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Iodixanol

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Identification
Molecular formula
C35H44I6N6O15
CAS number
92339-11-2
IUPAC name
3-[[3-[3-carboxy-2,4,6-triiodo-5-(methylcarbamoyl)anilino]-3-oxo-propanoyl]amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid;6-(methylamino)hexane-1,2,3,4,5-pentol
State
State

Iodixanol is typically encountered in a solution form for usage as an injectable radiopaque medium, appearing as a clear, colorless liquid. In its solid state, it is a crystalline powder.

Melting point (Celsius)
251.00
Melting point (Kelvin)
524.15
Boiling point (Celsius)
255.00
Boiling point (Kelvin)
528.15
General information
Molecular weight
1550.20g/mol
Molar mass
1 550.1980g/mol
Density
2.0110g/cm3
Appearence

Iodixanol appears as a white, hygroscopic, crystalline powder. It is commonly dissolved in water to form a colorless, clear solution used for medical imaging purposes.

Comment on solubility

Solubility of 3-[[3-[3-carboxy-2,4,6-triiodo-5-(methylcarbamoyl)anilino]-3-oxo-propanoyl]amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid;6-(methylamino)hexane-1,2,3,4,5-pentol

The solubility of the compound 3-[[3-[3-carboxy-2,4,6-triiodo-5-(methylcarbamoyl)anilino]-3-oxo-propanoyl]amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid;6-(methylamino)hexane-1,2,3,4,5-pentol can be described in several key aspects:

  • Polarity: This compound exhibits significant polarity due to the presence of carboxyl and amino functional groups, which enhance its interaction with polar solvents like water.
  • Hydrophilic and Hydrophobic Balance: The triiodinated aromatic structure indicates a degree of hydrophobicity. The overall solubility will largely depend on the balance of hydrophilic (water-attracting) and hydrophobic (water-repelling) regions within the structure.
  • Saturation Limits: In practical applications, the solubility is also influenced by concentration. There may be saturation points beyond which the compound may not dissolve effectively.
  • pH Sensitivity: Being a carboxylic acid, its solubility is likely to be pH-dependent, where increased acidity could enhance solubility through ionization, while basic conditions could lead to precipitation.

In general, solubility is a multifactorial aspect influenced by structural components and environmental conditions. Therefore, to ascertain the precise solubility of this compound, empirical testing under varying conditions would prove invaluable.

Interesting facts

Interesting Facts about 3-[[3-[3-carboxy-2,4,6-triiodo-5-(methylcarbamoyl)anilino]-3-oxo-propanoyl]amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid; 6-(methylamino)hexane-1,2,3,4,5-pentol

This compound, with its complex architecture, showcases the rich combination of various functional groups and halides which provide a foundation for incredible biological activity and potential therapeutic applications.

Key Features:

  • Triiodo Substituents: The presence of multiple iodine atoms makes this compound notable for its high X-ray attenuation properties, aiding in imaging techniques such as computed tomography (CT) scans.
  • Carboxylic Acids: The carboxy group enhances its ability to form complexes with metal ions and contributes to the compound's potential as a drug candidate.
  • Methylcarbamoyl Groups: These functional groups impart additional hydrogen bonding capability, which can enhance solubility in biological systems or improve interactions with receptor sites.

Additionally, the integration of a hexane pentol structure is particularly intriguing. Pentols are known to exert osmotic effects and act as stabilizers in various biological applications. This aspect could be significant for enhancing the efficacy of drug delivery systems.

An exciting quote about the potential of such compounds states, "The design of multifunctional compounds may lead to new horizons in drug discovery and therapy." Given the diverse functional groups present, breakthroughs in medicinal chemistry utilizing this compound could revolutionize treatment methods for a variety of conditions.

Your exploration of this compound offers not only scientific intrigue but also a glimpse into its potential roles in advancing medical technology and therapeutic practices.

Synonyms
AC1L1MGK
DTXSID50274936
3-[[3-[3-carboxy-2,4,6-triiodo-5-(methylcarbamoyl)anilino]-3-oxopropanoyl]amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid;6-(methylamino)hexane-1,2,3,4,5-pentol