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Etodolac

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Identification
Molecular formula
C17H21NO2
CAS number
41340-25-4
IUPAC name
3-[2,3-bis(4-methoxyphenyl)indol-1-yl]-N,N-diethyl-propan-1-amine
State
State

At room temperature, Etodolac is in solid state.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.15
Boiling point (Celsius)
552.60
Boiling point (Kelvin)
825.80
General information
Molecular weight
287.37g/mol
Molar mass
267.3640g/mol
Density
1.1054g/cm3
Appearence

Etodolac appears as a white or almost white crystalline powder.

Comment on solubility

Solubility of 3-[2,3-bis(4-methoxyphenyl)indol-1-yl]-N,N-diethyl-propan-1-amine

The solubility of 3-[2,3-bis(4-methoxyphenyl)indol-1-yl]-N,N-diethyl-propan-1-amine, a complex organic compound, can vary significantly based on several factors, including the solvent type, temperature, and the presence of other solutes. Key points to consider regarding its solubility include:

  • Polarity: Being an amine with multiple aromatic groups, it has non-polar characteristics that may limit solubility in polar solvents.
  • Solvent Interaction: It is generally more soluble in organic solvents such as dimethyl sulfoxide (DMSO), ethanol, or methanol compared to water, due to its hydrophobic aromatic rings.
  • Temperature Influence: Increased temperature can enhance solubility for many compounds, including this one, due to increased molecular motion.
  • pH Effects: The solubility may also be influenced by the pH of the solution, as protonation of the amine group can alter its aqueous solubility.

In summary, while 3-[2,3-bis(4-methoxyphenyl)indol-1-yl]-N,N-diethyl-propan-1-amine shows poor solubility in water, it exhibits better solubility in various organic solvents. Therefore, when working with this compound, it is important to choose the right solvent to achieve the desired solubility.

Interesting facts

Interesting Facts About 3-[2,3-bis(4-methoxyphenyl)indol-1-yl]-N,N-diethyl-propan-1-amine

This compound, which belongs to a class of indole derivatives, showcases the fascinating interplay between organic chemistry and medicinal applications. Here are some intriguing insights into this unique compound:

  • Structure and Functionality: The structural configuration of this indole derivative contributes to its potential biological activities, making it an interesting candidate for research in pharmacology.
  • Medicinal Potential: Compounds featuring the indole scaffold have been extensively studied for their therapeutic properties, including anti-cancer and anti-inflammatory effects. The presence of substituents like methoxyphenyl groups may enhance its biological activity.
  • Synthetic Pathways: The synthesis of such complex organic molecules often involves multi-step reactions, showcasing the creativity and ingenuity of synthetic chemists. Understanding these pathways is crucial for developing efficient methods to produce the compound.
  • Application in Drug Discovery: Due to the diverse functionalization potential of the indole core, this compound could be an exciting lead in drug discovery, prompting further exploration of its bioactivity.

As with many indole derivatives, ongoing research could uncover more about its role in various biological systems. Scientists often say, "In chemistry, every compound tells a story," and this compound is no exception. It represents a journey of exploration in organic synthesis and medicinal chemistry.

In summary, the intricate design and promising applications of 3-[2,3-bis(4-methoxyphenyl)indol-1-yl]-N,N-diethyl-propan-1-amine makes it a compelling subject for further investigation, highlighting the evolving landscape of chemical research.

Synonyms
BRN 1514045
INDOLE, 2,3-BIS(p-METHOXYPHENYL)-1-(3-(DIETHYLAMINO)PROPYL)-
DTXSID30206533
5782-01-4
1-(3-(Diethylamino)propyl)-2,3-bis(p-methoxyphenyl)indole
5-21-05-00445 (Beilstein Handbook Reference)
DTXCID60129024