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Amiben

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Identification
Molecular formula
C9H12N2O1S1
CAS number
33089-29-9
IUPAC name
3-[(2-methoxyphenyl)methyleneamino]isothiourea
State
State

At room temperature, the compound is in a solid state.

Melting point (Celsius)
49.50
Melting point (Kelvin)
322.60
Boiling point (Celsius)
455.60
Boiling point (Kelvin)
728.80
General information
Molecular weight
181.27g/mol
Molar mass
181.2560g/mol
Density
1.3035g/cm3
Appearence

The compound appears as a white crystalline solid.

Comment on solubility

Solubility of 3-[(2-methoxyphenyl)methyleneamino]isothiourea

The solubility of the compound 3-[(2-methoxyphenyl)methyleneamino]isothiourea can be an intriguing subject due to its unique structure. Understanding the solubility characteristics of this compound involves several key points:

  • Polar vs. Non-Polar Solvents: This compound, with its isothiourea functional group, tends to exhibit better solubility in polar solvents such as water and alcohols. The presence of polar groups can enhance interactions with the solvent molecules.
  • Hydrogen Bonding: The potential for hydrogen bonding due to the amine and thiourea functionalities significantly influences solubility. Compounds capable of forming hydrogen bonds generally exhibit higher solubility in polar environments.
  • Hydrophobic Interactions: Conversely, the methoxyphenyl group may introduce some hydrophobic characteristics. Thus, the overall solubility can be nuanced, with solubility possibly decreasing in strictly non-polar solvents.
  • pH Dependence: Additionally, the solubility may also vary with pH due to protonation/deprotonation reactions of the amino and thiourea groups, affecting the compound’s ionization state.

In conclusion, while the detailed solubility profile of 3-[(2-methoxyphenyl)methyleneamino]isothiourea may require empirical determination, its polar functionalities likely recommend it for use in polar solvent systems. This emphasizes the importance of solvent choice in the interaction with chemical compounds.

Interesting facts

Interesting Facts about 3-[(2-methoxyphenyl)methyleneamino]isothiourea

3-[(2-methoxyphenyl)methyleneamino]isothiourea is a fascinating compound that plays a significant role in the realm of medicinal chemistry. Here are some intriguing aspects about this compound:

  • Pharmaceutical Potential: This compound is studied for its potential as a pharmaceutical agent, particularly in anti-cancer drug development. The structural features that it possesses make it a target for further exploration in developing therapeutic agents.
  • Mechanistic Insights: The presence of the isothiourea functional group enhances the compound's reactivity, making it an interesting subject for researchers investigating mechanisms of action in biological systems. This includes its influence on enzymatic processes and potential interactions with cellular targets.
  • Structural Diversity: The incorporation of methoxy and phenyl groups contributes to the compound's structural complexity, offering numerous avenues for modification. Scientists often modify such compounds to improve their efficacy and selectivity toward specific biological targets.
  • Research Interest: According to recent studies, isothiourea compounds, likely including this one, show promise in exhibiting anti-inflammatory and antidiabetic properties, expanding their relevance in therapeutics beyond oncology.
  • Synthetic Pathways: The synthesis of 3-[(2-methoxyphenyl)methyleneamino]isothiourea involves interesting reaction mechanisms. Understanding these pathways can lead to more efficient methods of synthesis and better yields, crucial for industrial applications.

As a highlight from a research paper, it was stated that "The multifaceted applications of isothiourea derivatives in drug discovery promise a bright future for this class of compounds." This encapsulates the ongoing interest in studying and optimizing compounds like 3-[(2-methoxyphenyl)methyleneamino]isothiourea.

In conclusion, the exploration of 3-[(2-methoxyphenyl)methyleneamino]isothiourea not only enhances our understanding of its pharmacological activities but also paves the way for future innovations in medicinal chemistry.