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3-[2-(dimethylamino)ethyl]benzothiophen-5-ol

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Identification
Molecular formula
C12H15NOS
CAS number
29621-98-9
IUPAC name
3-[2-(dimethylamino)ethyl]benzothiophen-5-ol
State
State

The compound is a solid at room temperature.

Melting point (Celsius)
123.50
Melting point (Kelvin)
396.60
Boiling point (Celsius)
374.70
Boiling point (Kelvin)
647.90
General information
Molecular weight
221.31g/mol
Molar mass
221.3140g/mol
Density
1.2464g/cm3
Appearence

The compound is typically a crystalline solid with a powdery appearance. It may be colorless or have a slight tint depending on its purity and form.

Comment on solubility

Solubility of 3-[2-(dimethylamino)ethyl]benzothiophen-5-ol

The solubility of 3-[2-(dimethylamino)ethyl]benzothiophen-5-ol can be evaluated considering several factors that influence its interaction with solvents. This compound, characterized by its unique structure, typically exhibits solubility in various organic solvents.

  • Polar Solvents: Generally, compounds featuring polar groups may show some degree of solubility in polar solvents like water and ethanol, but specific solubility data for this compound may vary.
  • Nonpolar Solvents: Because of its aromatic structure and alkyl groups, 3-[2-(dimethylamino)ethyl]benzothiophen-5-ol is more likely to be soluble in nonpolar solvents such as hexane or dichloromethane.
  • Hydrogen Bonding: The presence of the hydroxyl group may facilitate hydrogen bonding, enhancing solubility in polar protic solvents.

In summary, while 3-[2-(dimethylamino)ethyl]benzothiophen-5-ol shows promise for solubility in organic solvents, experimental solubility tests are essential to determine its exact behavior in different conditions. It is crucial to perform a thorough solubility analysis under varying pH levels and temperature to get a clearer picture. As solubility is a multifaceted property, understanding these nuances is key to its application in chemical processes.

Interesting facts

Interesting Facts about 3-[2-(dimethylamino)ethyl]benzothiophen-5-ol

3-[2-(dimethylamino)ethyl]benzothiophen-5-ol is a fascinating compound that showcases the intricate interplay between chemistry and biology. Below are some engaging insights into this unique chemical:

  • Structural Complexity: This compound features a benzothiophene core, an aromatic structure that is central to various medicinal compounds. The presence of a dimethylamino group enhances its biological activity, making it a subject of interest in pharmaceutical research.
  • Biological Implications: Compounds like this one are often investigated for their potential pharmacological effects, including antidepressant, analgesic, and antitumor activities.
  • Research Applications: The study of benzothiophenes has led to discoveries in neuropharmacology and cancer therapeutics. Researchers are keen on understanding how the structural modifications of compounds can impact their efficacy and safety.
  • Synthesis and Reactions: The synthetic pathways to obtain this compound can involve various organic reactions, including alkylation and reduction. These reactions highlight the versatility of organic chemistry, allowing for the generation of complex molecules from simpler ones.
  • Potential Drug Development: The exploration of compounds like 3-[2-(dimethylamino)ethyl]benzothiophen-5-ol continues to be relevant in the ongoing search for new therapeutic agents. Its unique structure might inspire novel drug designs targeting specific biological pathways.

In conclusion, 3-[2-(dimethylamino)ethyl]benzothiophen-5-ol is not just an assembly of atoms; it represents a wealth of possibilities for innovation in the fields of chemistry and medicine. The journey of exploring such compounds can pave the way for groundbreaking discoveries that may enhance our understanding of complex biological systems.

Synonyms
41548-52-1
BENZO(b)THIOPHEN-5-OL, 3-(2-(DIMETHYLAMINO)ETHYL)-
DTXSID50194408
RefChem:1066474
DTXCID20116899
3-(2-(Dimethylamino)ethyl)benzo(b)thiophene-5-ol
3-(2-(Dimethylamino)ethyl)benzothiophen-5-ol
SCHEMBL25987520