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Identification
Molecular formula
C10H16N6O3S3
CAS number
.4433-46-7
IUPAC name
3-[(2-guanidinothiazol-4-yl)methylsulfanyl]-N'-sulfamoyl-propanamidine
State
State

The compound is a solid at room temperature. It can be handled as a powder or as crystalline particles, maintaining its solid-state under normal laboratory conditions.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.15
Boiling point (Celsius)
280.00
Boiling point (Kelvin)
553.15
General information
Molecular weight
348.40g/mol
Molar mass
348.4040g/mol
Density
1.4500g/cm3
Appearence

The compound typically appears as a crystalline solid or powder, often in shades of white to off-white. Detailed characterization of its appearance may depend on additional factors like purity and crystallization.

Comment on solubility

Solubility of 3-[(2-guanidinothiazol-4-yl)methylsulfanyl]-N'-sulfamoyl-propanamidine

The solubility of 3-[(2-guanidinothiazol-4-yl)methylsulfanyl]-N'-sulfamoyl-propanamidine (C10H16N6O3S3) exhibits some notable characteristics:

  • Polar nature: The presence of multiple functional groups, such as guanidino and sulfamoyl groups, contributes to its overall polarity. This is likely to enhance solubility in polar solvents.
  • Solvents: It is expected to be soluble in water and other polar solvents due to hydrogen bonding capabilities.
  • Solubility behavior: The solubility can be affected by temperature and pH, as changes in these factors could influence the ionization state of the compound.
  • Practical applications: Understanding its solubility is key for pharmaceutical formulations and biological interactions, as drug solubility can directly impact efficacy.

As a general principle, compounds with higher molecular weights and complex structures may show variable solubility depending on their specific interactions with solvents. This compound's unique structural features warrant further examination to optimize its use in various applications.

Interesting facts

Interesting Facts About 3-[(2-guanidinothiazol-4-yl)methylsulfanyl]-N'-sulfamoyl-propanamidine

This compound, 3-[(2-guanidinothiazol-4-yl)methylsulfanyl]-N'-sulfamoyl-propanamidine, is quite fascinating due to its complex structure and potential applications in medicinal chemistry. Here are some intriguing aspects:

  • Unique Structural Features: The presence of both guanidine and thiazole groups in its structure gives this compound intriguing biochemical properties. These functional groups are known for their roles in biological systems, particularly in enzyme activity.
  • Therapeutic Potential: Compounds containing thiazole and guanidine moieties are often explored for their pharmacological activities. This specific compound is being investigated for its possible applications in targeting various diseases, including cancer and infectious diseases.
  • Mechanistic Insights: The sulfonamide group (sulfamoyl) contributes to the compound’s ability to interact with biological targets. Researchers are particularly interested in how this group can modulate enzyme function, which is critical for drug design.
  • Research Applications: This compound is part of ongoing research for developing new therapeutics. The synthesis and modification of similar compounds have the potential to yield derivatives with enhanced efficacy or reduced side effects.
  • Multi-Functional Role: Beyond its potential medicinal properties, the varying components of the compound suggest capabilities in affecting biological processes, such as protein synthesis and cell signaling pathways.

In summary, 3-[(2-guanidinothiazol-4-yl)methylsulfanyl]-N'-sulfamoyl-propanamidine is not just interesting for its chemical structure but also for its promising implications in health sciences. As the field of drug design advances, compounds like this one could hold the key to breakthroughs in treatment methodologies.

Synonyms
famotidine
76824-35-6
PEPCID
Famotidinum
Famotidina
Gastridin
Brolin
Gastro
Apogastine
Gastrodomina
Gastrosidin
Antodine
Bestidine
Blocacid
Confobos
Cuantin
Famocid
Famodar
Famodin
Famodine
Famogard
Famonit
Famopsin
Famotal
Famotep
Famotin
Famovane
Famowal
Gastridan
Gastrion
Gastrofam
Huberdina
Ingastri
Invigan
Mensoma
Midefam
Neocidine
Nevofam
Notidin
Nulceran
Nulcerin
Panalba
Pepcidin
Pepfamin
Peptidin
Purifam
Quamatel
Quamtel
Renapepsa
Restadin
Rogasti
Rubacina
Tipodex
Ulcatif
Ulceprax
Ulcofam
Ulfagel
Ulfamid
Ulfinol
Ulgarine
Vagostal
Cronol
Peptan
Topcid
Cepal
Famos
Hacip
Logos
Mosul
Tamin
Ulfam
Apo-Famotidine
Novo-Famotidine
3-[[2-(diaminomethylideneamino)-1,3-thiazol-4-yl]methylsulfanyl]-N'-sulfamoylpropanimidamide
Mylanta AR
Famotidine-13C3
3-(((2-((Diaminomethylene)amino)thiazol-4-yl)methyl)thio)-N'-sulfamoylpropanimidamide
N-Sulfamoyl-3-((2-guanidinothiazol-4-yl)methylthio)propionamide
(1-Amino-3-(((2-((diaminomethylene)amino)-4-thiazolyl)methyl)thio)propylidene)sulfamide
3-(((2-((Aminoiminomethyl)amino)-4-thiazolyl)methyl)thio)-N-(aminosulfonyl)propanimidamide
3-(((2-((Diaminomethylene)amino)-4-thiazolyl)methyl)thio)-N(sup 2)-sulfamoylpropionamidine
MFCD00079297
(Z)-3-{[(2-carbamimidamido-1,3-thiazol-4-yl)methyl]sulfanyl}-N'-sulfamoylpropanimidamide
3-((2-(DIAMINOMETHYLENEAMINO)THIAZOL-4-YL)METHYLTHIO)-N-SULFAMOYLPROPANIMIDAMIDE
Famotidine,(S)
Propanimidamide, 3-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)-
Pepcidin Pepcidine
1185241-48-8
Spectrum_001242
Prestwick0_000104
Prestwick1_000104
Spectrum2_001036
Spectrum3_001427
Spectrum4_000408
KBioGR_000676
KBioSS_001722
DivK1c_000545
SPBio_001251
SPBio_002027
GTPL7074
KBio1_000545
KBio2_001722
KBio2_004290
KBio2_006858
KBio3_002354
NINDS_000545
HMS3372J17
HMS3393A07
HMS3604N21
HMS3655J17
BCP22999
KXB24148
N'-(aminosulfonyl)-3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]propanimidamide
AKOS026750161
AB03031
DB00927
FF23221
LP00497
NCGC00018276-03
Famotidine 100 microg/mL in Acetonitrile
SY058013
DB-056142
NS00004752
SW197397-2
D83176
Q411159
N-sulfamoyl-3-[(2-guanidinothiazol-4-yl)methylthio]propionamidine
3-[[[2-[(diaminomethylene) amino]-4-thiazolyl]methyl]thio]-n2-sulfamoyl propionamidine
3-{[(2-carbamimidamido-1,3-thiazol-4-yl)methyl]sulfanyl}-N-sulfamoylpropanimidamide
3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfon yl)propanimidamide;N-(Aminosulfonyl)-3-[[[2-[(diaminomethyle ne)amino]-4-thiazolyl]methyl]thio]propanimidamide