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Pravadoline

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Identification
Molecular formula
C16H20N2
CAS number
92386-86-4
IUPAC name
3-(2-pyrrolidin-1-ylethyl)-1H-indole
State
State

At room temperature, Pravadoline is typically a solid compound.

Melting point (Celsius)
166.00
Melting point (Kelvin)
439.15
Boiling point (Celsius)
442.50
Boiling point (Kelvin)
715.65
General information
Molecular weight
268.36g/mol
Molar mass
268.3710g/mol
Density
1.2200g/cm3
Appearence

Pravadoline appears as an off-white to pale yellow crystalline powder.

Comment on solubility

Solubility of 3-(2-pyrrolidin-1-ylethyl)-1H-indole

The solubility of 3-(2-pyrrolidin-1-ylethyl)-1H-indole is a key characteristic that can influence its potential applications in various fields. This compound, which may be used in pharmacology or organic chemistry, showcases specific solubility properties that are important to consider:

  • Solvent Interaction: 3-(2-pyrrolidin-1-ylethyl)-1H-indole generally exhibits solubility in polar aprotic solvents like DMSO or DMF, making these solvents suitable for dissolution when preparing solutions for experimental purposes.
  • pH Dependence: The solubility can be influenced by the pH of the solution. It is advisable to evaluate the solubility at various pH levels, particularly if the compound interacts with acidic or basic environments.
  • Temperature Effect: As with many organic compounds, an increase in temperature usually enhances solubility. Therefore, users should consider this factor when determining the appropriate conditions for solution preparation.
  • Hydrophobic Characteristics: Due to the indole moiety, this compound may possess hydrophobic characteristics which can limit solubility in highly polar solvents, thereby creating a need for careful solvent selection.

In summary, it is essential to test the solubility of 3-(2-pyrrolidin-1-ylethyl)-1H-indole under varied conditions to optimize its performance in relevant applications. Remember, "the solubility of a compound is not only influenced by its chemical structure but also by the environment in which it is placed."

Interesting facts

Exploring 3-(2-pyrrolidin-1-ylethyl)-1H-indole

3-(2-pyrrolidin-1-ylethyl)-1H-indole, often referred to in the realm of medicinal chemistry, presents a blend of intriguing structures and potential applications. This compound features an indole ring, a well-known structure in numerous bioactive molecules. Here are some fascinating points to consider:

  • Indole Core: The indole moiety is notable for being a part of many natural products and pharmaceuticals, facilitating its presence in various biological systems.
  • Pyrrolidine Influence: The incorporation of the pyrrolidinyl group plays a vital role in enhancing the binding affinity of the molecule towards biological targets. This modification can influence pharmacodynamics considerably.
  • Medicinal Applications: Compounds like 3-(2-pyrrolidin-1-ylethyl)-1H-indole are being explored for their potential as psychoactive substances or in the treatment of neurological disorders, drawing interest from both scientists and pharmacologists.
  • Synthetic Routes: The synthesis of this compound can involve various organic reactions, making it an interesting study for chemists who desire to expand their expertise in synthetic organic chemistry.
  • Emerging Research: Ongoing studies are investigating the compound's interactions at the molecular level, aiming to uncover its mechanisms of action in biological systems, which could lead to innovative therapeutic strategies.

As we continue to delve deeper into the realm of chemical compounds like 3-(2-pyrrolidin-1-ylethyl)-1H-indole, we unveil a tapestry of structural intricacies and biological potential that inspire a deeper understanding of medicinal chemistry and its applications.

Synonyms
Pyr-T
BRN 0166399
3-(2-(1-Pyrrolidinyl)ethyl)indole
VZ689W7HWX
1H-Indole, 3-(2-(1-pyrrolidinyl)ethyl)-
3-[2-(1-pyrrolidinyl)ethyl]-1H-indole
3-(2-(Pyrrolidin-1-yl)ethyl)-1H-indole
DTXSID00161226
5-22-10-00057 (Beilstein Handbook Reference)
3-[2-(Pyrrolidin-1-yl)ethyl]-1H-indole
3-(2-(1-PYRROLIDINYL)ETHYL)-1H-INDOLE
DTXCID4083717
1H-Indole, 3-(2-(1-pyrrolidinyl)ethyl)-(9CI)
3-(2-Pyrrolidinylethyl)indole
14008-96-9
INDOLE, 3-(2-(1-PYRROLIDINYL)ETHYL)-
UNII-VZ689W7HWX
N,N-tetramethylenetryptamine
SCHEMBL733629
SCHEMBL27095401
SCHEMBL27191699
SCHEMBL29543272
CVTZCBLFHNGYDQ-UHFFFAOYSA-N
PAA00896
DB-378498
Q7263202