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Tacrine

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Identification
Molecular formula
C13H14N2
CAS number
321-64-2
IUPAC name
3-(2,3,4,4a,9,9a-hexahydro-1H-acridin-10-yl)-N,N-dimethyl-propan-1-amine
State
State

At room temperature, Tacrine is a solid.

Melting point (Celsius)
198.00
Melting point (Kelvin)
471.15
Boiling point (Celsius)
365.00
Boiling point (Kelvin)
638.15
General information
Molecular weight
198.28g/mol
Molar mass
198.2790g/mol
Density
1.1200g/cm3
Appearence

Tacrine appears as an off-white solid in its pure form.

Comment on solubility

Solubility of 3-(2,3,4,4a,9,9a-hexahydro-1H-acridin-10-yl)-N,N-dimethyl-propan-1-amine

The solubility of 3-(2,3,4,4a,9,9a-hexahydro-1H-acridin-10-yl)-N,N-dimethyl-propan-1-amine is an important characteristic to explore. While exact solubility values can often vary based on factors such as temperature and solvent choice, some general observations can be made:

  • Polarity: The presence of amine groups typically suggests some degree of polarity which can enhance solubility in polar solvents.
  • Hydrogen Bonding: The amine functional groups are capable of forming hydrogen bonds, potentially increasing solubility in aqueous solutions.
  • Hydrophobic Characteristics: The acridine ring system may introduce hydrophobic characteristics, which can limit solubility in water but enhance solubility in nonpolar organic solvents.

In general, compounds similar to this structure tend to exhibit a mixed solubility profile. It’s essential to systematically evaluate solubility in various solvents such as water, methanol, and dichloromethane to fully understand its behavior.

In the words of chemists: 'Understanding solubility is pivotal to unlocking the vast potential of any chemical compound.' Thus, investigating its solubility across a range of conditions can provide insights beneficial for practical applications.

Interesting facts

Exploring 3-(2,3,4,4a,9,9a-hexahydro-1H-acridin-10-yl)-N,N-dimethyl-propan-1-amine

This unique compound, known for its intricate structure and intriguing properties, belongs to a class of organic molecules that has garnered significant interest in the field of medicinal chemistry.

Key Features

  • Complex Holistic Structure: The molecule contains a hexahydroacridine core, which is notable for its potential to interact with various biological targets due to its three-dimensional arrangement.
  • Biological Relevance: Compounds like this one are often explored for their pharmacological potential, particularly in the development of new therapeutic agents against neurological disorders.
  • Dimethylamine Group: The presence of a dimethylamino group contributes to its basicity and can influence its interaction with receptors in the body, thereby impacting its bioactivity.

As noted by chemists, "The synthesis of complex organic compounds is often a dance between creativity and precision." This saying encapsulates the challenges faced in developing such multi-functional molecules.

Potential Applications

  • Pharmaceutical Development: Due to its structural features, this compound might be a candidate for research in drug development aimed at treating various neurological conditions.
  • Research Tools: Its distinct characteristics may also find utility in biochemical research, furthering the understanding of structure-activity relationships in drug design.

In conclusion, 3-(2,3,4,4a,9,9a-hexahydro-1H-acridin-10-yl)-N,N-dimethyl-propan-1-amine serves as an illustration of how complex organic molecules can provide profound insights into the development of new therapeutic strategies.