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AGN 2979

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Identification
Molecular formula
C13H15N3
CAS number
106509-28-0
IUPAC name
3-[2-(dimethylamino)ethyl]-1H-indole-5-carbonitrile
State
State

AGN 2979 is usually in a solid state at room temperature.

Melting point (Celsius)
116.40
Melting point (Kelvin)
389.55
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
225.29g/mol
Molar mass
225.2880g/mol
Density
1.1986g/cm3
Appearence

It is generally observed as an off-white to light brown crystalline solid.

Comment on solubility

Solubility of 3-[2-(dimethylamino)ethyl]-1H-indole-5-carbonitrile

The solubility of 3-[2-(dimethylamino)ethyl]-1H-indole-5-carbonitrile is influenced by its molecular structure and functional groups. Understanding its solubility properties is crucial for applications in pharmaceuticals and chemical synthesis. Here are some key points to consider:

  • Polarity: The presence of polar functional groups such as the -CN (cyanide) group and the -NH within the indole structure suggests that the compound may exhibit moderate solubility in polar solvents like water and alcohol.
  • Hydrogen Bonding: The potential for hydrogen bonding due to the amine group can enhance solubility in polar solvents, aiding in its dissolution.
  • Hydrophobic Interactions: Conversely, the hydrophobic indole ring may limit solubility in water but could increase solubility in organic solvents.
  • pH Dependence: Solubility can also vary with pH; in acidic or basic conditions, the protonation or deprotonation of the amine group may significantly alter solubility.

In summary, while 3-[2-(dimethylamino)ethyl]-1H-indole-5-carbonitrile is expected to have some degree of solubility in polar solvents, factors such as temperature, pH, and solvent choice can greatly influence its ultimate solubility behavior. Identifying optimal conditions for dissolution is key in harnessing the compound’s full potential.

Interesting facts

Interesting Facts about 3-[2-(dimethylamino)ethyl]-1H-indole-5-carbonitrile

3-[2-(dimethylamino)ethyl]-1H-indole-5-carbonitrile is a fascinating compound that holds significance in both the fields of medicinal chemistry and pharmacology. Here are some intriguing aspects of this compound:

  • Structure and Function: This compound features an indole nucleus, a prominent structural motif in numerous biologically active molecules. The indole ring system is known for its role in various neurotransmitters and has been linked to a range of physiological functions.
  • Pharmacological Potential: Compounds containing indole and dimethylamino groups can exhibit diverse biological activities, including effects on the central nervous system. Research into compounds like this has paved the way for the development of novel therapeutic agents.
  • Research Applications: The unique structure of 3-[2-(dimethylamino)ethyl]-1H-indole-5-carbonitrile makes it a valuable subject in studies aimed at understanding receptor interactions. Its derivatives often serve as important tools in neuroscience and drug development.
  • Versatility in Synthesis: The synthesis of this compound can be approached through various organic chemistry methods. The ability to modify substituents on the indole structure allows chemists to design molecules with tailored properties for specific applications.
  • Potential in Drug Design: Given its unique structure, this compound may provide a scaffold for designing new drugs, particularly in the context of treating disorders related to neurotransmitter regulation, such as depression or anxiety.

As research continues to unravel the complexities of compounds like 3-[2-(dimethylamino)ethyl]-1H-indole-5-carbonitrile, the potential discoveries could lead to significant advancements in therapeutic approaches.

Synonyms
5-Cyano-N,N-dimethyltryptamine
17380-42-6
INDOLE-5-CARBONITRILE, 3-(2-DIMETHYLAMINOETHYL)-
3-(2-Dimethylamino)ethylindole-5-carbonitrile
DTXSID60169667
DTXCID6092158
3-[2-(dimethylamino)ethyl]-1H-indole-5-carbonitrile
3-(2-(Dimethylamino)ethyl)-1H-indole-5-carbonitrile
SCHEMBL1122134
DSNBRTOYUJFTAH-UHFFFAOYSA-N
DA-09298
3-(2-dimethylamino-ethyl)-1H-indole-5-carbonitrile
N,N-dimethyl 2-(5-cyano-1H-indol-3-yl)ethyl-amine