Skip to main content

Fluoxetine

ADVERTISEMENT
Identification
Molecular formula
C17H18FNO2
CAS number
54910-89-3
IUPAC name
3-(2-fluoro-6,11-dihydrobenzo[c][1]benzothiepin-11-yl)-N,N-dimethyl-propan-1-amine
State
State

Fluoxetine is in solid form at room temperature.

Melting point (Celsius)
179.00
Melting point (Kelvin)
452.15
Boiling point (Celsius)
371.50
Boiling point (Kelvin)
644.70
General information
Molecular weight
309.42g/mol
Molar mass
309.4200g/mol
Density
1.1200g/cm3
Appearence

Fluoxetine is a white to off-white crystalline solid. It is practically insoluble in water, but it dissolves in organic solvents like alcohol and acetone.

Comment on solubility

Solubility of 3-(2-fluoro-6,11-dihydrobenzo[c][1]benzothiepin-11-yl)-N,N-dimethyl-propan-1-amine

The solubility characteristics of 3-(2-fluoro-6,11-dihydrobenzo[c][1]benzothiepin-11-yl)-N,N-dimethyl-propan-1-amine can be quite complex due to its unique molecular structure. This compound contains various functional groups that can influence its interaction with solvents.

Factors Influencing Solubility:

  • Polarity: The presence of polar functional groups may lead to higher solubility in polar solvents.
  • Molecular size: Larger molecular weights can decrease solubility in certain solvents.
  • Hydrogen bonding: Ability to form hydrogen bonds can significantly enhance solubility in appropriate solvents.

In general, this compound may demonstrate varying degrees of solubility, with expectations for:

  • High solubility in organic solvents such as DMSO or ethanol.
  • Limited solubility in water due to the non-polar portions of the molecule.

It’s important to note that solubility can greatly influence both the bioavailability and pharmacokinetic properties of the compound. As such, conducting experimental solubility tests in different solvents is essential for practical applications. In summary, understanding the solubility of this compound is crucial for its potential utilization in various fields, especially in pharmaceuticals where solubility can dictate drug efficacy.

Interesting facts

3-(2-fluoro-6,11-dihydrobenzo[c][1]benzothiepin-11-yl)-N,N-dimethyl-propan-1-amine

This compound is an intriguing member of the chemical family known as amine derivatives, and it showcases the unique features attributed to its complex structure. Here are some engaging facts about it:

  • Fluorine Influence: The presence of a fluorine atom in the structure enhances the lipophilicity of the compound, which often influences its biological activity and metabolic stability.
  • Thiepin Framework: The benzothiepin component makes it particularly interesting as this framework is known for its diverse pharmacological properties, including potential applications in treating psychiatric disorders.
  • Stereochemistry: The stereochemistry of the side chains in this compound can lead to variances in interaction with biological receptors, making it a great candidate for structure-activity relationship (SAR) studies.
  • Potential Applications: Compounds with similar structures are often explored in medicinal chemistry for their ability to modulate neurotransmitter activities, which can be beneficial in drug design for conditions such as depression or schizophrenia.
  • Current Research: Ongoing research continues to investigate compounds like this one in various assays to determine their efficacy and safety profile, thus paving the way for medical advancements.

As a chemistry student delving into such complex compounds, one must appreciate the intricate balance of synthesis, structure, and function. The study of such compounds can lead to significant breakthroughs in various pharmaceutical applications, demonstrating the importance of chemical diversity in medicinal chemistry.