Skip to main content

Dantrolene

ADVERTISEMENT
Identification
Molecular formula
C14H10N4O5
CAS number
7261-97-4
IUPAC name
3-(2-hydroxyethyl)-1,3-diazaspiro[4.4]nonane-2,4-dione
State
State

At room temperature, Dantrolene is in a solid state, appearing as a yellow crystalline powder.

Melting point (Celsius)
263.00
Melting point (Kelvin)
536.10
Boiling point (Celsius)
317.50
Boiling point (Kelvin)
590.60
General information
Molecular weight
314.26g/mol
Molar mass
314.2260g/mol
Density
1.5000g/cm3
Appearence

Dantrolene is a light yellow, crystalline solid. It is sparingly soluble in water and methanol but is more soluble in organic solvents such as ethanol, dimethyl sulfoxide (DMSO), and chloroform.

Comment on solubility

Solubility of 3-(2-hydroxyethyl)-1,3-diazaspiro[4.4]nonane-2,4-dione

The solubility of 3-(2-hydroxyethyl)-1,3-diazaspiro[4.4]nonane-2,4-dione can be influenced by several factors, primarily due to its unique molecular structure. Here are some key points to consider:

  • Polarity: The presence of a hydroxyl group (-OH) typically enhances solubility in polar solvents like water, suggesting that this compound may be soluble to some extent in such environments.
  • Hydrogen Bonding: Due to the hydroxyl group, the compound is likely capable of forming hydrogen bonds, further facilitating its dissolution in polar solvents.
  • Organic Solvents: Given its spirocyclic structure, solubility in organic solvents such as methanol or ethanol might also be favorable due to similar polar characteristics.
  • pH Sensitivity: The solubility can vary with pH levels, indicating that its ionization could influence its ability to dissolve in various media.

In conclusion, while precise solubility data can vary, it is reasonable to anticipate that 3-(2-hydroxyethyl)-1,3-diazaspiro[4.4]nonane-2,4-dione will exhibit notable solubility in polar solvents, primarily due to its hydroxyl group which allows for better interaction with water molecules. The compound's unique structure may also provide insights into its utility in diverse applications where solubility plays a critical role.

Interesting facts

Interesting Facts about 3-(2-hydroxyethyl)-1,3-diazaspiro[4.4]nonane-2,4-dione

3-(2-hydroxyethyl)-1,3-diazaspiro[4.4]nonane-2,4-dione is a fascinating chemical compound with a variety of applications and characteristics that intrigue both scientists and students alike. Here are some compelling facts to consider:

  • Unique Structure: This compound features a spirocyclic structure, which is notable for its intricacy. The term "spiro" refers to the way atoms are connected in a unique overlapping manner, creating rings that share a single atom.
  • Biological Significance: Compounds with similar structures are often studied for their potential biological activities. Many spiro compounds have been found to exhibit interesting pharmacological properties, making them important in medicinal chemistry.
  • Synthesis Challenges: The synthesis of diazaspiro compounds can be quite complex, requiring precise reaction conditions and catalysts. This complexity is part of what makes them a topic of interest in synthetic organic chemistry.
  • Applications: This compound may find uses in various fields, including:
    • Pharmaceuticals: Their potential as biological activity agents opens doors for new drug development.
    • Material Science: The unique chemical properties may enable novel polymer designs and applications.
  • Research Potential: Ongoing research is likely to unveil more about this compound, particularly in understanding its interactions with biological systems and potential uses in therapeutic contexts.
  • Multifunctionality: The presence of both hydroxyl and carbonyl groups indicates the possibility of engaging in various chemical reactions, enhancing its versatility in organic synthesis.

In summary, the exploration of 3-(2-hydroxyethyl)-1,3-diazaspiro[4.4]nonane-2,4-dione demonstrates the beauty and complexity inherent in chemical research. As one delves into this compound, they not only study a molecule but also engage with a world of possibilities that chemistry has to offer.

Synonyms
BRN 0785946
710-88-3
1,3-DIAZASPIRO(4.4)NONANE-2,4-DIONE, 3-(2-HYDROXYETHYL)-
3'-(2-Hydroxyethyl)cyclopentanespiro-5'-hydantoin
DTXSID50221228
5-24-07-00272 (Beilstein Handbook Reference)
DTXCID50143719