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3-(2-phenylacetyl)-1H-indole-5-carbonitrile

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Identification
Molecular formula
C18H12N2O
CAS number
132367-76-9
IUPAC name
3-(2-phenylacetyl)-1H-indole-5-carbonitrile
State
State
The compound is primarily found in a solid state at room temperature.
Melting point (Celsius)
178.00
Melting point (Kelvin)
451.15
Boiling point (Celsius)
482.30
Boiling point (Kelvin)
755.45
General information
Molecular weight
285.31g/mol
Molar mass
285.3060g/mol
Density
1.2300g/cm3
Appearence

The compound appears as a crystalline solid with a color ranging from white to off-white.

Comment on solubility

Solubility of 3-(2-phenylacetyl)-1H-indole-5-carbonitrile

The solubility of 3-(2-phenylacetyl)-1H-indole-5-carbonitrile presents interesting characteristics that can influence its usage in various applications. Understanding its solubility can be summarized as follows:

  • Polarity: The compound possesses both polar and non-polar functional groups. This dual nature typically affects its solubility in solvents.
  • Solvent Compatibility: 3-(2-phenylacetyl)-1H-indole-5-carbonitrile is expected to be more soluble in organic solvents such as dimethyl sulfoxide (DMSO) or ethanol compared to water, which is relatively polar.
  • Temperature Effects: Solubility can increase with temperature. Thus, experimenting at elevated temperatures might enhance its dissolution in certain solvents.
  • Potential Applications: Its solubility profile might lend itself well to pharmaceutical formulations, especially in drug delivery systems where solvent interactions are paramount.

While 3-(2-phenylacetyl)-1H-indole-5-carbonitrile may not have extensive documented solubility data, it is crucial to evaluate its behavior in potential solvent systems to optimize its use. Experimentation is key to harnessing its complete potential!

Interesting facts

Interesting Facts about 3-(2-phenylacetyl)-1H-indole-5-carbonitrile

This fascinating compound, 3-(2-phenylacetyl)-1H-indole-5-carbonitrile, belongs to the indole family, which is known for its rich variety of biological activities. Here are some key points to consider:

  • Biological Significance: Many indole derivatives exhibit significant pharmacological properties. This particular compound has drawn attention due to its potential as a pharmaceutical agent, with studies suggesting it may have anticancer properties.
  • Synthetic Versatility: The structure of this compound allows for various modifications, making it a versatile precursor for synthesizing other biologically active molecules.
  • Mechanism of Action: Researchers are exploring how this compound interacts with specific biological targets, which could lead to advancements in drug design and development. Preliminary data indicates it may inhibit certain enzymes that play a pivotal role in cell proliferation.
  • Research Implications: The structural features of 3-(2-phenylacetyl)-1H-indole-5-carbonitrile facilitate its use in medicinal chemistry. It presents a valuable scaffold for designing new compounds that might tackle drug-resistant strains of diseases.

In summary, 3-(2-phenylacetyl)-1H-indole-5-carbonitrile is more than just a chemical formula; it embodies a potential gateway to new medical therapies and a deeper understanding of indole derivatives in biochemical research. As one scientist noted, "The study of such compounds may illuminate pathways to innovative treatment options that were previously unimaginable."

Synonyms
5-Cyano-3-(phenylacetyl) indole
INDOLE-5-CARBONITRILE, 3-(PHENYLACETYL)-
3-(Phenylacetyl)indole-5-carbonitrile
17380-23-3
DTXSID40169665
DTXCID6092156