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Benproperine

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Identification
Molecular formula
C17H21Cl2NO2
CAS number
22936-19-8
IUPAC name
3-(2-methyl-1-piperidyl)propyl 3,4-dichlorobenzoate
State
State

At room temperature, Benproperine is in a solid state, usually taking on a crystalline form.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
303.20
Boiling point (Kelvin)
576.35
General information
Molecular weight
354.26g/mol
Molar mass
354.2800g/mol
Density
1.1700g/cm3
Appearence

Benproperine appears as a white or off-white crystalline powder. It is typically supplied as a solid form which is odorless or may have a faint characteristic odor.

Comment on solubility

Solubility of 3-(2-methyl-1-piperidyl)propyl 3,4-dichlorobenzoate

The solubility of 3-(2-methyl-1-piperidyl)propyl 3,4-dichlorobenzoate in various solvents plays a crucial role in its applications and behavior in chemical reactions. Understanding its solubility can help predict how it will interact in different environments. Here are some key points to consider:

  • Polar vs Non-Polar Solvents: The presence of chlorine atoms in the molecular structure may influence the compound's solubility in polar solvents. Typically, compounds with multiple chlorines tend to have increased solubility in polar aprotic solvents like DMSO or DMF.
  • Temperature Dependency: Solubility is often temperature-dependent. As the temperature increases, the kinetic energy of the solvent molecules also increases, which can lead to a rise in solubility for many organic compounds.
  • Hydrogen Bonding: The piperidine ring may introduce polar functionalities, thus enhancing solubility in solvents capable of hydrogen bonding.

In general, compounds like 3-(2-methyl-1-piperidyl)propyl 3,4-dichlorobenzoate are expected to have moderate to high solubility in organic polar solvents, primarily due to the interactions facilitated by the functional groups within the structure. As stated, "The key to solubility is the 'like dissolves like' principle," indicating that understanding the polarity and structure of a compound is critical when predicting its solubility characteristics.

Interesting facts

Interesting Facts about 3-(2-methyl-1-piperidyl)propyl 3,4-dichlorobenzoate

3-(2-methyl-1-piperidyl)propyl 3,4-dichlorobenzoate is a fascinating compound with a variety of applications in the field of medicinal chemistry. Here are some noteworthy points regarding this compound:

  • Structure and Function: The compound features a piperidine derivative, which plays a crucial role in its biological activities. The presence of the 3,4-dichlorobenzoate moiety contributes to its potential as a pharmacological agent.
  • Pharmaceutical Applications: Compounds similar to this one are often explored for their ability to interact with specific biological targets. This structure may be investigated for effects on neurotransmitter systems, possibly influencing mood and cognition.
  • Synthesis: The synthesis of compounds like 3-(2-methyl-1-piperidyl)propyl 3,4-dichlorobenzoate can involve various strategies from organic chemistry, highlighting the importance of reaction conditions, catalysts, and reagents for favorable yields.
  • Research Significance: Scientists are particularly interested in pathways that facilitate the synthesis of such compounds because of the therapeutic significance they hold for various disorders, including anxiety and depression.
  • Potential Side Effects: Although this compound may offer therapeutic benefits, like many pharmacological agents, it is essential to study potential side effects and interactions with other medications to ensure safety and efficacy.

As an advanced compound, the exploration of 3-(2-methyl-1-piperidyl)propyl 3,4-dichlorobenzoate not only furthers our understanding of chemistry but also opens doors to innovative treatments in medicine. This makes it a compelling topic for both chemists and healthcare professionals alike!

Synonyms
Piperalin
Pipron
3478-94-2
Caswell No. 575
EL 211
3-(2-Methylpiperidino)propyl 3,4-dichlorobenzoate
HSDB 7058
EINECS 222-455-6
55ZQC8F9JQ
EPA Pesticide Chemical Code 097003
BRN 1584693
1-Piperidinepropanol, 2-methyl-, 3,4-dichlorobenzoate (ester)
BENZOIC ACID, 3,4-DICHLORO-, 3-(2-METHYLPIPERIDINO)PROPYL ESTER
PIPRON [HSDB]
gamma-(2-Methylpiperidino)propyl 3,4-dichlorobenzoate
DTXSID7032634
Benzoic acid, 3,4-dichloro-, 3-(2-methyl-1-piperidinyl)propyl ester
.gamma.-(2-Methylpiperidino)propyl 3,4-dichlorobenzoate
DTXCID5012634
CHEBI:83283
3(2Methylpiperidino)propyl 3,4dichlorobenzoate
gamma(2Methylpiperidino)propyl 3,4dichlorobenzoate
1Piperidinepropanol, 2methyl, 3,4dichlorobenzoate (ester)
Piperidinepropanol, 2-methyl-,3,4-dichlorobenzoate (ester)
rac-3-(2-methylpiperidin-1-yl)propyl 3,4-dichlorobenzoate
Benzoic acid, 3,4dichloro, 3(2methyl1piperidinyl)propyl ester
Benzoic acid, 3,4dichloro, 3(2methylpiperidino)propyl ester
222-455-6
3-(2-methylpiperidin-1-yl)propyl 3,4-dichlorobenzoate
UNII-55ZQC8F9JQ
SCHEMBL23268
CHEBI:83284
DAA47894
NS00015467
Q19298615
1-Piperidinepropanol, 2-methyl-, 3,4-dichlorobenzoate
3-(2-Methyl-1-piperidinyl)propyl 3,4-dichlorobenzoate #
3,4-Dichlorobenzoic acid, 3-(2-methylpiperidino)propyl ester
BENZOIC ACID, 3,4-DICHLORO-, 3-(2-METHYL-1- PIPERIDINYL)PROPYL ESTER