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Nucleotide structure (example of a modified nucleotide)

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Identification
Molecular formula
C9H13N3O7
CAS number
.Not Assigned
IUPAC name
3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-4,6-bis(hydroxyamino)-4,5-dihydropyrimidin-2-one
State
State

At room temperature, this compound is typically found in a solid state, characterized by its crystalline appearance and stability. It remains solid under standard conditions.

Melting point (Celsius)
159.00
Melting point (Kelvin)
432.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
275.22g/mol
Molar mass
274.2410g/mol
Density
1.5048g/cm3
Appearence

The compound is typically in a crystalline solid form, often appearing as white to off-white crystals or powder. The exact appearance may vary depending on the specific form and hydration state of the compound when isolated.

Comment on solubility

Solubility of 3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-4,6-bis(hydroxyamino)-4,5-dihydropyrimidin-2-one

The solubility of this particular compound is influenced by its intricate structure, which includes multiple functional groups. Compounds with hydrophilic properties often exhibit good solubility in polar solvents such as water. In this case, the presence of hydroxy groups enhances the compound's ability to interact with water molecules, thus potentially increasing its solubility.

Key factors that may affect the solubility include:

  • Functional Groups: The multiple hydroxy groups can form hydrogen bonds with the solvent.
  • Steric Hindrance: The three-dimensional shape of the molecule can impact its interaction with solvent molecules.
  • pH Level: Depending on the pH, certain groups may become protonated or deprotonated, affecting solubility.

In summary, while the complex structure suggests that the compound is likely to be soluble in polar solvents, precise solubility data can only be obtained through experimental measurement. The combination of both structural considerations and environmental conditions plays a critical role.

Interesting facts

Interesting Facts about 3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-4,6-bis(hydroxyamino)-4,5-dihydropyrimidin-2-one

This compound, often referred to in scientific literature, showcases the fascinating interplay between carbohydrates and heterocyclic compounds. Here are some engaging insights:

  • Structural Complexity: The compound's structure is notable for its dual moieties—a tetrahydrofuran sugar-like unit and a bis(hydroxyamino)-dihydropyrimidinone backbone. This combination highlights the versatility and intricacy of organic synthesis and biotechnology.
  • Biological Relevance: Compounds with structural similarities may exhibit biological activity, particularly as potential pharmaceuticals. For example, the pyrimidinone framework is often found in nucleoside analogs.
  • Synthesis Considerations: The synthesis of such compounds involves careful synthetic strategies, often employing stereo-specific reactions to ensure the correct configuration of the stereogenic centers, particularly the sugar component.
  • Role in Research: This compound may be explored within the context of drug development, especially in the search for anti-viral or anti-cancer agents due to its structural features that could mimic natural substrates for key enzymes in these processes.

As a student or researcher in the field of chemistry, understanding the properties and potential applications of this compound underscores the exciting **possibilities** in medicinal chemistry and materials science. The presence of multiple functional groups opens the door for various reaction pathways, thereby expanding its application in **synthetic strategies**.

In conclusion, the study of such compounds not only advances our knowledge of organic chemistry but also paves the way for the development of innovative solutions to contemporary health challenges.