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Tacrine

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Identification
Molecular formula
C13H14N2
CAS number
321-64-2
IUPAC name
3-(2,3,4,4a,9,9a-hexahydro-1H-acridin-10-yl)-N-methyl-propan-1-amine
State
State

At room temperature, Tacrine is a solid. It is typically found as a crystalline powder, indicating its detailed physical state.

Melting point (Celsius)
204.00
Melting point (Kelvin)
477.15
Boiling point (Celsius)
408.00
Boiling point (Kelvin)
681.15
General information
Molecular weight
198.27g/mol
Molar mass
198.2870g/mol
Density
1.3000g/cm3
Appearence

Tacrine, also known as tetrahydroaminoacridine (THA), is a solid compound that appears as white to pale yellow crystalline powder.

Comment on solubility

Solubility of 3-(2,3,4,4a,9,9a-hexahydro-1H-acridin-10-yl)-N-methyl-propan-1-amine

The solubility of 3-(2,3,4,4a,9,9a-hexahydro-1H-acridin-10-yl)-N-methyl-propan-1-amine can be influenced by various factors, including its molecular structure, functional groups, and environmental conditions. Here are some key points to consider:

  • Hydrophobic interactions: The presence of a large, hydrophobic acridine core could limit the compound's solubility in polar solvents such as water.
  • Polarity: The N-methyl group adds some level of polarity, potentially enhancing solubility in organic solvents like ethanol or methanol.
  • pH effects: Changes in pH can affect the protonation state of the amine group, which may enhance solubility in acidic or basic solutions.
  • Solvent selection: The compound might exhibit better solubility in organic solvents compared to aqueous environments, thus emphasizing the importance of choosing the right solvent for dissolution.

As such, understanding the solubility profile of this compound is crucial for its applications in various fields, including pharmaceutical formulations. It's essential to assess its solubility under different conditions for optimal usage.

Interesting facts

Interesting Facts about 3-(2,3,4,4a,9,9a-hexahydro-1H-acridin-10-yl)-N-methyl-propan-1-amine

This compound is quite fascinating as it belongs to a class of molecules known for their potential applications in medicinal chemistry, particularly in the field of pharmacology. The unique structure of this compound allows it to interact with biological systems in intriguing ways.

Key Highlights:

  • Structural Complexity: The presence of the acridine moiety adds a rich, polycyclic structure to the molecule, which is known to exhibit various biological activities.
  • Versatile Interactions: Its ability to span different interaction modes makes it a candidate for studying receptor binding, which is pivotal in drug design.
  • Pharmacological Potential: Compounds like this one are often investigated for their potential effects on neurological disorders, given the influence of acridine derivatives on neurotransmitter systems.
  • Research Opportunities: The ongoing studies into the effects of similar compounds on cellular pathways provide a wealth of knowledge that can lead to innovative therapeutic agents.

As the renowned chemist Linus Pauling once said, "The best way to have a good idea is to have lots of ideas." With compounds like 3-(2,3,4,4a,9,9a-hexahydro-1H-acridin-10-yl)-N-methyl-propan-1-amine, researchers continue to explore novel avenues in medicinal chemistry.

In summary, the unique characteristics of this compound not only contribute to its scientific intrigue but also hint at its potential as a therapeutic agent in the future. Its complex structure is just the beginning of its story in the captivating world of chemistry.