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Methdilazine

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Identification
Molecular formula
C18H22N2OS
CAS number
1982-37-2
IUPAC name
3-(2-methoxyphenothiazin-10-yl)-N,N-dimethyl-propan-1-amine
State
State

At room temperature, methdilazine is typically in a solid state, presenting as a crystalline powder.

Melting point (Celsius)
69.50
Melting point (Kelvin)
342.65
Boiling point (Celsius)
329.30
Boiling point (Kelvin)
602.45
General information
Molecular weight
342.48g/mol
Molar mass
342.4760g/mol
Density
0.9511g/cm3
Appearence

Methdilazine appears as a white to off-white crystalline powder. It may have a slightly bitter taste and is usually odorless.

Comment on solubility

Solubility of 3-(2-methoxyphenothiazin-10-yl)-N,N-dimethyl-propan-1-amine

The solubility of 3-(2-methoxyphenothiazin-10-yl)-N,N-dimethyl-propan-1-amine can be quite intriguing due to its unique structure. Generally, the solubility of organic compounds like this one can be influenced by several factors:

  • Polarity: The presence of polar functional groups can enhance solubility in polar solvents such as water.
  • Hydrophobic Regions: Conversely, large non-polar regions may lead to reduced solubility in polar solvents but increased solubility in non-polar solvents.
  • Hydrogen Bonding: Capable of forming hydrogen bonds can lead to increased solubility in suitable solvents.

In the case of 3-(2-methoxyphenothiazin-10-yl)-N,N-dimethyl-propan-1-amine, its aromatic ring and methoxy substitution suggest that it could potentially achieve moderate solubility in organic solvents. However, precise evaluations reveal that:

  1. The solubility in water will likely be limited due to significant hydrophobic character.
  2. Solvents such as ethanol or dimethyl sulfoxide (DMSO) may be more suitable for dissolving this compound.

In summary, the solubility of this compound is characterized by a balance between its hydrophobic and hydrophilic portions, making it essential to select the right solvent for effective dissolution. As with many compounds, experimental data would provide the most reliable insight into its solubility behavior.

Interesting facts

Interesting Facts about 3-(2-Methoxyphenothiazin-10-yl)-N,N-dimethyl-propan-1-amine

3-(2-Methoxyphenothiazin-10-yl)-N,N-dimethyl-propan-1-amine is a compound that combines elements of both organic chemistry and medicinal applications. Here are some captivating insights about this compound:

  • Pharmaceutical Potential: This compound is part of a category known as phenothiazines, which are crucial in the field of pharmacology. Many phenothiazines have been widely used as antipsychotic medications.
  • Structural Diversity: The unique structure of this compound, featuring a methoxy group, adds to its chemical diversity and potential reactivity. This can lead to interesting interactions within biological systems.
  • Biological Activities: Compounds with similar structures often exhibit varied biological activities, including antihistaminic, antiemetic, and sedative properties. Researchers are keen to explore the specific functions of this compound in biological contexts.
  • Research and Development: The synthesis and modification of phenothiazine derivatives like this compound can lead to the development of new therapeutic agents. This makes it a subject of interest in medicinal chemistry research.
  • Historical Significance: Phenothiazines have a remarkable history in medicine, being among the first drugs used to treat psychiatric disorders. The exploration of derivatives continues to build on this legacy.

As you delve into the intricate world of chemical compounds like 3-(2-Methoxyphenothiazin-10-yl)-N,N-dimethyl-propan-1-amine, remember that every molecule has a story to tell, often intertwined with human health and innovation. Keep exploring, as the realm of medicinal chemistry is ever-evolving!

Synonyms
Methopromazine
Methoxypromazine
61-01-8
2-Methoxy Promazine
Neoproma
Tenton
Tentone
2-Methoxypromazine
Metopromazina
Methopromazine [INN]
RP 4632
3-(2-methoxyphenothiazin-10-yl)-N,N-dimethylpropan-1-amine
2-Methoxy-10-(3'-dimethylaminopropyl)phenothiazine
10-(3-Dimethylaminopropyl)-2-methoxyphenothiazine
A6F645Q9HQ
10H-Phenothiazine-10-propanamine, 2-methoxy-N,N-dimethyl-
Methopromazinum
Methopromazinum [INN-Latin]
Metopromazina [INN-Spanish]
EINECS 200-497-6
UNII-A6F645Q9HQ
2-Methoxy-N,N-dimethyl-10H-phenothiazine-10-propanamine; 10-[3-(Dimethylamino)propyl]-2-methoxyphenothiazine; 2-Methoxy-10-(3'-
Mopazin (Salt/Mix)
Mopazine (Salt/Mix)
2-Methoxy-N,N-dimethyl-10H-phenothiazine-10-propanamine
Oprea1_778116
METHOXYPROMAZINE [MI]
SCHEMBL149884
10-[3-(Dimethylamino)propyl]-2-methoxyphenothiazine
METHOPROMAZINE [WHO-DD]
CHEMBL2110655
Phenothiazine, 10-(3-(dimethylamino)propyl)-2-methoxy
DTXSID90209843
CHEBI:135347
FM34072
4632 R.P
NS00034527
METHOXYPROMAZINE TENTONE,METHOPROMAZINE
2-Methoxy-10-[3'-(dimethylamino)propyl]phenothiazine
Q27273690
Phenothiazine, 10-[3-(dimethylamino)propyl]-2-methoxy-
3-(2-Methoxy-10H-phenothiazin-10-yl)-N,N-dimethyl-1-propanamine #