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Tacrine

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Identification
Molecular formula
C13H14N2
CAS number
321-64-2
IUPAC name
3-(2,3,4,4a,9,9a-hexahydro-1H-acridin-10-yl)propyl-methyl-ammonium;4-hydroxy-4-oxo-but-2-enoate
State
State

The compound is a solid at room temperature and is often handled and stored as such in laboratory and clinical settings.

Melting point (Celsius)
197.00
Melting point (Kelvin)
470.15
Boiling point (Celsius)
358.50
Boiling point (Kelvin)
631.65
General information
Molecular weight
198.26g/mol
Molar mass
198.2620g/mol
Density
1.2000g/cm3
Appearence

Tacrine is typically described as a white crystalline solid, which may sometimes appear as a pale solid due to impurities or variations in synthesis.

Comment on solubility

Solubility of 3-(2,3,4,4a,9,9a-hexahydro-1H-acridin-10-yl)propyl-methyl-ammonium;4-hydroxy-4-oxo-but-2-enoate

This compound exhibits a unique solubility profile influenced by its complex structure. In particular, the presence of the hexahydro-acridine moiety may affect its interaction with solvents. Here are some key points about its solubility:

  • Polarity: The overall polarity of the molecule significantly impacts its solubility in different solvents. A polar functional group often enhances solubility in polar solvents, while non-polar sections may favor non-polar solvents.
  • Water Solubility: Due to the presence of the ammonium group, this compound may display some degree of solubility in water, especially when ionized.
  • Solvent Compatibility: It likely shows varied solubility in organic solvents such as ethanol, methanol, or acetone, compared to aliphatic hydrocarbons.
  • pH Dependence: The solubility could change with pH due to the acid-base properties of the functional groups present.

In conclusion, the solubility of this compound is multifaceted and can be influenced by factors such as temperature, pH, and the choice of solvent. Further studies may provide a clearer understanding of its solubility dynamics across various environmental conditions.

Interesting facts

Interesting Facts about 3-(2,3,4,4a,9,9a-hexahydro-1H-acridin-10-yl)propyl-methyl-ammonium; 4-hydroxy-4-oxo-but-2-enoate

This compound is a fascinating blend of organic chemistry and medicinal potential, showcasing the intricate design in pharmaceutical chemistry. Below are some interesting aspects that highlight its significance:

  • Complex Structure: The compound features a unique hexahydro-acridine framework that contributes to its potential biological activity. The acridine family is known for its role in various therapeutic applications.
  • Ammonium Group: The inclusion of a quaternary ammonium moiety enhances solubility and bioavailability, making it a subject of interest in drug delivery systems.
  • Cyclic Components: The hexahydro structure is crucial in mimicking biological systems, providing insight into the development of potential neuroactive compounds.
  • Potential Applications: The dual nature of this compound hints at uses in both medicinal applications, particularly as a neuroprotective agent, and in organic synthesis, providing versatile pathways for compound modification.

Quote from a leading chemist: "The beauty of organic compounds is in their diversity and potential; each unique structure carries a story of its own.” This sentiment resonates particularly well with innovative compounds such as this one, which continue to inspire researchers.

Understanding compounds like these not only broadens our knowledge of chemistry but also opens doors to new therapeutic avenues that could transform healthcare and treatment methodologies.