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Galipea officinalis structure (synthetic analog)

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Identification
Molecular formula
C18H17NO4
CAS number
548-19-6
IUPAC name
3-[(2,4,6-trimethoxyphenyl)methylene]indolin-2-one
State
State

State: At room temperature, the compound exists as a solid. Its crystalline nature and the structural stability provided by the phenylmethylene and indolinone groups contribute to its solid state under standard conditions.

Melting point (Celsius)
120.00
Melting point (Kelvin)
393.15
Boiling point (Celsius)
450.00
Boiling point (Kelvin)
723.15
General information
Molecular weight
321.34g/mol
Molar mass
321.3380g/mol
Density
1.3456g/cm3
Appearence

Appearance: The compound is typically a crystalline solid, often appearing as pale yellow to tan colored crystals or powder. The presence of methoxy groups might contribute to subtle color variations depending on the level of purity and specific crystallization method used.

Comment on solubility

Solubility of 3-[(2,4,6-trimethoxyphenyl)methylene]indolin-2-one (C18H17NO4)

The solubility of 3-[(2,4,6-trimethoxyphenyl)methylene]indolin-2-one exhibits notable characteristics that are influenced by its structural components. This compound, bearing multiple methoxy groups, suggests a tendency towards solubility in organic solvents. Here are key points regarding its solubility:

  • Polar Solvents: The presence of oxygen atoms in the methoxy functional groups may impart some polar characteristics, enhancing its solubility in polar solvents to a limited extent.
  • Non-Polar Solvents: Given the hydrophobic nature of the indolic structure, it is expected to demonstrate better solubility in non-polar organic solvents such as dichloromethane and ethyl acetate.
  • Water Solubility: Its anticipated low water solubility is aligned with many organic compounds that include large aromatic systems, which often hinder interactions with polar solvent molecules.
  • Concentration Effects: The degree of solubility may vary with concentration, temperature, and the presence of other solvents or solutes.

In conclusion, the solubility profile of C18H17NO4 is primarily governed by its organic nature and structural functionalities, making it more soluble in organic solvents while maintaining low solubility in water.

Interesting facts

Interesting Facts about 3-[(2,4,6-trimethoxyphenyl)methylene]indolin-2-one

The compound 3-[(2,4,6-trimethoxyphenyl)methylene]indolin-2-one is a fascinating member of the indole alkaloid family, known for its remarkable structural and functional properties. Here are some engaging insights into this intriguing compound:

  • Versatile Chemistry: This compound showcases diverse reactivity patterns, making it a valuable precursor in organic synthesis.
  • Potential Biological Activity: Many indole derivatives are known for their biological significance, including anti-cancer, anti-inflammatory, and antimicrobial properties. Research is ongoing to explore the pharmacological potential of this specific compound.
  • Scaffold for Drug Development: The unique indolin-2-one structure serves as a crucial scaffold in drug design, potentially leading to novel therapeutics targeting various diseases.
  • Aromatic Features: The presence of the 2,4,6-trimethoxyphenyl group adds to its aromatic character, which can enhance its interactions with biological systems, thus making it a subject of interest in medicinal chemistry.
  • Research Insights: According to recent studies, compounds like this one can significantly influence various biochemical pathways, leading to novel strategies in cancer treatment.

This compound illustrates the intersection of chemistry and biology, highlighting the importance of structural diversity in the development of new medication. As research progresses, 3-[(2,4,6-trimethoxyphenyl)methylene]indolin-2-one may pave the way for new discoveries in therapeutic applications.

Synonyms
3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one
IC-261
SU5607
Maybridge3_000754
CHEMBL576349
GTPL5985
3-[(2,4,6-trimethoxyphenyl)methylidene]-2,3-dihydro-1H-indol-2-one
DTXSID201017155
BCP16652
BDBM50008516
AKOS026750487
IC-261(SU-5607)
I1077
Q27078020
IC-261;IC261;SU5607; SU-5607; SU 5607; SU 5607