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Dothiepin hydrochloride

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Identification
Molecular formula
C19H23Cl2NS
CAS number
897-55-2
IUPAC name
3-(2,9-dichloro-6,11-dihydrobenzo[c][1]benzothiepin-11-yl)propyl-dimethyl-ammonium;chloride
State
State

At room temperature, Dothiepin hydrochloride is typically a solid. It is commonly found in its crystalline powder form, which is stable under normal conditions of storage and use.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
390.00
Boiling point (Kelvin)
663.15
General information
Molecular weight
327.31g/mol
Molar mass
327.3100g/mol
Density
1.2400g/cm3
Appearence

Dothiepin hydrochloride typically presents as a white to pale yellow crystalline powder. It is known for being homogeneous and free-flowing, with a fine particulate appearance. The compound is often odorless or nearly so.

Comment on solubility

Solubility of 3-(2,9-dichloro-6,11-dihydrobenzo[c][1]benzothiepin-11-yl)propyl-dimethyl-ammonium;chloride

The solubility of 3-(2,9-dichloro-6,11-dihydrobenzo[c][1]benzothiepin-11-yl)propyl-dimethyl-ammonium;chloride presents noteworthy characteristics primarily due to its ionic nature.

Key Points on Solubility

  • Highly Soluble in Water: Being a quaternary ammonium compound, it exhibits a good degree of solubility in water due to the positively charged ammonium ion.
  • Influenced by Ionic Strength: The addition of salts can potentially enhance its solubility by decreasing the activity of the ions.
  • Solvent Dependency: Solubility can vary significantly in different solvents; while it dissolves well in polar solvents, its solubility in non-polar solvents is expected to be low.
  • Temperature Effects: Increased temperature usually enhances solubility, particularly for ionic compounds.

As quoted, “Like dissolves like,” highlighting that ionic compounds often find good solubility within polar solvents. Thus, for practical applications and formulations, understanding the solubility behavior of this compound is crucial for successful implementation in various chemical processes and formulations.

Interesting facts

Interesting Facts about 3-(2,9-Dichloro-6,11-dihydrobenzo[c][1]benzothiepin-11-yl)propyl-dimethyl-ammonium; Chloride

This compound, a fascinating member of the class of quaternary ammonium salts, showcases an intricate structure that is both unique and noteworthy in the field of chemical research. Below are some interesting aspects that highlight its significance and potential applications:

  • Pharmacological Potential: The complex aromatic structure suggests that this compound may have interesting pharmacological activities. Research into similar compounds has often revealed properties that include antipsychotic, antihistaminic, and antimuscarinic effects.
  • Chlorine Atoms: The inclusion of chlorine substituents is particularly intriguing; they can greatly influence both the reactivity and the biological activity of organic compounds. Chlorination is known to enhance solubility and metabolic stability, making it a topic of interest in drug design.
  • Quaternary Ammonium Compounds: As a quaternary ammonium salt, this substance possesses unique properties such as antimicrobial activity, making it potentially useful in disinfectants and antiseptics, a focus area in medical and industrial applications.
  • Complex Synthesis Pathways: The synthesis of such complex molecular architectures often requires innovative synthetic methodologies. Understanding these pathways can provide insights into synthetic organic chemistry and medicinal chemistry, along with enhancing skills in designing and optimizing chemical reactions.
  • Historical Context: Compounds with similar backbones have historical significance in the development of anti-psychotic medications. Studying this compound might contribute to the ongoing research in mental health treatments.

As we delve deeper into the chemistry of such compounds, we are reminded of the intricate relationship between molecular structure and function. The exploration of 3-(2,9-Dichloro-6,11-dihydrobenzo[c][1]benzothiepin-11-yl)propyl-dimethyl-ammonium; chloride could open doors to new therapeutic avenues and a better understanding of chemical interactions. As researchers, there is always something new to learn from compounds with such rich chemical backgrounds.