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Iopamidol

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Identification
Molecular formula
C17H22I3N3O8
CAS number
60166-93-0
IUPAC name
3-[[3-[3-carboxy-2,4,6-triiodo-5-(methylcarbamoyl)anilino]-3-oxo-propanoyl]amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid
State
State

At room temperature, Iopamidol is a solid.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.15
Boiling point (Celsius)
710.00
Boiling point (Kelvin)
983.15
General information
Molecular weight
777.09g/mol
Molar mass
777.0900g/mol
Density
2.1000g/cm3
Appearence

Iopamidol appears as a solid that is typically a white to off-white crystalline powder. It is known for its high iodine content, which contributes to its opacity and effectiveness for use as a contrast agent in medical imaging.

Comment on solubility

Solubility of 3-[[3-[3-carboxy-2,4,6-triiodo-5-(methylcarbamoyl)anilino]-3-oxo-propanoyl]amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid

This compound, a complex organic molecule, exhibits noteworthy solubility characteristics. The presence of multiple functional groups, such as carboxylic acid and amide functionalities, deeply influences its solubility profile.

When considering solubility, several key factors come into play:

  • Polarity: The presence of polar functional groups enhances its ability to interact with polar solvents, such as water.
  • Ionic interactions: The carboxylic acid group can ionize, which may increase solubility in aqueous environments.
  • Hydrogen bonding: The (methylcarbamoyl) groups are capable of forming hydrogen bonds, further promoting solubility in various solvents.

However, due to the substantial number of iodine atoms, predicting solubility solely based on functional groups can be challenging. Typically, compounds with high iodine content tend to exhibit lower solubility in water.

In conclusion, while this compound may show solubility in some polar solvents due to its functional groups, its overall solubility can be affected by the presence of the iodine substituents, which may lead to less favorable interactions with water. For practical applications, it is advised to conduct empirical solubility tests to ascertain its behavior in specific solvents.

Interesting facts

Interesting Facts About 3-[[3-[3-carboxy-2,4,6-triiodo-5-(methylcarbamoyl)anilino]-3-oxo-propanoyl]amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoic Acid

This compound is a complex organic molecule that exhibits notable biological activity and structural characteristics. Here are some intriguing aspects of this fascinating compound:

  • Iodinated Aromatic Compound: The presence of multiple iodine atoms in the structure gives this compound unique properties, potentially enhancing its effectiveness in medical applications, especially as a contrast agent in imaging techniques.
  • Carboxylic Acid Functionality: As a carboxylic acid, it can participate in various chemical reactions, making it versatile for synthetic applications in organic chemistry.
  • Methylcarbamoyl Groups: The methylcarbamoyl substituents suggest the compound might exhibit interesting interactions in biological systems, particularly in drug design where such modifications can enhance metabolic stability.
  • Structure-Activity Relationship (SAR): The intricately designed structure of this compound allows chemists to explore how changes to its framework might affect its biological activity, providing invaluable insights into therapeutic development.

This compound's synthesis may involve multiple steps, demonstrating the intricate processes chemists engage in to produce complex molecules. The study of such a compound expands our understanding of chemical interactions and the potential for drug development in therapeutic avenues, including oncology and imaging science.

Overall, 3-[[3-[3-carboxy-2,4,6-triiodo-5-(methylcarbamoyl)anilino]-3-oxo-propanoyl]amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid is a prime example of how modifications at the molecular level can lead to significant practical applications in real-world scenarios.