhibit high polarity, which can enhance its solubility in polar solvents like water.
  • Amine Contribution: The dimethylamino group can also affect solubility, as it can interact favorably with water, due to both hydrogen bonding and ionic interactions.
  • pH Sensitivity: The solubility may vary significantly with changes in pH, highlighting the importance of environmental factors when studying this compound.
  • Crystal Structure: The compound's crystalline structure could also play a role in solubility; solid forms may have different solubility profiles compared to their amorphous counterparts.

In summary, the solubility of [3-[2-(dimethylamino)ethyl]-1H-indol-4-yl] dihydrogen phosphate can be characterized by its polar nature and the presence of functional groups that influence interaction with solvents. Given its potential utility, exploring its solubility in various solvents and conditions is essential for optimizing its applications.

Interesting facts

Interesting Facts about [3-[2-(dimethylamino)ethyl]-1H-indol-4-yl] dihydrogen phosphate

[3-[2-(dimethylamino)ethyl]-1H-indol-4-yl] dihydrogen phosphate is a fascinating compound that merges the intricacies of organic chemistry with the essential functions carried out by phosphates in biological systems. Here are some key points that illustrate its significance:

  • Structural Complexity: This compound features an indole ring, which is a key structure in many pharmacologically important molecules. Indoles are known for their aromatic characteristics and their prevalence in natural products.
  • Biological Relevance: Compounds containing phosphate groups play crucial roles in cellular functions, particularly in energy transfer and storage, signaling, and as components of nucleotides.
  • Potential Pharmacological Applications: The presence of a dimethylaminoethyl group suggests potential for biological activity, possibly influencing neurotransmitter systems or other pharmacodynamic pathways.
  • Synthesis and Functionalization: The synthetic routes to obtain compounds like this can be a point of study, focusing on functionalization techniques that preserve the integrity of the indole structure while introducing phosphoric functionality.
  • Research Implications: Studies around compounds like this often focus on their effects in medicinal chemistry, contributing to the development of new drugs and therapeutics.
  • Interdisciplinary Interest: This compound is not only of interest to chemists but also engages biochemists and pharmacologists, highlighting the collaborative nature of modern scientific research.

As you venture into the world of organic compounds, understanding molecules like [3-[2-(dimethylamino)ethyl]-1H-indol-4-yl] dihydrogen phosphate can give insights into both chemical properties and potential applications that span various fields in science.

