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Benzocaine Piperazine Hydrochloride

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Identification
Molecular formula
C15H23ClN2O2
CAS number
125541-22-2
IUPAC name
3-(2-methyl-1-piperidyl)propyl benzoate;hydrochloride
State
State

At room temperature, this compound is a solid. It is typically handled in powder form for laboratory use and may need to be stored in a tightly sealed container to prevent moisture absorption and degradation.

Melting point (Celsius)
156.00
Melting point (Kelvin)
429.15
Boiling point (Celsius)
235.00
Boiling point (Kelvin)
508.15
General information
Molecular weight
272.82g/mol
Molar mass
272.8170g/mol
Density
1.1900g/cm3
Appearence

The compound typically appears as a white to off-white powder. It may have a crystalline form and is generally odorless or may have a slight characteristic odor attributed to piperazine compounds.

Comment on solubility

Solubility of 3-(2-methyl-1-piperidyl)propyl benzoate;hydrochloride

The solubility of 3-(2-methyl-1-piperidyl)propyl benzoate; hydrochloride is influenced by several factors, making it a compound of interest in various applications. Generally, this compound exhibits certain characteristics in different solvents:

  • Water Solubility: Being a hydrochloride salt, it tends to be soluble in water due to the presence of the ionic bond in the chloride part of the compound.
  • Organic Solvents: This compound may also demonstrate solubility in organic solvents such as alcohols and acetone, although the degree of solubility can vary based on the solvent's polarity.
  • Temperature Variation: As with many chemical compounds, solubility may increase with elevated temperatures, which can enhance its dissolution in both water and organic solvents.

It is important to note that the solubility can be affected by:

  • pH of the Medium: Altering the pH can impact ionization, thereby influencing solubility.
  • Presence of Other Compounds: Co-solvents or additives can alter the solubility behavior significantly.

In conclusion, the solubility of 3-(2-methyl-1-piperidyl)propyl benzoate; hydrochloride varies considerably with the nature of the solvent and environmental conditions. As stated in the literature, "Understanding the solubility properties is crucial for both the synthesis and application of this compound." This adaptability in solubility can make it valuable in pharmaceutical formulations and research.

Interesting facts

Interesting Facts about 3-(2-methyl-1-piperidyl)propyl benzoate; hydrochloride

This compound belongs to a class of substances known as benzoates, which are esters derived from benzoic acid. It exhibits intriguing properties and applications, making it a subject of interest in various fields of research.

Key Highlights:

  • Pharmaceutical Relevance: Compounds like this one are often investigated for their potential pharmacological effects. The presence of the piperidine ring can influence biological activity, useful in drug development.
  • Neurotransmitter Interaction: The piperidyl group is known for its role in modulating neurotransmitter systems, potentially leading to exciting therapeutic applications in treating neurological disorders.
  • Versatile Synthesis: This compound can be synthesized through various reaction pathways, showcasing the versatility of organic chemistry. Understanding its synthesis can contribute to advancements in medicinal chemistry.
  • Analytical Studies: Researchers often employ techniques like NMR and mass spectrometry to analyze compounds like this. Such studies can provide insights into the structure-activity relationship critical in drug discovery.
  • Potential Side Effects: As with many pharmacologically active compounds, careful evaluation of side effects is essential. Monitoring adverse reactions helps in understanding the safety profile during clinical applications.

In conclusion, 3-(2-methyl-1-piperidyl)propyl benzoate; hydrochloride stands out not only for its structural components but also for its potential roles in medicinal chemistry and pharmacology.

Synonyms
PIPEROCAINE HYDROCHLORIDE
Piperocainium chloride
533-28-8
UNII-Q2RH0XR1MB
Q2RH0XR1MB
Piperocaine hydrochloride [USP]
DTXSID2046709
EINECS 246-315-9
C 2091
2-Methyl-1-piperidinepropanol benzoate hydrochloride
dl-(2-Methylpiperidino)propyl benzoate hydrochloride
o-Aminobenzoyl di(isopropylamino)ethanol, hydrochloride
Methycaine hydrochloride (TN)
Benzoyl-gamma-(2-methylpiperidino)propanol hydrochloride
(+-)-gamma-(2-Methylpiperidyl)propyl benzoate hydrochloride
24561-10-2
DTXCID0026709
Benzoic acid, 3-(2-methylpiperidino)propyl ester, hydrochloride
PIPEROCAINE HYDROCHLORIDE [MI]
PIPEROCAINE HYDROCHLORIDE [WHO-DD]
PIPEROCAINE HYDROCHLORIDE [GREEN BOOK]
Piperocaine hydrochloride (USP)
1-PIPERIDINEPROPANOL, 2-METHYL-, 1-BENZOATE, HYDROCHLORIDE (1:1)
Methycaine hydrochloride
246-315-9
1-piperidinepropanol, 2-methyl-, benzoate (ester), hydrochloride, (+-)-
Piperocaine HCl
Metycaine hydrochloride
Neothesin hydrochloride
3-(2-Methylpiperidino)propyl benzoate hydrochloride
3-Benzoxy-1-(2-methylpiperidino)propane hydrochloride
3-(2-methylpiperidin-1-yl)propyl benzoate;hydrochloride
1-Piperidinepropanol, 2-methyl-, benzoate (ester), hydrochloride
1-PIPERIDINEPROPANOL, 2-METHYL-, BENZOATE (ESTER), HYDROCHLORIDE, (+/-)-
NCGC00167552-01
SCHEMBL503030
CHEMBL2107171
ZXSGQNYQJIUMQN-UHFFFAOYSA-N
Tox21_112547
AKOS024323241
CAS-533-28-8
NS00083919
D02455
SBI-0654194.0001
Q27286928
3-(2-methylpiperidin-1-ium-1-yl)propyl benzoate;chloride
3-(2-METHYLPIPERIDINO)-PROPYL BENZOATE HYDROCHLORIDE