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Diclofenac

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Identification
Molecular formula
C14H11Cl2NO2
CAS number
15307-86-5
IUPAC name
3-(2,4-dichlorophenyl)prop-2-enoic acid
State
State

At room temperature, Diclofenac is in a solid state.

Melting point (Celsius)
165.00
Melting point (Kelvin)
438.15
Boiling point (Celsius)
318.00
Boiling point (Kelvin)
591.15
General information
Molecular weight
296.15g/mol
Molar mass
296.1480g/mol
Density
1.5900g/cm3
Appearence

Solid white crystalline powder that is slightly hygroscopic. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of 3-(2,4-dichlorophenyl)prop-2-enoic acid

The solubility of 3-(2,4-dichlorophenyl)prop-2-enoic acid, also known as dichlorophenyl acrylic acid, can be quite interesting and can influence its application in various fields. This compound exhibits unique solubility characteristics due to its chemical structure and the presence of the 2,4-dichlorophenyl group.

Factors Affecting Solubility:

  • Polarity: The presence of a carboxylic acid functional group (–COOH) contributes to its polarity, which enhances solubility in polar solvents like water.
  • Hydrophobic Interactions: The aromatic chlorinated ring increases hydrophobic interactions, potentially decreasing solubility in nonpolar solvents.
  • Temperature: Like many organic acids, solubility may be affected by temperature; typically, higher temperatures can lead to increased solubility.

It’s essential to note that while 3-(2,4-dichlorophenyl)prop-2-enoic acid is moderately soluble in water, its solubility in organic solvents can vary significantly. Experimentation is key to understanding the precise solubility characteristics in different environments.

In conclusion, the solubility of 3-(2,4-dichlorophenyl)prop-2-enoic acid is influenced by multiple factors, making it a compound of interest for specific applications ranging from pharmaceuticals to materials science.

Interesting facts

Interesting Facts About 3-(2,4-Dichlorophenyl)prop-2-enoic Acid

3-(2,4-Dichlorophenyl)prop-2-enoic acid, commonly referred to in the scientific community for its intriguing structure and reactivity, presents several notable aspects:

  • Structure: The presence of a 2,4-dichlorophenyl group contributes to the compound's molecular properties, particularly its reactivity and potential biological activity.
  • Applications: This compound has been studied for its role in the synthesis of herbicides and can serve as an important intermediate in organic synthesis.
  • Biological Significance: Some derivatives of this compound have shown promise as pharmaceuticals, exhibiting anti-inflammatory and anti-cancer properties.
  • Research Scope: Ongoing research focuses on this compound's mechanism of action, interactions with enzymes, and potential pathways for therapeutic applications.

As a scientist or chemistry student, you might be particularly fascinated by the way the chlorine atoms influence the compound’s reactivity. The halogen substituents usually enhance the electron-withdrawing capabilities of aromatic systems, which can significantly affect the compound's acidity and nucleophilicity.

Furthermore, the study of such compounds bridges the gap between organic chemistry and medicinal chemistry, illustrating how intricate molecular configurations can lead to diverse chemical behaviors and biological effects. As the famous chemist Linus Pauling once said, "The best way to have a good idea is to have lots of ideas." The exploration of compounds like this one is a testament to that philosophy, opening the door to innovative developments in both chemical research and practical applications.

Synonyms
3-(2,4-dichlorophenyl)prop-2-enoic acid
(e)-2,4-dichlorocinnamic acid
DTXSID00870866
MEBWABJHRAYGFW-UHFFFAOYSA-N
SY048515
SY113651
DB-041539