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Naproxen

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Identification
Molecular formula
C14H14O3
CAS number
22204-53-1
IUPAC name
3-(2-furyl)-2-(1-naphthyl)propanoic acid
State
State

At room temperature, Naproxen is a solid. It appears as crystalline due to its molecular structure.

Melting point (Celsius)
153.00
Melting point (Kelvin)
426.15
Boiling point (Celsius)
372.00
Boiling point (Kelvin)
645.15
General information
Molecular weight
230.26g/mol
Molar mass
230.2590g/mol
Density
1.1490g/cm3
Appearence

Naproxen is typically found as a white to off-white crystalline substance. It is practically insoluble in water at neutral pH but is soluble in alcohol, chloroform, and other organic solvents.

Comment on solubility

Solubility of 3-(2-furyl)-2-(1-naphthyl)propanoic acid

The solubility of 3-(2-furyl)-2-(1-naphthyl)propanoic acid is influenced by both its molecular structure and functional groups. This compound exhibits characteristics that affect its interactions with solvents. Here are some key points to consider:

  • Polarity: The presence of polar functional groups can lead to appreciable solubility in polar solvents, while non-polar regions may encourage solubility in non-polar solvents.
  • Hydrogen bonding: The carboxylic acid group can engage in hydrogen bonding, enhancing its solubility in water.
  • Organic solvents: This compound may demonstrate higher solubility in organic solvents such as ethanol, methanol, or acetone due to its aromatic naphthyl and furyl groups.

In general, the solubility of such compounds is not solely determined by a single factor but rather by a combination of the effects mentioned above. Experimentation is often necessary to determine exact solubility values under various conditions. Therefore, understanding the solubility characteristics can guide researchers in selecting appropriate solvents for applications involving this compound.

Interesting facts

About 3-(2-furyl)-2-(1-naphthyl)propanoic acid

3-(2-furyl)-2-(1-naphthyl)propanoic acid, often referred to in discussions about various pharmacological applications, is a compound that showcases the intersection of organic chemistry and medicinal science. With its unique structural features, this compound has garnered attention for its potential biological activities.

Noteworthy Characteristics:

  • Multi-functional nature: This compound features both a furyl group and naphthyl moiety, providing a rich platform for further derivatization and screening for biological activity.
  • Potential therapeutic applications: Compounds of this type are often investigated for their anti-inflammatory and analgesic properties, making them valuable in the development of new pain relief medications.
  • Research significance: The study of derivatives derived from 3-(2-furyl)-2-(1-naphthyl)propanoic acid could lead to breakthroughs in drug discovery.

Quote from drug designers: "Compounds with complex structures not only challenge our synthetic skills but also inspire innovative solutions in pharmacology!"

This compound illustrates the synergy of traditional organic chemistry and modern medicinal research. By exploring the structural modifications and interactions of 3-(2-furyl)-2-(1-naphthyl)propanoic acid, scientists may unlock new avenues for treating various conditions, enhancing the quality of life for many patients. Its growing importance in research hints at the exciting possibilities it holds for the future of medicinal chemistry.