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Methamphetamine Hydrochloride

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Identification
Molecular formula
C10H15ClNO
CAS number
51-57-0
IUPAC name
3-[(2-hydroxy-1-methyl-2-phenyl-ethyl)amino]-1-(3-methoxyphenyl)propan-1-one;hydrochloride
State
State

At room temperature, methamphetamine hydrochloride is in a solid state, commonly found as a crystalline powder or in crystal form.

Melting point (Celsius)
170.00
Melting point (Kelvin)
443.15
Boiling point (Celsius)
5.50
Boiling point (Kelvin)
278.65
General information
Molecular weight
203.68g/mol
Molar mass
203.6780g/mol
Density
1.0966g/cm3
Appearence

Methamphetamine hydrochloride typically appears as a white crystalline powder or as clear crystals. It is known for being odorless and having a bitter taste.

Comment on solubility

Solubility of 3-[(2-hydroxy-1-methyl-2-phenyl-ethyl)amino]-1-(3-methoxyphenyl)propan-1-one;hydrochloride

The solubility of the compound 3-[(2-hydroxy-1-methyl-2-phenyl-ethyl)amino]-1-(3-methoxyphenyl)propan-1-one;hydrochloride can exhibit interesting behavior due to its unique structure, particularly influenced by the presence of the hydrochloride salt form. Generally, compounds that are in their hydrochloride form tend to show improved solubility in polar solvents such as water.

Key Factors Influencing Solubility:

  • Ionic Nature: The presence of the hydrochloride moiety helps increase solubility in aqueous solutions as ionic compounds are typically more soluble due to their ability to interact with water molecules.
  • Hydrogen Bonding: With functional groups such as hydroxyl (-OH) and amine (-NH) present in the structure, the compound can form hydrogen bonds with water, enhancing its solubility.
  • Hydrophobic Interactions: The phenyl groups may introduce hydrophobic characteristics, which can complicate solubility in non-polar solvents, suggesting limited solubility in organic solvents.

Therefore, it is expected that this compound will be significantly more soluble in polar solvents, specifically water, while displaying reduced solubility in non-polar solvents. When assessing solubility, one might consider the following:

  1. Conduct solubility tests across different solvents to determine the optimal environment for dissolution.
  2. Take into account the temperature, as higher temperatures typically increase solubility for many compounds.
  3. Study the pH influence, especially since the compound exists as a hydrochloride, which might affect solubility in various pH conditions.

In conclusion, while a comprehensive solubility profile would require specific experimental data, it is anticipated that the compound will exhibit favorable solubility in aqueous environments owing to its ionic form and potential for hydrogen bonding.

Interesting facts

Exploring 3-[(2-hydroxy-1-methyl-2-phenyl-ethyl)amino]-1-(3-methoxyphenyl)propan-1-one Hydrochloride

3-[(2-hydroxy-1-methyl-2-phenyl-ethyl)amino]-1-(3-methoxyphenyl)propan-1-one hydrochloride is a fascinating compound with several intriguing aspects worth discussing:

Chemical Nature and Versatility

  • This compound belongs to the class of amides, which are known for their application in various organic synthesis processes.
  • It exhibits characteristics of both amines and ketones, allowing for a diverse range of reactivity and potential uses in chemical reactions.

Pharmaceutical Significance

  • Due to its unique structure, this compound may find applications in the pharmaceutical industry, particularly in the development of new medications.
  • Compounds with similar structures have been studied for their potential effects on neurological functions and mood regulation.

Mechanism in Biological Systems

While the detailed biological interactions of this compound are still under investigation, it is important to consider that:

  • Compounds like this often interact with specific receptors in the brain, potentially influencing monoamine levels.
  • Understanding its pharmacodynamics and pharmacokinetics is crucial for evaluating its therapeutic potential.

Research and Development

In the realm of research, this compound opens up possibilities for:

  • Investigating its effects on cellular pathways, especially in studies related to mental health.
  • Exploring its properties further may lead to breakthroughs in finding effective treatments for various conditions.

Overall, the study of 3-[(2-hydroxy-1-methyl-2-phenyl-ethyl)amino]-1-(3-methoxyphenyl)propan-1-one hydrochloride is an exciting field that not only enhances our understanding of complex organic compounds but also bridges the gap between chemistry and biomedical applications. As research continues, this compound has the potential to contribute significantly to scientific advancements in multiple domains.

Synonyms
16648-69-4
3-[(2-Hydroxy-1-methyl-2-phenylethyl)amino]-3'-methoxypropiophenone hydrochloride
DL-Oxyfedrine hydrochloride
Oxyfedrine DL-form hydrochloride
3-[(1-hydroxy-1-phenylpropan-2-yl)amino]-1-(3-methoxyphenyl)propan-1-one;hydrochloride
3-[(2-hydroxy-1-methyl-2-phenylethyl)amino]-3/'-methoxypropiophenone hydrochloride
Oxyfedrine L-form HCl
Oxyfedrine DL-form HCl
FDA 1576; Ildamen; Modacor
3-((2-Hydroxy-1-methyl-2-phenylethyl)amino)-3'-methoxypropiophenone hydrochloride
EINECS 240-696-5
SCHEMBL27491599
DTXSID60937202
JMUPNNYLJGSMPK-UHFFFAOYSA-N
1-Propanone, 3-((2-hydroxy-1-methyl-2-phenylethyl)amino)-1-(3-methoxyphenyl)-, hydrochloride
NS00085632
3-((1-hydroxy-1-phenylpropan-2-yl)amino)-1-(3-methoxyphenyl)propan-1-one hydrochloride
Propiophenone, 3-((beta-hydroxy-alpha-methylphenethyl)amino)-3'-methoxy-, hydrochloride
(3R)-3-(((1S)-1-Hydroxy-1-phenylpropan-2-yl)amino)-3-methoxy-1-phenylpropan-1-one hydrochloride
3-[(1-Hydroxy-1-phenylpropan-2-yl)amino]-1-(3-methoxyphenyl)propan-1-one--hydrogen chloride (1/1)