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Dihydrochalcone

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Identification
Molecular formula
C15H12O3
CAS number
2075-77-6
IUPAC name
3-(2,4-dihydroxyphenyl)-1-phenyl-prop-2-en-1-one
State
State

At room temperature, dihydrochalcone is typically found as a solid. The solid nature is due to its aromatic rings and conjugated carbonyl system which provide a stable crystalline structure. It can be ground into a fine powder for different applications.

Melting point (Celsius)
79.15
Melting point (Kelvin)
352.30
Boiling point (Celsius)
421.15
Boiling point (Kelvin)
694.30
General information
Molecular weight
258.24g/mol
Molar mass
258.2440g/mol
Density
1.2054g/cm3
Appearence

Dihydrochalcone compounds typically appear as yellow crystalline solids or powders. They exhibit a crystalline structure with a characteristic shimmer and bright hue, indicative of their aromatic and conjugated system.

Comment on solubility

Solubility of 3-(2,4-dihydroxyphenyl)-1-phenyl-prop-2-en-1-one

The solubility of 3-(2,4-dihydroxyphenyl)-1-phenyl-prop-2-en-1-one is an intriguing aspect due to its structural features. Understanding its solubility can give insights into its behavior in various solvents and applications. Here are some key points to consider:

  • Polarity: The presence of multiple hydroxyl groups (-OH) contributes to the polarity of this compound, usually enhancing its solubility in polar solvents.
  • Solvent Interaction: 3-(2,4-dihydroxyphenyl)-1-phenyl-prop-2-en-1-one may demonstrate varying solubility in solvents like water, ethanol, and acetone, which are typically good solvents for polar compounds.
  • Hydrogen Bonding: The ability of the hydroxyl groups to engage in hydrogen bonding can significantly increase solubility in polar environments.
  • Temperature Influence: As with many organic compounds, solubility may increase with temperature, allowing for more effective dissolution in higher temperatures.
  • Concentration Factors: The concentration of the compound plays a crucial role; at higher concentrations, solubility limits may be reached quickly.

In summary, while explicit solubility values for 3-(2,4-dihydroxyphenyl)-1-phenyl-prop-2-en-1-one may vary, understanding its characteristics can provide a framework for predicting its behavior in different solvent environments:

  1. Assess the polarity and functional groups present.
  2. Experiment with various solvents to determine solubility.
  3. Consider temperature effects during dissolution.

The exploration of solubility for this compound opens avenues for applications in pharmaceuticals, organic synthesis, and materials science.

Interesting facts

Interesting Facts about 3-(2,4-Dihydroxyphenyl)-1-phenyl-prop-2-en-1-one

The compound 3-(2,4-dihydroxyphenyl)-1-phenyl-prop-2-en-1-one is a fascinating member of the flavonoid family, often discussed in the realm of organic chemistry and natural products. This compound stands out for several reasons:

  • Biological Activity: It possesses impressive biological properties, including antioxidant, anti-inflammatory, and anticancer activities. This makes it a subject of interest for researchers exploring natural compounds for therapeutic applications.
  • Natural Sources: This compound can be derived from various plants, showcasing the richness of natural products in medicinal chemistry. Many flavonoids are known for their roles in plant defense mechanisms, and this compound is no exception.
  • Chemical Structure: The presence of both hydroxyl groups and a phenyl moiety contributes to its reactivity and interaction with biological targets. These structural features enhance its ability to scavenge free radicals and stabilize cellular structures.
  • Synthesis Potential: Chemists are particularly intrigued by the synthetic routes to this compound, often employing methods that involve the coupling of phenolic compounds. Its synthesis opens doors to exploring derivatives that may enhance its beneficial health effects.
  • Research Trends: Ongoing research aims to understand its mechanism of action at the molecular level and the potential it holds for drug development, particularly in cancer treatment and prevention.

As quoted by many researchers: "The exploration of nature often leads to revolutionary discoveries in chemistry." Understanding compounds like 3-(2,4-dihydroxyphenyl)-1-phenyl-prop-2-en-1-one exemplifies this sentiment, highlighting the importance of the connection between natural products and their synthetic counterparts in developing tomorrow's therapies.


This compound is an excellent example of how the study of chemical compounds extends far beyond the lab, influencing healthcare, environmental studies, and agricultural practices.

Synonyms
3-(2,4-Dihydroxyphenyl)-1-phenyl-2-propen-1-one
92496-59-8
SCHEMBL3995353
DTXSID001241645