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Nimorazole

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Identification
Molecular formula
C6H10N4O4
CAS number
6506-37-2
IUPAC name
3-(2-nitroimidazol-1-yl)propane-1,2-diol
State
State

At room temperature, nimorazole is typically a solid. It remains stable under standard laboratory conditions, making it convenient for storage and handling.

Melting point (Celsius)
127.00
Melting point (Kelvin)
400.15
Boiling point (Celsius)
325.00
Boiling point (Kelvin)
598.15
General information
Molecular weight
229.21g/mol
Molar mass
229.2060g/mol
Density
1.5100g/cm3
Appearence

Nimorazole is typically found as a crystalline solid. The compound may present as a colorless to pale yellow powder or crystals, depending on its purity and physical state.

Comment on solubility

Solubility of 3-(2-nitroimidazol-1-yl)propane-1,2-diol

The solubility characteristics of 3-(2-nitroimidazol-1-yl)propane-1,2-diol are particularly interesting due to its unique chemical structure and functional groups. Here are some key points regarding its solubility:

  • Polar Nature: The presence of hydroxyl (-OH) groups in the compound enhances its polarity, which generally increases its solubility in polar solvents such as water.
  • Hydrogen Bonding: The hydroxyl groups can engage in hydrogen bonding, which significantly aids in the interaction with solvents, promoting solubility.
  • Solvent Interactions: While water is likely to be a suitable solvent, other polar solvents such as alcohols or dimethyl sulfoxide (DMSO) may also dissolve this compound effectively.
  • Limited Solubility in Nonpolar Solvents: Due to its polar characteristics, 3-(2-nitroimidazol-1-yl)propane-1,2-diol is expected to have limited solubility in nonpolar solvents like hexane or toluene, which lack the capability to interact effectively with the compound’s structure.

As a result of these factors, one can reasonably expect that 3-(2-nitroimidazol-1-yl)propane-1,2-diol will exhibit high solubility in water and other polar solvents, providing valuable insights for its applications in various chemical processes.

Interesting facts

Interesting Facts about 3-(2-nitroimidazol-1-yl)propane-1,2-diol

This intriguing compound, 3-(2-nitroimidazol-1-yl)propane-1,2-diol, is part of a group that showcases the fascinating intersection of medicinal chemistry and organic compounds, particularly in the realm of pharmaceuticals and therapeutic agents.

Key Highlights:

  • Antimicrobial Properties: Compounds like 3-(2-nitroimidazol-1-yl)propane-1,2-diol are often explored for their potential in combating various microbial infections, especially due to their structural similarity to known antimicrobial agents.
  • Nitroimidazole Derivative: As a derivative of nitroimidazole, it is structurally related to metronidazole, a well-known antibiotic, which enhances its therapeutic profile and makes it worthy of study in medical applications.
  • Potential Anticancer Activity: Research has indicated that nitroimidazole-containing compounds can exhibit effects against tumor cells, adding another layer of interest for oncological studies.
  • Diverse Applications: Beyond just its antibacterial capabilities, this compound may also find utility in the development of new drug formulations, improving the efficacy and delivery of other therapeutic agents.

Overall, the exploration of 3-(2-nitroimidazol-1-yl)propane-1,2-diol represents a small but pivotal piece in the vast puzzle of drug discovery, where understanding the complexities of such compounds can lead to breakthroughs in treatment methodologies.

As scientists continue to probe the multifaceted roles of compounds like this one, they often echo the sentiment: "In the world of chemistry, even the smallest of molecules can create the largest impacts."

Synonyms
13551-92-3
Desmethylmisonidazole
Demethylmisonidazole
Ro 5-9963
1,2-Propanediol, 3-(2-nitro-1H-imidazol-1-yl)-
SR 1530
H3N358OVQW
3-(2-Nitro-I-imidazolyl)-1,2-propanediol
NSC261036
NSC-261036
Ro-5-9963
DTXSID50875669
SR-1530
Ro 05-9963
DTXCID501013790
236-932-1
3-(2-Nitro-1H-imidazol-1-yl)propane-1,2-diol
3-(2-nitroimidazol-1-yl)propane-1,2-diol
1-(2,3-dihydroxypropyl)-2-nitroimidazole
3-(2-Nitro-imidazol-1-yl)-propane-1,2-diol
MFCD00866412
MLS003389316
EINECS 236-932-1
1-(2-Nitro-1-imidazolyl)-3-hydroxy-2-propanol
3-(2-Nitro-1H-imidazol-1-yl)-1,2-propanediol
UNII-H3N358OVQW
NSC 261036
3-(2-NITROIMIDAZOL-1-YL)-1,2-PROPANEDIOL
BRN 0613156
1,2-Propanediol, 3-(2-nitroimidazol-1-yl)-
1,2-Propanediol, 3-(2-nitro-1H-imidazol-1-yl)-,
SCHEMBL16473558
NUGLIYXAARVRPQ-UHFFFAOYSA-N
1, 3-(2-nitroimidazol-1-yl)-
AKOS006274249
AS-6352
1, 3-(2-nitro-1H-imidazol-1-yl)-
Ro-05-9963
SMR002048971
1-(2, 3-dihydroxypropyl)-2-nitroimidazole
NS00053409
1, 2-Propanediol, 3-(2-nitroimidazol-1-yl)-
Q27279600
3-(2-(Hydroxy(oxido)amino)-1H-imidazol-1-yl)-1,2-propanediol