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Psilocin

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Identification
Molecular formula
C12H16N2O
CAS number
520-53-6
IUPAC name
3-(2-pyrrolidin-2-ylethyl)-1H-indol-5-ol
State
State
At room temperature, psilocin is typically found in a solid state. It is usually handled in powder form for scientific and research purposes.
Melting point (Celsius)
173.00
Melting point (Kelvin)
446.15
Boiling point (Celsius)
376.70
Boiling point (Kelvin)
649.85
General information
Molecular weight
204.27g/mol
Molar mass
204.2690g/mol
Density
1.5574g/cm3
Appearence
Psilocin is a pale brown crystalline solid. It is a natural compound and one of the active substances in some psychedelic mushrooms. The compound is sensitive to oxidation, which can cause it to change color when exposed to air.
Comment on solubility

Solubility of 3-(2-pyrrolidin-2-ylethyl)-1H-indol-5-ol

The compound 3-(2-pyrrolidin-2-ylethyl)-1H-indol-5-ol exhibits interesting solubility characteristics that can influence its behavior in various applications. Solubility is a vital property that determines how a compound interacts in different environments. Here are some insights into the solubility of this specific compound:

  • Polar and Non-polar Interactions: The presence of both the indole moiety and the pyrrolidinyl group suggests a balance of polar and non-polar characteristics. This can affect its solubility in polar solvents like water as well as in non-polar solvents like hexane.
  • Hydrogen Bonding: The hydroxyl group (-OH) in the indole portion can form hydrogen bonds with solvent molecules, potentially enhancing its solubility in polar solvents.
  • Solvent Variability: Solubility may significantly vary depending on the solvent used. For example, while it may dissolve well in alcohols or dimethyl sulfoxide (DMSO), its solubility in water could be limited.

In summary, the solubility of 3-(2-pyrrolidin-2-ylethyl)-1H-indol-5-ol is influenced by its molecular structure, polarity, and the ability to engage in hydrogen bonding. Understanding these factors is crucial for anyone looking to utilize this compound in chemical or pharmaceutical applications.

Interesting facts

Interesting Facts About 3-(2-Pyrrolidin-2-ylethyl)-1H-Indol-5-ol

3-(2-Pyrrolidin-2-ylethyl)-1H-indol-5-ol is a fascinating compound that has garnered attention due to its unique structure and potential applications in various fields. Let’s explore some intriguing aspects of this compound:

  • Structure and Complexity: This compound features an indole moiety, which is a fundamental structure in many biologically active molecules. The incorporation of a pyrrolidine ring adds to its structural diversity, making it a molecule of interest for chemical studies.
  • Biological Significance: Compounds containing indole structures often exhibit a range of biological activities. This particular compound may have implications in the development of pharmaceuticals, especially in the context of neurological disorders.
  • Potential Applications: The unique combination of the pyrrolidine and indole structures suggests that this compound could be investigated as a potential drug candidate, particularly in the realm of antidepressant and anxiolytic medications.
  • Chemical Synthesis: The synthesis of compounds like this one often involves advanced organic chemistry techniques that can be intricate and challenging. Scientists often use strategies such as multi-step synthesis and catalytic reactions to achieve the desired product.
  • Research Opportunities: As research continues, this compound represents a promising avenue for studies in medicinal chemistry. Understanding its mechanism of action could unlock new treatments for various illnesses.

Overall, 3-(2-Pyrrolidin-2-ylethyl)-1H-indol-5-ol stands out not just for its chemical structure, but also for its potential impact on the future of pharmaceutical sciences. As scientist and student alike delve deeper into its properties, we may discover even more about this fascinating compound.

Synonyms
BRN 0401484
1919-95-5
5-Hydroxy-3-(2-pyrrolidinylethyl)indole
Indole, 5-hydroxy-3-(2-pyrrolidinylethyl)-
INDOL-5-OL, 3-(2-PYRROLIDINYLETHYL)-
5-22-12-00038 (Beilstein Handbook Reference)
DTXSID40940830
3-[2-(Pyrrolidin-2-yl)ethyl]-1H-indol-5-ol