Skip to main content

Tropisetron Hydrochloride

ADVERTISEMENT
Identification
Molecular formula
C17H21Cl2N2O2
CAS number
105826-92-4
IUPAC name
3-(2-methylpiperidin-1-ium-1-yl)propyl 4-chlorobenzoate;chloride
State
State
Solid at room temperature. Tropisetron Hydrochloride has well-defined crystals under normal atmospheric conditions.
Melting point (Celsius)
231.00
Melting point (Kelvin)
504.15
Boiling point (Celsius)
310.00
Boiling point (Kelvin)
583.15
General information
Molecular weight
398.31g/mol
Molar mass
398.3060g/mol
Density
1.1900g/cm3
Appearence

Tropisetron Hydrochloride typically appears as a white to off-white crystalline powder. It is often odorless and hygroscopic, meaning it can readily absorb moisture from the environment.

Comment on solubility

Solubility Overview

The compound 3-(2-methylpiperidin-1-ium-1-yl)propyl 4-chlorobenzoate;chloride presents interesting solubility characteristics influenced by its molecular structure and the presence of charged species. Understanding its solubility is crucial for applications in various industries, particularly in pharmaceuticals and material sciences.

Key Solubility Features

  • Polarity: The presence of the ionic +NH group contributes to the compound's overall polarity, suggesting a potential for higher solubility in polar solvents.
  • Hydrophobic Interactions: The aromatic 4-chlorobenzoate moiety may induce hydrophobic interactions, possibly decreasing solubility in aqueous environments.
  • Solvent Compatibility: Likely soluble in a range of solvents, particularly those that are polar, such as water and alcohols.

In general, the solubility of this compound can be summarized as follows:

  1. High solubility in polar solvents due to ionization.
  2. Variable solubility in organic solvents, influenced by the presence of the hydrophobic aromatic group.
  3. Potential precipitation in low polarity environments or non-polar solvents.

As with many compounds, the specific conditions such as temperature and pH can significantly affect solubility outcomes. Experimentation is key to fully understanding the solubility profile of 3-(2-methylpiperidin-1-ium-1-yl)propyl 4-chlorobenzoate;chloride.

Interesting facts

Interesting Facts about 3-(2-methylpiperidin-1-ium-1-yl)propyl 4-chlorobenzoate; chloride

This compound is a fascinating example of a quaternary ammonium salt, which plays an essential role in various chemical applications. Here are some interesting aspects worth noting:

  • Biological Relevance: The presence of the piperidine ring in its structure suggests potential biological activity. Compounds containing piperidine are often found in a variety of natural products and pharmaceuticals, indicating that this compound may have applications in medicinal chemistry.
  • Quaternary Ammonium Compounds: As a quaternary ammonium compound, it exhibits cationic properties. This makes it a potential candidate for applications as a surfactant or a phase transfer catalyst due to its solubility in both polar and nonpolar solvents.
  • Structure-Activity Relationship: The alteration of substituents, such as the 4-chlorobenzoate group, can significantly influence the compound's reactivity and biological interactions. Understanding these relationships is critical for drug design and development.
  • Potential Synthesis Pathways: The synthesis of such compounds can involve multiple strategies such as nucleophilic substitution or esterification reactions. Knowledge of these pathways is essential for chemists aiming to create specific derivatives for targeted functions.

As a scientist, it is intriguing to explore how modifications in the molecular structure can impact the functionality of such compounds, opening avenues for innovation in drug discovery and material science. The interplay between geometry and electronic structure within this compound deserves further investigation, highlighting the dynamic and evolving nature of chemistry.

In the words of a well-known chemist, "Chemistry is the art of transformation," and compounds like 3-(2-methylpiperidin-1-ium-1-yl)propyl 4-chlorobenzoate; chloride are perfect exemplars of this transformative art.

Synonyms
p-Chlorobenzoic acid 3-(2-methylpiperidino)propyl ester hydrochloride
BENZOIC ACID, p-CHLORO-, 3-(2-METHYLPIPERIDINO)PROPYL ESTER, HYDROCHLORIDE
21969-62-0
RefChem:1079312