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Identification
Molecular formula
C14H16N2O2
CAS number
123456-78-9
IUPAC name
[3-(2-methylaziridine-1-carbonyl)phenyl]-(2-methylaziridin-1-yl)methanone
State
State

At room temperature, this compound is in a solid state, appearing as crystalline powder. The solid is stable under standard room conditions but should be handled with care due to its reactive aziridine groups.

Melting point (Celsius)
125.00
Melting point (Kelvin)
398.15
Boiling point (Celsius)
280.00
Boiling point (Kelvin)
553.15
General information
Molecular weight
218.29g/mol
Molar mass
218.2850g/mol
Density
1.2340g/cm3
Appearence

The compound appears as a crystalline solid with a white to off-white coloration. It is typically a powdery substance and may have a slight odor characteristic of organic aziridine compounds.

Comment on solubility

Solubility of [3-(2-methylaziridine-1-carbonyl)phenyl]-(2-methylaziridin-1-yl)methanone

The solubility of the compound [3-(2-methylaziridine-1-carbonyl)phenyl]-(2-methylaziridin-1-yl)methanone can be quite complex due to its intricate molecular structure. When assessing solubility, several factors come into play:

  • Polarity: The presence of both phenyl and aziridine groups impacts the compound's overall polarity. Typically, compounds with higher polarity tend to be more soluble in polar solvents, while nonpolar compounds are more soluble in nonpolar solvents.
  • Hydrogen Bonding: The functional groups present may participate in hydrogen bonding, influencing solubility. Compounds capable of forming hydrogen bonds with solvents, such as water or alcohol, generally exhibit increased solubility.
  • Temperature Influence: Solubility often varies with temperature. Increasing temperature can enhance the solubility of many compounds, but this is not a universal rule.
  • Solvent Compatibility: The choice of solvent is crucial. For instance, organic solvents like dimethyl sulfoxide (DMSO) or ethyl acetate may be more effective in dissolving the compound compared to water.

In conclusion, the solubility of [3-(2-methylaziridine-1-carbonyl)phenyl]-(2-methylaziridin-1-yl)methanone is influenced by its molecular characteristics and the surrounding environmental conditions. Careful evaluation in various solvents will be essential for understanding its solubility behaviors in practical applications.

Interesting facts

Interesting Facts About [3-(2-methylaziridine-1-carbonyl)phenyl]-(2-methylaziridin-1-yl)methanone

This compound, with a rather complex name, represents a fascinating intersection of organic chemistry and medicinal chemistry. It showcases the intriguing properties of aziridine derivatives, which are known for their reactivity and versatility in various applications.

Key Highlights:

  • Aziridine Ring: The aziridine moiety is a three-membered nitrogen-containing ring, which imparts unique chemical properties to the compound. Its strained structure makes it an interesting candidate for further functionalization.
  • Pharmacological Potential: Compounds featuring aziridine units often display biological activity, making them valuable in drug discovery. Researchers are exploring their potential as anticancer agents and in the development of novel antibiotics.
  • Mechanistic Insights: The presence of the carbonyl group enhances the electrophilicity of certain positions in the molecule, prompting various nucleophilic attack mechanisms. This feature is crucial in synthetic pathways used by chemists.
  • Versatile Synthesis: The synthesis of compounds like this one often involves innovative synthetic strategies, enabling chemists to create libraries of related compounds for screening in pharmaceutical applications.

In summary, [3-(2-methylaziridine-1-carbonyl)phenyl]-(2-methylaziridin-1-yl)methanone not only exemplifies the rich chemistry associated with aziridine derivatives but also underscores their importance in the quest for new therapeutic agents. As a scientist, understanding such compounds can lead to the development of innovative solutions to some of today's most pressing health challenges.

Synonyms
1,1'-(1,3-phenylenedicarbonyl)bis[2-methylaziridine]
HX 752
N,N'-Bispropyleneisophthalamide
EINECS 231-617-5
1,1'-(1,3-Phenylenedicarbonyl)bis(2-methylaziridine)
AI3-50530
AZIRIDINE, 1,1'-ISOPHTHALOYLBIS(2-METHYL-
Aziridine, 1,1'-(1,3-phenylenedicarbonyl)bis(2-methyl-
DTXSID4052508
Aziridine, 1,1'-(1,3-phenylenedicarbonyl)bis[2-methyl-
Methanone, 1,1'-(1,3-phenylene)bis(1-(2-methyl-1-aziridinyl)-
Methanone, 1,1'-(1,3-phenylene)bis[1-(2-methyl-1-aziridinyl)-
DTXCID2031081
231-617-5
7652-64-4
[3-(2-methylaziridine-1-carbonyl)phenyl]-(2-methylaziridin-1-yl)methanone
Methanone,1,1'-(1,3-phenylene)bis[1-(2-methyl-1-aziridinyl)-
SCHEMBL133281
PQJYXFVJBSRUPG-UHFFFAOYSA-N
HX752
1,1-Isophthaloyl bis[2-methylaziridine]
1,1-Isophthaloyl-bis(2-methylaziridine)
NS00037805