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Furafylline

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Identification
Molecular formula
C12H12N4O3
CAS number
80288-49-9
IUPAC name
3-(2-furylmethyl)-1,8-dimethyl-7H-purine-2,6-dione
State
State

Furafylline is typically in a solid state at room temperature.

Melting point (Celsius)
223.00
Melting point (Kelvin)
496.15
Boiling point (Celsius)
625.80
Boiling point (Kelvin)
898.95
General information
Molecular weight
246.25g/mol
Molar mass
246.2410g/mol
Density
1.4360g/cm3
Appearence

Furafylline is a white to off-white crystalline powder.

Comment on solubility

Solubility of 3-(2-furylmethyl)-1,8-dimethyl-7H-purine-2,6-dione (C12H12N4O3)

The solubility of 3-(2-furylmethyl)-1,8-dimethyl-7H-purine-2,6-dione is an intriguing aspect of this compound due to its unique structure. Consider the following points regarding its solubility:

  • Solvent Compatibility: This compound is likely to show solubility in polar solvents such as water, due in part to its carbonyl and nitrogen functional groups, which can form hydrogen bonds.
  • Nonpolar Solvents: It may have limited solubility in nonpolar solvents, reflecting the influence of its aromatic furan ring and the overall hydrophobic nature of the purine core.
  • Temperature Effects: Like many organic compounds, its solubility may increase with temperature, making it more soluble in hot solvents than in cold ones.
  • pH Influence: The solubility can also be affected by pH, as ionization of nitrogenous groups can increase solubility in basic conditions.

In summary, while exact solubility data may vary, understanding the factors influencing the solubility of 3-(2-furylmethyl)-1,8-dimethyl-7H-purine-2,6-dione is essential for its applications. The interplay between its polar and nonpolar characteristics makes it a compound of interest in the field of medicinal chemistry.

Interesting facts

Interesting Facts about 3-(2-furylmethyl)-1,8-dimethyl-7H-purine-2,6-dione

This compound is a unique member of the purine family, known for its fascinating structure and potential applications in various fields, including medicinal chemistry and biochemistry.

Key Features

  • Structural Diversity: The incorporation of a furan ring into the purine structure introduces unique chemical properties, enhancing the compound's reactivity and interaction with biological systems.
  • Biological Significance: Compounds similar to this one have shown promise in research related to anti-inflammatory, antiviral, and anticancer activities, making them a subject of interest in drug development.
  • Synthetic Routes: The synthesis of this compound involves multiple steps, often utilizing reactions that form carbon-carbon bonds, showcasing the versatility of organic synthesis techniques.
  • Research and Development: Due to its potential biological activity, ongoing research is investigating the mechanisms by which this compound interacts with various biological targets.

Quotes from Researchers

One researcher noted, "The unique combination of the purine backbone and the furan side group opens new avenues for therapeutic interventions."

This compound not only represents a visually appealing structure but also embodies the intricate relationship between chemistry and biology, providing insight into how minor modifications in molecular architecture can lead to significant changes in biological properties.


Synonyms
Furafylline
80288-49-9
Furafilina
Furafylline [INN]
Furafyllinum
Furafilina [Spanish]
Furafyllinum [Latin]
3-(furan-2-ylmethyl)-1,8-dimethyl-1H-purine-2,6(3H,7H)-dione
3-Furfuryl-1,8-dimethylxanthine
3-(furan-2-ylmethyl)-1,8-dimethyl-7H-purine-2,6-dione
3-(2-Furanylmethyl)-3,7-dihydro-1,8-dimethyl-1H-purine-2,6-dione
C12H12N4O3
C2087G0XX3
1H-Purine-2,6-dione,3-(2-furanylmethyl)-3,9-dihydro-1,8-dimethyl-
FURAFYLLINE [WHO-DD]
CHEMBL405845
DTXSID2045153
Furafyllinum (Latin)
NCGC00015426-04
3-(2-furfuryl)-1,8-dimethyl-7H-purine-2,6-quinone
DTXCID0025153
3-(furan-2-ylmethyl)-1,8-dimethyl-3,7-dihydro-1H-purine-2,6-dione
CAS-80288-49-9
UNII-C2087G0XX3
MFCD00153799
1,8-dimethyl-3-(2'-furfuryl)-1H-purine-2,6-dione
Furafilina;Furafyllinum
Lopac-F-124
Lopac0_000538
SCHEMBL191214
Furafylline, >=98% (HPLC)
CHEBI:165840
KGQZGCIVHYLPBH-UHFFFAOYSA-N
HMS2089A08
HMS3261L17
BCP20952
FDA28849
Tox21 110143
Tox21_110143
Tox21_500538
BDBM50236897
AKOS027380039
Tox21_110143_1
CCG-204628
LP00538
SDCCGSBI-0050521.P002
NCGC00015426-01
NCGC00015426-02
NCGC00015426-03
NCGC00015426-05
NCGC00015426-06
NCGC00015426-07
NCGC00015426-08
NCGC00015426-09
NCGC00015426-14
NCGC00093927-01
NCGC00093927-02
NCGC00093927-03
NCGC00093927-04
NCGC00261223-01
AC-32562
BS-17557
DA-53438
HY-107204
CS-0027630
EU-0100538
F-124
NS00096958
BIM-0050521.0001
D84145
AB01275435-01
SR-01000076233
Q5509469
SR-01000076233-1
3-(2-furylmethyl)-1,8-dimethyl-7H-purine-2,6-dione
3-(uran-2-ylmethyl)-1,8-dimethyl-7H-purine-2,6-dione