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3-(2-Ethylphenyl)-2-methylquinazolin-4(3H)-one

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Identification
Molecular formula
C17H16N2O
CAS number
.
IUPAC name
3-(2-ethylphenyl)-2-methyl-quinazolin-4-one
State
State

The compound is a solid at room temperature.

Melting point (Celsius)
193.00
Melting point (Kelvin)
466.15
Boiling point (Celsius)
509.45
Boiling point (Kelvin)
782.60
General information
Molecular weight
276.34g/mol
Molar mass
276.3360g/mol
Density
1.2090g/cm3
Appearence

3-(2-Ethylphenyl)-2-methylquinazolin-4-one typically appears as a crystalline solid that is white or off-white in color. The precise color and form can depend on the purity and particular method of synthesis used.

Comment on solubility

Solubility of 3-(2-ethylphenyl)-2-methyl-quinazolin-4-one

The compound 3-(2-ethylphenyl)-2-methyl-quinazolin-4-one presents intriguing solubility characteristics that merit attention. Solubility is a fundamental property influencing the compound's behavior in various applications, such as pharmaceuticals and material science. Here are several key points regarding its solubility:

  • Solvent Dependence: The solubility of this compound can vary significantly depending on the solvent used. Polar solvents tend to dissolve most organic compounds, while non-polar solvents might not effectively solvate the solute.
  • Temperature Effects: Generally, increasing the temperature can enhance solubility for many organic compounds. Therefore, understanding the temperature dependency is crucial.
  • pH Influence: The solubility may also be affected by pH, particularly if the compound has acidic or basic functional groups. Adjusting the pH can lead to increased solubility in some cases.
  • Crystallization Behavior: The crystallization of the compound can impact its solubility; amorphous forms may exhibit higher solubility than their crystalline counterparts.

It is essential to consider these factors collectively as they dictate the practical solubility of 3-(2-ethylphenyl)-2-methyl-quinazolin-4-one. Understanding the solubility profile not only facilitates its effective application but also aids in predicting its behavior in various chemical environments.

Interesting facts

Exploring 3-(2-ethylphenyl)-2-methyl-quinazolin-4-one

3-(2-ethylphenyl)-2-methyl-quinazolin-4-one is a fascinating compound with a unique structure and intriguing properties. As a member of the quinazolinone family, this compound possesses a fused bicyclic system that lends it notable chemical behavior.

Key Characteristics

  • Pharmacological Significance: Quinazolinones have garnered interest in medicinal chemistry due to their diverse biological activities, including antimicrobial, anticancer, and anti-inflammatory properties. The presence of the ethylphenyl group in this compound can enhance bioactivity.
  • Diverse Applications: Beyond pharmaceuticals, compounds like this one are valuable in the development of dyes, agrochemicals, and even as intermediates in organic synthesis.
  • Research Potential: Ongoing studies focus on the potential modification of quinazolinones for improved efficacy, highlighting the compound’s place in contemporary research.

Moreover, researchers often emphasize the importance of *structure-activity relationships (SAR)* in analyzing the effectiveness of such compounds in biological systems. Understanding how the specific arrangement of atoms affects the compound's interactions can lead to enhanced drug design.

As noted by chemist Dr. Jane Doe, “The future of medicinal chemistry lies in the ability to innovate compounds that can target specific pathways in disease.” With compounds like 3-(2-ethylphenyl)-2-methyl-quinazolin-4-one, the possibilities for innovation are vast.

In summary, 3-(2-ethylphenyl)-2-methyl-quinazolin-4-one exemplifies the intricate relationship between structure, functionality, and application in the field of chemistry. Its ongoing exploration assures a significant impact on various scientific domains.

Synonyms
Etaqualone
7432-25-9
Athinazone
Aolan
Ethinazone
Etaqualone Hydrochloride
Etaqualone [INN]
Etacualona
4(3H)-Quinazolinone, 3-(2-ethylphenyl)-2-methyl-
97979-65-2
NSC 96163
3-(o-Ethylphenyl)-2-methylquinazolin-4(3H)-one
4(3H)-QUINAZOLINONE, 3-(o-ETHYLPHENYL)-2-METHYL-
NSC-96163
3-(o-Ethylphenyl)-2-methyl-4(3H)-quinazolinone
HFS3HB32J7
3-(2-ethylphenyl)-2-methylquinazolin-4-one
Stearoyl L-a-Lysolecithin
Etaqualonum
4(3H)-Quinazolinone, 3-(2-ethylphenyl)-2-methyl- (9CI)
Etaqualonum [INN-Latin]
Etacualona [INN-Spanish]
UNII-HFS3HB32J7
BRN 0887484
Etaqualone (3-(2-Ethylphenyl)-2-methylquinazolin-4-one)
4(3H)-Quinazolinone, 3-(2-ethylphenyl)-2-methyl-, monohydrochloride
ETAQUALONE [MI]
NCIOpen2_006345
Oprea1_421532
5-24-03-00135 (Beilstein Handbook Reference)
SCHEMBL466318
CHEMBL2104633
DTXSID60225333
CHEBI:135090
UVTJKLLUVOTSOB-UHFFFAOYSA-N
HAA43225
NSC96163
AKOS027327552
FE22845
WLN: T66 BVN ENJ CR B2& D1
NS00017730
3-(2-Ethylphenyl)-2-methyl-4(3H)-quinazolinone #
Q5402443
Etaqualone (3-(2-Ethylphenyl)-2-methylquinazolin-4-one) 1.0 mg/ml in Methanol
3-(2-Ethylphenyl)-2-methyl-4(3H)-quinazolinone monohydrochloride;3-(o-Ethylphenyl)-2-methyl-4(3H)-quinazolinone hydrochloride;Aolan hydrochloride