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2-(2-Nitrophenyl)-3-phenylpropenoic acid

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Identification
Molecular formula
C15H11NO4
CAS number
54849-56-2
IUPAC name
3-(2-nitrophenyl)-2-phenyl-prop-2-enoic acid
State
State

At room temperature, 2-(2-nitrophenyl)-3-phenylpropenoic acid is in a solid state, characterized by its crystalline structure and yellow hue.

Melting point (Celsius)
201.00
Melting point (Kelvin)
474.15
Boiling point (Celsius)
410.00
Boiling point (Kelvin)
683.15
General information
Molecular weight
255.25g/mol
Molar mass
255.2300g/mol
Density
1.3880g/cm3
Appearence

2-(2-Nitrophenyl)-3-phenylpropenoic acid typically presents as a yellow crystalline solid. The compound may display some variation in color intensity based on purity and form.

Comment on solubility

Solubility of 3-(2-nitrophenyl)-2-phenyl-prop-2-enoic acid

The solubility of 3-(2-nitrophenyl)-2-phenyl-prop-2-enoic acid presents some intriguing characteristics due to its unique structure. Generally, the solubility of compounds can be influenced by various factors, including:

  • Polarity: The presence of the nitro group (-NO2) increases the polarity of the molecule, potentially enhancing its solubility in polar solvents.
  • Hydrogen Bonding: The carboxylic acid group (-COOH) in the compound can participate in hydrogen bonding, which may facilitate greater solubility in water.
  • Structural Interactions: The bulky phenyl rings could hinder solubility in non-polar solvents, affecting overall solubility characteristics.

In summary, while 3-(2-nitrophenyl)-2-phenyl-prop-2-enoic acid may exhibit some solubility in polar solvents due to its functional groups, it is expected to have limited solubility in non-polar solvents. The compound’s specific solubility profile will depend on various environmental conditions, including temperature and the presence of other solutes.

Interesting facts

Interesting Facts about 3-(2-nitrophenyl)-2-phenyl-prop-2-enoic acid

3-(2-nitrophenyl)-2-phenyl-prop-2-enoic acid, commonly referred to in research contexts as a derivative of cinnamic acid, showcases intriguing properties and applications:

  • Application in Organic Synthesis: This compound acts as a significant intermediate in various chemical syntheses. It can be utilized in the preparation of more complex molecules, particularly in pharmaceuticals.
  • Biological Activity: Some studies suggest potential biological activities, including anti-inflammatory and anti-cancer properties, making it a subject of interest in medicinal chemistry.
  • Electronic Properties: Its structure contains both electron-withdrawing (the nitro group) and electron-donating (the phenyl group) elements, which can influence its reactivity and interaction with different chemical environments.
  • Research Importance: Due to its unique structural features, it serves as a pivotal model in the study of structure-activity relationships (SAR) in various compounds.
  • Synthesis Techniques: The synthesis often involves modern organic synthesis techniques, highlighting the relevance of methodologies like Suzuki coupling and other cross-coupling reactions.

In the words of a researcher, “Understanding this compound not only enhances our grasp of organic chemistry but also opens doors to potential applications in drug development.”
It exemplifies the interconnectedness of organic compounds and their significant roles in advancing scientific knowledge and technological innovations.

Synonyms
3-(o-Nitrophenyl)-2-phenylpropenoic acid
MLS002637665
o-Nitro-alpha-phenylzimtsaure
3-(o-Nitrophenyl)-2-phenylacrylic acid
5345-40-4
NCIOpen2_005506
CHEMBL1872007
HMS3079C09
NCI60_014386
SMR001547190