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Naproxen

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Identification
Molecular formula
C14H14O3
CAS number
22204-53-1
IUPAC name
3-(2-furyl)-2-(2-methyl-1-naphthyl)propanoic acid
State
State

At room temperature, Naproxen is in a solid state. It is generally available in the form of tablets, capsules, or suspensions for ease of consumption. Its crystalline structure ensures stability under typical storage conditions.

Melting point (Celsius)
152.00
Melting point (Kelvin)
425.15
Boiling point (Celsius)
215.50
Boiling point (Kelvin)
488.65
General information
Molecular weight
230.26g/mol
Molar mass
230.2590g/mol
Density
1.1220g/cm3
Appearence

Naproxen appears as a white to off-white crystalline powder. It is practically odorless and has a bitter taste. Although it may exist in various forms, it typically maintains a consistent crystalline structure.

Comment on solubility

Solubility of 3-(2-furyl)-2-(2-methyl-1-naphthyl)propanoic acid

The solubility of 3-(2-furyl)-2-(2-methyl-1-naphthyl)propanoic acid (often referred to as furyl propanoic acid) is influenced by its unique chemical structure, which incorporates both aromatic and aliphatic features. Understanding the solubility characteristics of this compound provides insight into its potential applications and behavior in various environments.

Factors Affecting Solubility

Several key factors affect the solubility of 3-(2-furyl)-2-(2-methyl-1-naphthyl)propanoic acid:

  • Polarity: The presence of carboxylic acid groups contributes to polar characteristics, enhancing solubility in polar solvents.
  • Hydrophobic Character: The naphthalene and furan rings contribute hydrophobic properties, which may limit solubility in water.
  • Temperature: Solubility generally increases with temperature, which can affect interaction dynamics between solute and solvent.

Solubility Insights

While 3-(2-furyl)-2-(2-methyl-1-naphthyl)propanoic acid shows some solubility in organic solvents such as ethanol and acetone, its aqueous solubility is typically low due to:

  • Increased molecular weight from the naphthyl component.
  • Potential for intermolecular interactions such as π-π stacking that restrict solvation.

In summary, the solubility of 3-(2-furyl)-2-(2-methyl-1-naphthyl)propanoic acid is a complex interplay of its molecular structure and the surrounding environment. As noted, its solubility in polar solvents is enhanced, while aqueous solubility remains limited. This unique solubility profile opens the door for various chemical applications and further studies.

Interesting facts

Interesting Facts about 3-(2-furyl)-2-(2-methyl-1-naphthyl)propanoic acid

3-(2-furyl)-2-(2-methyl-1-naphthyl)propanoic acid, commonly referenced in studies involving organic compounds, has garnered interest for its unique chemical structure and potential applications. Here are some noteworthy points regarding this compound:

  • Biosynthetic Pathways: This compound is intriguing due to its relationship with various biosynthetic pathways, often intersecting with natural products derived from plants.
  • Role in Medicine: Derivatives of similar compounds have been explored for their anti-inflammatory and analgesic properties, showcasing the medicinal potential of such structures.
  • Heterocyclic Influence: The presence of the furyl ring introduces heterocyclic characteristics to the compound, which are significant in the field of pharmacology due to their diverse biological activities.
  • Environmental Impact: Studies may also explore the environmental implications of compounds like this one, particularly in relation to their stability and reactivity in ecological systems.

In the words of a renowned chemist, "The beauty of organic chemistry lies in the endless possibilities of molecular transformations." This compound embodies that spirit, with its layered functionality offering a gateway to numerous research avenues.

Ultimately, 3-(2-furyl)-2-(2-methyl-1-naphthyl)propanoic acid serves as a fascinating subject in chemical research, highlighting the intricate connections between organic molecules and their applications in both nature and technology.

Synonyms
3459-58-3
Acetic acid, 2-(2-furylmethyl)-2-(2-methyl-1-naphthyl)-
BRN 1292249
3-(furan-2-yl)-2-(2-methylnaphthalen-1-yl)propanoic acid
alpha-(2'-Furyl)methyl-2-methyl-1-naphthaleneacetic acid
1-NAPHTHALENEACETIC ACID, alpha-(2'-FURYL)METHYL-2-METHYL-
5-18-06-00655 (Beilstein Handbook Reference)
DTXSID40956097