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Methamphetamine

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Identification
Molecular formula
C10H15N
CAS number
537-46-2
IUPAC name
3-[(2-hydroxy-1-methyl-2-phenyl-ethyl)amino]-1-(3-methoxyphenyl)propan-1-one
State
State

At room temperature, methamphetamine is typically found in a solid state, either as a powder or crystalline form.

Melting point (Celsius)
170.00
Melting point (Kelvin)
443.00
Boiling point (Celsius)
215.00
Boiling point (Kelvin)
488.00
General information
Molecular weight
149.23g/mol
Molar mass
149.2330g/mol
Density
1.0490g/cm3
Appearence

Methamphetamine typically appears as a white, odorless, crystalline powder. However, it can also be found in a crystalline form, known colloquially as "crystal meth," which resembles glass fragments or bluish-white rocks.

Comment on solubility

Solubility of 3-[(2-hydroxy-1-methyl-2-phenyl-ethyl)amino]-1-(3-methoxyphenyl)propan-1-one

The solubility of 3-[(2-hydroxy-1-methyl-2-phenyl-ethyl)amino]-1-(3-methoxyphenyl)propan-1-one is influenced by several factors due to its complex chemical structure. Here are some key points regarding its solubility:

  • Polar Characteristics: The presence of the hydroxyl group (-OH) and the amino group (-NH) contributes to polar interactions, potentially enhancing solubility in polar solvents like water.
  • Hydrophobic Components: The phenyl and methoxy groups introduce hydrophobic characteristics which may limit solubility in highly polar solvents.
  • pH Dependency: The solubility may vary with pH levels, as protonation of the amino group can increase solubility in acidic conditions.
  • Solvent Compatibility: It is expected to be more soluble in organic solvents such as ethanol or methanol compared to water due to its overall structure.

In practical applications, understanding the solubility profile is essential for optimizing formulations and predicting behavior in biological systems. As such, it is important to consider both the polar and non-polar nature of the compound for effective utilization.

Interesting facts

Interesting Facts about 3-[(2-hydroxy-1-methyl-2-phenyl-ethyl)amino]-1-(3-methoxyphenyl)propan-1-one

This intriguing compound belongs to the class of ketones and boasts a complex molecular structure that captivates chemists and pharmaceutical researchers alike. Here are some key insights:

  • Potential Pharmacological Applications: The unique arrangement of functional groups in this compound may contribute to its biological activity, making it a subject of interest for drug discovery.
  • Structure-Activity Relationship (SAR): Understanding the interaction of substituents like the hydroxyl and methoxy groups with biological targets can provide insights into how modifications affect the compound's properties and efficacy.
  • Synthetic Challenges: The multi-step synthesis required to create this compound showcases the sophisticated techniques utilized in organic chemistry, involving selective reactions, protecting group strategies, and possibly asymmetric synthesis.
  • Research Potential: Ongoing studies may reveal further insights into its mechanism of action, which is pivotal in medicinal chemistry, especially concerning the treatment of various diseases.
  • Interdisciplinary Relevance: The combination of organic synthesis, pharmacology, and analytical chemistry surrounding this compound demonstrates the interdisciplinary nature of chemical research.

As a chemistry student or scientist, delving into the detailed study of this compound can deepen your understanding of complex molecular interactions and inspire innovative research directions. The intricacies of its design and potential implications in therapeutic domains present a fascinating area for exploration.

Synonyms
Myofedrin
3-[(1-hydroxy-1-phenylpropan-2-yl)amino]-1-(3-methoxyphenyl)propan-1-one
SCHEMBL152554
CHEMBL1094314
DTXSID50860171
GDYUVHBMFVMBAF-UHFFFAOYSA-N
NS00007661
Q7115929