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3-(2-methylpropanoyl)-1H-indole-5-carbonitrile

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Identification
Molecular formula
C14H12N2O
IUPAC name
3-(2-methylpropanoyl)-1H-indole-5-carbonitrile
State
State

At room temperature, 3-(2-methylpropanoyl)-1H-indole-5-carbonitrile exists as a solid.

Melting point (Celsius)
120.00
Melting point (Kelvin)
393.00
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.00
General information
Molecular weight
224.27g/mol
Molar mass
224.2700g/mol
Density
1.2000g/cm3
Appearence

3-(2-methylpropanoyl)-1H-indole-5-carbonitrile is generally a white to off-white solid with a crystalline texture.

Comment on solubility

Solubility of 3-(2-methylpropanoyl)-1H-indole-5-carbonitrile

The solubility profile of 3-(2-methylpropanoyl)-1H-indole-5-carbonitrile is influenced by several factors, particularly its molecular structure and functional groups. While specific solubility data may not always be readily available, we can highlight some general tendencies that govern the solubility of this compound:

  • Polarity: The presence of polar functional groups, such as the carbonitrile group, can enhance solubility in polar solvents like water and ethanol.
  • Hydrophobic Nature: The indole ring and the alkyl substituents contribute to a significant hydrophobic character, making the compound more soluble in organic solvents like chloroform or dichloromethane.
  • Temperature Dependence: Solubility may increase with temperature, which is especially relevant in organic chemistry applications since higher temperatures often promote dissolution.
  • Solvent Interaction: The compatibility of this compound with various solvents will depend on solvent polarity, with potential solubility in both polar and non-polar environments.

In conclusion, while the solubility of 3-(2-methylpropanoyl)-1H-indole-5-carbonitrile may vary depending on specific conditions, understanding these influencing factors can aid in predicting its behavior in different chemical environments. As with many organic compounds, it is important to conduct empirical measurements to confirm solubility in the chosen solvent system.

Interesting facts

Interesting Facts about 3-(2-methylpropanoyl)-1H-indole-5-carbonitrile

3-(2-methylpropanoyl)-1H-indole-5-carbonitrile is a unique compound that belongs to the indole family, which is recognized for its diverse chemical properties and biological activities. Here are some engaging facts about this intriguing compound:

  • Structural Significance: The structure of this compound features an indole core, which is a fused ring system consisting of a six-membered benzene ring and a five-membered nitrogen-containing pyrrole ring. This makes it an essential scaffold in many pharmaceutical compounds.
  • Drug Development: Indoles are known for their potential therapeutic effects. Compounds like 3-(2-methylpropanoyl)-1H-indole-5-carbonitrile are often studied for their role in drug design, particularly in fields related to oncology and neurology.
  • Biological Activity: Some derivatives of indole compounds have shown interesting biological activities, including anti-inflammatory, analgesic, and anticancer properties. This raises questions about the pharmacological potential of 3-(2-methylpropanoyl)-1H-indole-5-carbonitrile and its derivatives.
  • Research Opportunities: The study of this compound and its relatives presents numerous opportunities for research into their mechanisms of action and potential applications in medicine. Understanding how this compound interacts with biological systems could lead to significant advancements in therapeutic strategies.
  • Synthesis Pathways: The synthesis of 3-(2-methylpropanoyl)-1H-indole-5-carbonitrile often involves complex organic reactions, providing ample material for students and chemists to explore organic synthesis techniques and methodologies.

As a chemistry student or a researcher, diving into the world of indole derivatives, including 3-(2-methylpropanoyl)-1H-indole-5-carbonitrile, opens up exciting pathways for both theoretical and practical exploration. The interplay of its unique structure, potential biological effects, and synthesis can make studying this compound an invigorating experience.

Synonyms
BRN 0397205
5-Cyano-3-indolyl isopropyl ketone
INDOLE-5-CARBONITRILE, 3-(2-METHYLPROPIONYL)-
3-(2-Methylpropionyl)-5-indolecarbonitrile
17380-21-1
DTXSID20169663
5-22-06-00348 (Beilstein Handbook Reference)
DTXCID6092154