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Varenicline

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Identification
Molecular formula
C13H13N3
CAS number
249296-44-4
IUPAC name
3-(2,3,4,5-tetrahydropyridin-6-yl)pyridine
State
State

At room temperature, varenicline is a solid. It is commonly available as tablets for oral administration.

Melting point (Celsius)
230.50
Melting point (Kelvin)
503.65
Boiling point (Celsius)
299.80
Boiling point (Kelvin)
572.95
General information
Molecular weight
211.27g/mol
Molar mass
211.2690g/mol
Density
1.2740g/cm3
Appearence

Varenicline is typically found as a crystalline solid. It is odourless and has a white to off-white color.

Comment on solubility

Solubility of 3-(2,3,4,5-tetrahydropyridin-6-yl)pyridine

The solubility of 3-(2,3,4,5-tetrahydropyridin-6-yl)pyridine is a multifaceted aspect that can significantly affect its applications in various chemical processes. Understanding its solubility characteristics is crucial for optimizing its use in reactions and formulations.

Factors Influencing Solubility

Several factors influence the solubility of this compound:

  • Polarity: The presence of both pyridine rings and the tetrahydropyridin moiety suggests a degree of polarity, which can affect interactions with solvents.
  • Hydrogen Bonding: The functional groups within the molecule may engage in hydrogen bonding, potentially increasing solubility in polar solvents.
  • Temperature: As with many organic compounds, the solubility may increase with rising temperatures, making it vital to consider temperature when conducting experiments.

Solvent Compatibility

In terms of solvent compatibility, 3-(2,3,4,5-tetrahydropyridin-6-yl)pyridine may exhibit:

  • High solubility in: Polar solvents such as water or methanol due to potential dipole-dipole interactions.
  • Limited solubility in: Nonpolar solvents like hexane, which may not effectively solvate the compound.

Overall, the solubility behavior of 3-(2,3,4,5-tetrahydropyridin-6-yl)pyridine is essential for its practical use and warrants careful consideration in both laboratory and industrial contexts.

Interesting facts

Interesting Facts about 3-(2,3,4,5-Tetrahydropyridin-6-yl)pyridine

3-(2,3,4,5-Tetrahydropyridin-6-yl)pyridine is a fascinating compound that has garnered attention in various fields of research due to its unique structure and potential applications. Below are some engaging facts about this compound:

  • Structural Insight: The compound features a pyridine ring, which is a six-membered aromatic ring containing one nitrogen atom. Additionally, it is fused with a tetrahydropyridine moiety, which provides flexibility in its chemical behavior.
  • Biological Relevance: Compounds related to pyridine structures, especially those containing nitrogen-rich heterocycles, often exhibit significant biological activities. Researchers are exploring its potential as a pharmacological agent, contributing to advancements in medicinal chemistry.
  • Versatile Applications: The unique chemical properties of this compound make it suitable for applications in organic synthesis, agrochemicals, and the development of functional materials.
  • Novel Derivatives: Scientists are continually investigating derivatives of pyridine and tetrahydropyridine to optimize their properties for specific uses, which could lead to the discovery of innovative solutions in drug development.
  • Research Trends: The rising interest in nitrogen-containing heterocycles reflects broader trends in chemistry, particularly in the search for new catalysts and materials that are efficient and environmentally friendly.

In summary, 3-(2,3,4,5-Tetrahydropyridin-6-yl)pyridine represents a blend of structural complexity and functional versatility, making it a compound of interest not just within academia but also in industrial applications. Its ongoing study is paving the way for new discoveries that may revolutionize various sectors.

Synonyms
Anabaseine
3471-05-4
3,4,5,6-Tetrahydro-2,3'-bipyridine
3-(2,3,4,5-tetrahydropyridin-6-yl)pyridine
2,3'-BIPYRIDINE, 3,4,5,6-TETRAHYDRO-
BRN 0125981
DYE103K23I
UNII-DYE103K23I
DTXSID50188266
5-23-06-00507 (Beilstein Handbook Reference)
DTXCID80110757
3-(3,4,5,6-tetrahydropyridin-2-yl)pyridine
CHEBI:80787
SCHEMBL261062
CHEMBL1230982
US8609708, 74 Anabaseine
BDBM109773
AKOS000277414
HY-115766
CS-0255607
NS00010542
C16906
EN300-269722
Q19903288
AN4