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Psilocin

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Identification
Molecular formula
C12H16N2O
CAS number
520-53-6
IUPAC name
3-[2-(dimethylamino)ethyl]-1H-indol-6-ol
State
State

At room temperature, psilocin typically exists in a crystalline solid form. Because of its instability when exposed to air, it is often handled with care to prevent degradation.

Melting point (Celsius)
173.00
Melting point (Kelvin)
446.15
Boiling point (Celsius)
537.00
Boiling point (Kelvin)
810.15
General information
Molecular weight
204.27g/mol
Molar mass
204.2690g/mol
Density
1.2895g/cm3
Appearence

Psilocin typically appears as a white (sometimes off-white) crystalline powder. However, upon exposure to air and light, it can quickly undergo oxidation, turning bluish-green.

Comment on solubility

Solubility of 3-[2-(dimethylamino)ethyl]-1H-indol-6-ol

The solubility of 3-[2-(dimethylamino)ethyl]-1H-indol-6-ol can be influenced by several factors, including its chemical structure, polarity, and the nature of the solvent. Understanding its solubility behavior is essential for its applications in various fields.

Factors Influencing Solubility:

  • Polarity: Compounds with polar functional groups typically have higher solubility in polar solvents, while nonpolar compounds prefer nonpolar solvents.
  • Hydrogen Bonding: The presence of hydroxyl groups (-OH) in 3-[2-(dimethylamino)ethyl]-1H-indol-6-ol allows for strong intermolecular hydrogen bonding, which can enhance solubility in protic solvents.
  • Temperature: Generally, increasing temperature can enhance the solubility of solids in liquids, but it's essential to assess the specific behavior of the compound under different thermal conditions.

As a result, it can be anticipated that 3-[2-(dimethylamino)ethyl]-1H-indol-6-ol may exhibit good solubility in polar solvents such as water and ethanol due to its functional groups. However, it may have limited solubility in nonpolar solvents.

Ultimately, to understand the solubility profile of this compound, experimental data is necessary to confirm these hypotheses and guide its practical usage effectively.

Interesting facts

Interesting Facts About 3-[2-(dimethylamino)ethyl]-1H-indol-6-ol

3-[2-(dimethylamino)ethyl]-1H-indol-6-ol, often referred to in research contexts for its intriguing chemical structure and properties, is a compound that has garnered attention in various fields of science, particularly in medicinal chemistry and pharmacology.

Key Insights:

  • Structure & Function: The compound belongs to the indole family, characterized by its fused benzene and pyrrole rings. This structural feature is significant as indole derivatives are known for their varied biological activities.
  • Biological Activity: Compounds like this one have been studied for their potential to act as neurotransmitter modulators, which may have implications in treating neurological disorders.
  • Research Applications: The presence of a dimethylamino group enhances the lipophilicity of the compound, making it a subject of interest for many drug design studies.
  • Pharmacological Potential: Due to its structural similarities with other known pharmaceuticals, 3-[2-(dimethylamino)ethyl]-1H-indol-6-ol is being investigated for its therapeutic potential against conditions such as depression and anxiety.

As a chemistry student, one might find it fascinating to explore the synthesis methods of such compounds, often utilizing techniques such as reduction and alkylation. Moreover, understanding the reactivity of indoles allows for a greater appreciation of their importance in organic synthesis.

In the words of a noted chemist, “The beauty of chemistry lies in the intricate dance of atoms and their potential to create compounds with extraordinary capabilities.” It encapsulates the essence of studying compounds like 3-[2-(dimethylamino)ethyl]-1H-indol-6-ol, where the potential for discovery is as vibrant as its chemical structure itself!

Synonyms
1476-33-1
INDOL-6-OL, 3-(2-(DIMETHYLAMINO)ETHYL)-
CHEMBL382750
BRN 0160817
6-Hydroxy-N,N-dimethyltryptamine
3-(2-dimethylaminoethyl)-1H-indol-6-ol
3-(2-Dimethylamino-ethyl)-1H-indol-6-ol
5-22-12-00067 (Beilstein Handbook Reference)
6-hydroxy-N-dimethyltryptamine
DTXSID70163752
BDBM50171259
PD180821