Skip to main content

Docetaxel

ADVERTISEMENT
Identification
Molecular formula
C43H53NO14
CAS number
114977-28-5
IUPAC name
3-(2-methyl-1-piperidyl)propyl 4-chlorobenzoate
State
State

At room temperature, Docetaxel is a solid. It is typically processed and stored as a solid powder form.

Melting point (Celsius)
232.00
Melting point (Kelvin)
505.15
Boiling point (Celsius)
220.00
Boiling point (Kelvin)
493.15
General information
Molecular weight
807.88g/mol
Molar mass
807.8790g/mol
Density
1.2300g/cm3
Appearence

Docetaxel is a white to almost white crystalline powder. Its appearance is fine and it typically comes in powder form ready for further processing into medicinal forms such as injections.

Comment on solubility

Solubility of 3-(2-methyl-1-piperidyl)propyl 4-chlorobenzoate

The solubility of 3-(2-methyl-1-piperidyl)propyl 4-chlorobenzoate can vary significantly depending on the solvent used and the conditions under which it is measured. This compound exhibits characteristics influenced by both the piperidine ring and the aromatic benzoate moiety.

Key points regarding its solubility include:

  • Polar vs. Non-Polar Solvents: Due to the piperidyl group, which contains a nitrogen atom, the compound may exhibit some solubility in polar solvents such as methanol and ethanol. In contrast, its aromatic structure suggests better solubility in non-polar solvents like toluene or chloroform.
  • Hydrophobic and Hydrophilic Balance: The presence of both hydrophobic (the aromatic ring) and hydrophilic (the piperidyl group) components in the molecule creates a unique balance that can enhance solubility in mixed solvent systems.
  • Temperature Dependency: As with many organic compounds, solubility can be temperature-dependent. Increasing temperature may lead to increased solubility due to greater molecular movement.

In practical applications, it is essential to conduct experimental solubility tests under desired conditions to obtain accurate assessments regarding the solubility of 3-(2-methyl-1-piperidyl)propyl 4-chlorobenzoate in different solvents.

Interesting facts

Interesting Facts About 3-(2-methyl-1-piperidyl)propyl 4-chlorobenzoate

3-(2-methyl-1-piperidyl)propyl 4-chlorobenzoate is a fascinating compound that belongs to the class of benzoates, which are often used in various applications, ranging from pharmaceuticals to fragrances. Here are some engaging insights:

  • Pharmaceutical Potential: This compound has been studied for its potential medicinal properties and is often investigated for its role as a drug intermediate in the synthesis of pharmaceuticals.
  • Structure and Function: The structure of 3-(2-methyl-1-piperidyl)propyl 4-chlorobenzoate incorporates a piperidine ring, which is known for imparting certain biological activities, making it a topic of interest in medicinal chemistry.
  • Chlorine Atom Significance: The presence of the chlorine atom in the 4-position of the benzoate moiety can enhance the compound's lipophilicity, which is a key factor influencing its biological activity and ability to traverse cellular membranes.
  • Diverse Applications: Apart from its potential therapeutic uses, compounds of this nature can also serve as building blocks in materials science, agrochemicals, and even in the synthesis of more complex organic frameworks.
  • Research Importance: The ongoing research around compounds like 3-(2-methyl-1-piperidyl)propyl 4-chlorobenzoate provides valuable insights into drug design and development, illustrating the intricate relationship between molecular structure and biological function.

As a reminder, compounds like this spark curiosity not just in the laboratory but also in the vast field of chemical applications, leading to innovations that could impact various industries.

Synonyms
63916-71-2
3-(2-methylpiperidin-1-yl)propyl 4-chlorobenzoate
3-(2'-Methylpiperidino)propyl p-chlorobenzoate
DTXSID40981021
BENZOIC ACID, p-CHLORO-, 3-(2'-METHYLPIPERIDINO)PROPYL ESTER
RefChem:1066585
DTXCID301408294