Synonyms
Psilocybine
Psilocybin
Cy 39
CY-39
Psilocybinum [INN-Latin]
Psilocibina [INN-Spanish]
Magic mushrooms
HSDB 7365
EINECS 208-294-4
Psilocybine [INN:BAN:DCF]
UNII-2RV7212BP0
BRN 0273158
DTXSID0048898
PSILOCYBIN [MI]
PSILOCYBINE [INN]
PSILOCYBINE [HSDB]
3-[2-(Dimethylamino)ethyl]-1H-indol-4-yl dihydrogen phosphate
PSILOCYBINE [MART.]
PSILOCYBINE [WHO-DD]
DTXCID0028824
4-22-00-05665 (Beilstein Handbook Reference)
INDOL-4-OL, 3-(2-(DIMETHYLAMINO)ETHYL)-, DIHYDROGEN PHOSPHATE
Psilocybine (INN)
[3-[2-(dimethylamino)ethyl]-1H-indol-4-yl] dihydrogen phosphate
Psilocybinum (INN-Latin)
Psilocibina (INN-Spanish)
PSILOCYBINE (MART.)
({3-[2-(dimethylamino)ethyl]-1H-indol-4-yl}oxy)phosphonic acid
3-[2-(Dimethylamino)ethyl]indol-4-ol dihydrogen phosphate ester
1H-Indol-4-ol, 3-[2-(dimethylamino)ethyl]-, dihydrogen phosphate
Indol-4-ol, 3-[2-(dimethylamino)ethyl]-, dihydrogen phosphate (ester)
3-(2-(dimethylamino)ethyl)-1H-indol-4-yl dihydrogen phosphate
((3-(2-(dimethylamino)ethyl)-1H-indol-4-yl)oxy)phosphonic acid
(3-(2-(dimethylazaniumyl)ethyl)-1H-indol-4-yl) hydrogen phosphate
[3-[2-(dimethylazaniumyl)ethyl]-1H-indol-4-yl] hydrogen phosphate
1H-Indol-4-ol, 3-(2-(dimethylamino)ethyl)-, dihydrogen phosphate
3-(2-(Dimethylamino)ethyl)indol-4-ol dihydrogen phosphate ester
(3-(2-(DIMETHYLAMINO)ETHYL)-1H-INDOL-4-YL) DIHYDROGEN PHOSPHATE
Indol-4-ol, 3-(2-(dimethylamino)ethyl)-, dihydrogen phosphate (ester)
Psilocin phosphoric acid ester
Constituent of "magic mushrooms
32'Dimethylaminoethylindol4phosphate
Magic mushrooms, Mushrooms, Shrooms
4PhosphoryloxyomegaN,Ndimethyltryptamine
OPhosphoryl4hydroxyN,Ndimethyltryptamine
3(2Dimethylaminoethyl)indol4yl dihydrogen phosphate
Indol4ol, 3(2(dimethylamino)ethyl), dihydrogen phosphate
3(2(Dimethylamino)ethyl)1Hindol4ol dihydrogen phosphate ester
3-(2-Dimethylaminoethyl)indol-4-yl dihydrogen phosphoric acid
1HIndol4ol, 3(2(dimethylamino)ethyl), dihydrogen phosphate (ester)
3-(2-(Dimethylamino)ethyl)-1H-indol-4-ol dihydrogen phosphoric acid ester
208-294-4
qvdsejdulklhcg-uhfffaoysa-n
Indocybin
520-52-5
Psilocibin
Teonanacatl
Psilocin phosphate ester
Psilocibina
Psilotsibin
Psilocybinum
O-Phosphoryl-4-hydroxy-N,N-dimethyltryptamine
4-Phosphoryloxy-N,N-dimethyltryptamine
3-2'-Dimethylaminoethylindol-4-phosphate
3-(2-(Dimethylamino)ethyl)-1H-indol-4-ol dihydrogen phosphate ester
3-(2-Dimethylaminoethyl)indol-4-yl dihydrogen phosphate
CHEBI:8614
CHEMBL194378
2RV7212BP0
1H-Indol-4-ol, 3-(2-(dimethylamino)ethyl)-, dihydrogen phosphate (ester)
Psilocybin (USAN)
NCGC00247732-01
PSILOCYBIN [USAN]
Psylocybin
Psilocybin (1.0mg/ml in Methanol)
Psilocybin (1mg/ml in Acetonitrile)
Psilocybin (1mg/ml in 1:1 Acetonitrile:Water)
4-Phosphoryloxy-omega-N,N-dimethyltryptamine
DEA No. 7437
1H-Indol-4-ol, 3-[2-(dimethylamino)ethyl]-, dihydrogen phosphate (ester)
X8Q
COMP360
Constituent of Magic mushrooms
SCHEMBL158945
COMP-360
CY39
WZB81943
Tox21_112898
BDBM50171269
PDSP1_001391
PDSP2_001375
DB11664
SB18760
CAS-520-52-5
NS00008179
C07576
D12881
P-7825
Psilocybin 1000 microg/mL in Acetonitrile:Water
Psilocybin, 1mg/ml in Acetonitrile/Water : 1/1
Q208118
3-[2-(Dimethylamino)ethyl]indol-4-yl dihydrogen phosphate
3-[2-(Dimethylamino)ethyl]-1H-indol-4-yl dihydrogen phosphate #
[3-[2-(dimethylamino)ethyl]-1~{H}-indol-4-yl] dihydrogen phosphate
1H-Indol-4-ol, 3-[2-(dimethylamino)ethyl]-, 4-(dihydrogen phosphate)
3-(2-Dimethylaminoethyl)-4-phosphoric acid; 4-Phosphoryl-N,N-dimethyltryptamine; Psilocine phosphate; Psilocybin